GWAS1121745_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1121745_H (triglyceride measurement QTL GWAS1121745 (human)) Homo sapiens

Symbol: GWAS1121745_H
Name: triglyceride measurement QTL GWAS1121745 (human)
RGD ID: 597025671
Trait: triglyceride measurement
Measurement Type: blood triglyceride level   (CMO:0000118)    
LOD Score: Not Available
P Value: 3.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382046,975,601 - 46,975,602RGD_MAPPER_PIPELINEGRCh38
GRCh372045,604,240 - 45,604,241RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1121745_HHumanblood triglyceride level  IAGPrs6063050405850206 GWAS_CATALOGPMID:30698716

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1121745_HHumantriglyceride measurement  IAGPrs6063050405850206 GWAS_CATALOGPMID:30698716

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1350703EYA2EYA transcriptional coactivator and phosphatase 2204689484347188844Human


Peak: (rs6063050)
Human AssemblyChrPosition (strand)Source
GRCh382046,975,601 - 46,975,602RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407070915GWAS719891_Htriglyceride measurement, alcohol drinking QTL GWAS719891 (human)0.0000004triglyceride measurement, alcohol drinkingblood triglyceride level (CMO:0000118)204697560146975602Human
597025671GWAS1121745_Htriglyceride measurement QTL GWAS1121745 (human)0.000003triglyceride measurementblood triglyceride level (CMO:0000118)204697560146975602Human
597588396GWAS1645256_Hglucose measurement QTL GWAS1645256 (human)7e-12glucose measurementblood glucose level (CMO:0000046)204697560146975602Human
1300007BP29_HBlood pressure QTL 29 (human)Blood pressurehypertension susceptibility203653600562536005Human
596962176GWAS1081695_Hmetabolic syndrome QTL GWAS1081695 (human)5e-13metabolic syndrome204697560146975602Human
407073917GWAS722893_Htriglyceride measurement, alcohol drinking QTL GWAS722893 (human)3e-08triglyceride measurement, alcohol drinkingblood triglyceride level (CMO:0000118)204697560146975602Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1121745_H GCST008087 Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 0.000003 5.523 rs6063050 0.011 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS1645256_H GCST90479625 Glucose (fasting status unknown, maximum, inv-norm transformed) 117,850 African American or Afro-Caribbean individuals, 57,272 Hispanic or Latin American individuals, 6,318 East Asian ancestry individuals, 419,671 European ancestry individuals T 0.7561 7E-12 11.155 rs6063050 0.02172 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1714179_H GCST008074 Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 5E-7 6.302 rs6063050 N/A triglyceride measurement (EFO:0004530)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS1714493_H GCST008074 Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 5E-8 7.302 rs6063050 N/A triglyceride measurement (EFO:0004530)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS719891_H GCST008083 Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 4E-7 6.398 rs6063050 N/A triglyceride measurement (EFO:0004530)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS722893_H GCST008083 Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 3E-8 7.523 rs6063050 N/A triglyceride measurement (EFO:0004530)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS1081695_H GCST90444487 Metabolic syndrome 1,384,348 European ancestry individuals ? NR 5E-13 12.302 rs6063050 0.00975433 metabolic syndrome (EFO:0000195)
 PMID:39349817
Database
Acc Id
Source(s)
GWAS Catalog GCST008087 GWAS Catalog

Note Type Note Reference