GWAS1117364_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1117364_H (Crohn's disease QTL GWAS1117364 (human)) Homo sapiens

Symbol: GWAS1117364_H
Name: Crohn's disease QTL GWAS1117364 (human)
RGD ID: 597021290
Trait: intestine integrity trait   (VT:0010554)    
LOD Score: Not Available
P Value: 6.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38690,263,440 - 90,263,441RGD_MAPPER_PIPELINEGRCh38
GRCh37690,973,159 - 90,973,160RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1117364_HHumanCrohn's disease  IAGPrs1847472405850206 GWAS_CATALOGPMID:28067908

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1117364_HHumanCrohn's disease  IAGPrs1847472405850206 GWAS_CATALOGPMID:28067908

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1117364_HHumanintestine integrity trait  IAGPrs1847472405850206 GWAS_CATALOGPMID:28067908

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1117364_HHumanCrohn's disease  IAGPrs1847472405850206 GWAS_CATALOGPMID:28067908

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1319503BACH2BTB domain and CNC homolog 268992652890296843Human


Peak: (rs1847472)
Human AssemblyChrPosition (strand)Source
GRCh38690,263,440 - 90,263,441RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597020950GWAS1117024_Hinflammatory bowel disease QTL GWAS1117024 (human)2e-09inflammatory bowel disease69026344090263441Human
406894566GWAS543542_Hankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis QTL GWAS543542 (human)5e-10intestine integrity trait (VT:0010554)69026344090263441Human
597093025GWAS1189099_Hinflammatory bowel disease QTL GWAS1189099 (human)7e-10inflammatory bowel disease69026344090263441Human
597092526GWAS1188600_HCrohn's disease QTL GWAS1188600 (human)1e-10intestine integrity trait (VT:0010554)69026344090263441Human
1298426BFD3_HBody fluid distribution QTL 3 (human)2.790.01Body fluid distributionimpedance ratio684873647110873647Human
407162127GWAS811103_Hinflammatory bowel disease QTL GWAS811103 (human)2e-10inflammatory bowel disease69026344090263441Human
407126538GWAS775514_HCrohn's disease QTL GWAS775514 (human)5e-09intestine integrity trait (VT:0010554)69026344090263441Human
597021290GWAS1117364_HCrohn's disease QTL GWAS1117364 (human)6e-09intestine integrity trait (VT:0010554)69026344090263441Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1117364_H GCST004132 Crohn's disease 12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls ? NR 6E-9 8.222 rs1847472 N/A Crohn's disease (EFO:0000384)
 PMID:28067908
GWAS543542_H GCST005537 Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls ? NR 5E-10 9.302 rs1847472 N/A ankylosing spondylitis (EFO:0003898)
psoriasis (EFO:0000676)
ulcerative colitis (EFO:0000729)
Crohn's disease (EFO:0000384)
More... 		PMID:26974007
GWAS1117024_H GCST004131 Inflammatory bowel disease 25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls ? NR 2E-9 8.699 rs1847472 N/A inflammatory bowel disease (EFO:0003767)
 PMID:28067908
GWAS1188600_H GCST003044 Crohn's disease 5,956 European ancestry cases, 14,927 European ancestry controls C 0.66 1E-10 10 rs1847472 1.0891367 Crohn's disease (EFO:0000384)
 PMID:26192919
GWAS1189099_H GCST003043 Inflammatory bowel disease 12,882 European ancestry cases, 21,770 European ancestry controls C 0.66 7E-10 9.155 rs1847472 1.0695955 inflammatory bowel disease (EFO:0003767)
 PMID:26192919
GWAS1732256_H GCST90313902 CD79B/TNFRSF13B protein level ratio 43,509 European ancestry individuals ? NR 4E-23 22.398 rs1847472 0.0709174 CD79B/TNFRSF13B protein level ratio in blood (OBA:2053373)
 PMID:38412862
GWAS775514_H GCST000879 Crohn's disease 6,333 European ancestry cases, 15,056 European ancestry controls G 0.658 5E-9 8.302 rs1847472 1.07 Crohn's disease (EFO:0000384)
 PMID:21102463
GWAS811103_H GCST001725 Inflammatory bowel disease 12,924 European ancestry cases, 21,442 European ancestry controls C 0.655 2E-10 9.699 rs1847472 1.06 inflammatory bowel disease (EFO:0003767)
 PMID:23128233
Database
Acc Id
Source(s)
GWAS Catalog GCST004132 GWAS Catalog

Note Type Note Reference