GWAS1115623_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1115623_H (smoking status measurement, systolic blood pressure QTL GWAS1115623 (human)) Homo sapiens

Symbol: GWAS1115623_H
Name: smoking status measurement, systolic blood pressure QTL GWAS1115623 (human)
RGD ID: 597019549
Trait: smoking status measurement, systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 4.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,797,469 - 11,797,470RGD_MAPPER_PIPELINEGRCh38
GRCh37111,857,526 - 11,857,527RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115623_HHumansystolic blood pressure  IAGPrs6541006405850206 GWAS_CATALOGPMID:29455858

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115623_HHumansmoking status measurement  IAGPrs6541006405850206 GWAS_CATALOGPMID:29455858
GWAS1115623_HHumansystolic blood pressure  IAGPrs6541006405850206 GWAS_CATALOGPMID:29455858

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
733483MTHFRmethylenetetrahydrofolate reductase11178572311805964Human


Peak: (rs6541006)
Human AssemblyChrPosition (strand)Source
GRCh38111,797,469 - 11,797,470RGD_MAPPER_PIPELINE


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597019953GWAS1116027_Hsmoking status measurement, systolic blood pressure QTL GWAS1116027 (human)4e-14smoking status measurement, systolic blood pressuresystolic blood pressure (CMO:0000004)11179746911797470Human
597019549GWAS1115623_Hsmoking status measurement, systolic blood pressure QTL GWAS1115623 (human)4e-15smoking status measurement, systolic blood pressuresystolic blood pressure (CMO:0000004)11179746911797470Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597019078GWAS1115152_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115152 (human)5e-10smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11179746911797470Human
597019169GWAS1115243_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115243 (human)3e-14smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11179746911797470Human
597019616GWAS1115690_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115690 (human)6e-10smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11179746911797470Human
597019753GWAS1115827_Hsmoking status measurement, systolic blood pressure QTL GWAS1115827 (human)2e-17smoking status measurement, systolic blood pressuresystolic blood pressure (CMO:0000004)11179746911797470Human

1 to 10 of 13 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1115623_H GCST006195 Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 4E-15 14.398 rs6541006 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
GWAS1115152_H GCST006193 Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 5E-10 9.302 rs6541006 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115243_H GCST006193 Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 3E-14 13.523 rs6541006 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115474_H GCST006195 Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 3E-19 18.523 rs6541006 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
GWAS1115506_H GCST006190 Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 5E-14 13.302 rs6541006 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115690_H GCST006190 Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 6E-10 9.222 rs6541006 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115827_H GCST006192 Systolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 2E-17 16.699 rs6541006 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
GWAS1116027_H GCST006192 Systolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 4E-14 13.398 rs6541006 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
Database
Acc Id
Source(s)
GWAS Catalog GCST006195 GWAS Catalog

Note Type Note Reference