GWAS1099147_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1099147_H (hypothyroidism QTL GWAS1099147 (human)) Homo sapiens

Symbol: GWAS1099147_H
Name: hypothyroidism QTL GWAS1099147 (human)
RGD ID: 596979628
Trait: hypothyroidism
LOD Score: Not Available
P Value: 8.0E-41
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38690,170,674 - 90,170,675RGD_MAPPER_PIPELINEGRCh38
GRCh37690,880,393 - 90,880,394RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1319503BACH2BTB domain and CNC homolog 268992652890296843Human


Peak: (rs10944479)
Human AssemblyChrPosition (strand)Source
GRCh38690,170,674 - 90,170,675RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597279880GWAS1375954_Hhypothyroidism QTL GWAS1375954 (human)8e-41hypothyroidism69017067490170675Human
597190345GWAS1286419_Hsystemic lupus erythematosus QTL GWAS1286419 (human)5e-13systemic lupus erythematosus69017067490170675Human
597049972GWAS1146046_Hcutaneous squamous cell carcinoma QTL GWAS1146046 (human)4e-09cutaneous squamous cell carcinoma69017067490170675Human
1298426BFD3_HBody fluid distribution QTL 3 (human)2.790.01Body fluid distributionimpedance ratio684873647110873647Human
596979628GWAS1099147_Hhypothyroidism QTL GWAS1099147 (human)8e-41hypothyroidism69017067490170675Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1707427_H GCST002378 Thyroid peroxidase antibody positivity 1,769 European ancestry cases, 16,528 European ancestry controls A 0.16 4E-8 7.398 rs10944479 1.25 obsolete_thyroid peroxidase antibody measurement (EFO:0005666)
 PMID:24586183
GWAS1146046_H GCST010148 Cutaneous squamous cell carcinoma 19,149 European ancestry cases, 680,049 European ancestry controls A 0.189 4E-9 8.398 rs10944479 0.09 cutaneous squamous cell carcinoma (EFO:1001927)
 PMID:32041948
GWAS1286419_H GCST90270940 Systemic lupus erythematosus (MTAG) at least 5,877 East Asian ancestry cases, at least 188,588 East Asian ancestry controls, at least 14,355 European ancestry cases, at least 505,956 European ancestry controls, at least 1,393 admixed American ancestry cases, at least 2,327 admixed American ancestry controls (MTAG boosted by autoimmune diseases samples) G NR 5E-13 12.302 rs10944479 0.089 PMID:36750564
GWAS1375954_H GCST90319320 Hypothyroidism 58,783 European ancestry cases, 633,203 European ancestry controls A NR 8E-41 40.097 rs10944479 1.15 hypothyroidism (EFO:0004705)
 PMID:39067062
Database
Acc Id
Source(s)
GWAS Catalog GCST90319320 GWAS Catalog

Note Type Note Reference