GWAS1079855_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1079855_H (lymphocyte count QTL GWAS1079855 (human)) Homo sapiens

Symbol: GWAS1079855_H
Name: lymphocyte count QTL GWAS1079855 (human)
RGD ID: 596960336
Trait: lymphocyte count
LOD Score: Not Available
P Value: 2.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,738,432 - 10,738,433RGD_MAPPER_PIPELINEGRCh38
GRCh37110,798,489 - 10,798,490RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1606535CASZ1castor zinc finger 111063660410796646Human
38674269LOC110121258VISTA enhancer hs209411073482110739184Human


Peak: (rs34071855)
Human AssemblyChrPosition (strand)Source
GRCh38110,738,432 - 10,738,433RGD_MAPPER_PIPELINE


1 to 10 of 23 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
596974645GWAS1094164_Hmean arterial pressure, major depressive disorder QTL GWAS1094164 (human)5e-12mean arterial pressure, major depressive disorder11073843210738433Human
597036596GWAS1132670_Hdiastolic blood pressure, alcohol drinking QTL GWAS1132670 (human)2e-26diastolic blood pressure, alcohol drinkingdiastolic blood pressure (CMO:0000005)11073843210738433Human
407070727GWAS719703_Hurinary albumin to creatinine ratio QTL GWAS719703 (human)7e-10urine albumin amount (VT:0002871)urine albumin level to urine creatinine level ratio (CMO:0000384)11073843210738433Human
596960336GWAS1079855_Hlymphocyte count QTL GWAS1079855 (human)2e-10hypertension11073843210738433Human
597609722GWAS1666582_Hhypertension, family history QTL GWAS1666582 (human)2e-13hypertension, family history11073843210738433Human
597607003GWAS1663863_Htotal cholesterol measurement QTL GWAS1663863 (human)1e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)11073843210738433Human
597210865GWAS1306939_Hsystolic blood pressure QTL GWAS1306939 (human)4e-08systolic blood pressuresystolic blood pressure (CMO:0000004)11073843210738433Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597037594GWAS1133668_Hmean arterial pressure, alcohol drinking QTL GWAS1133668 (human)4e-20mean arterial pressure, alcohol drinkingmean arterial blood pressure (CMO:0000009)11073843210738433Human

1 to 10 of 23 rows


1 to 17 of 17 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1132670_H GCST006166 Diastolic blood pressure x alcohol consumption interaction (2df test) 63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers C 0.64 2E-26 25.699 rs34071855 N/A diastolic blood pressure (EFO:0006336)
alcohol drinking (EFO:0004329)
 PMID:29912962
GWAS1132781_H GCST006166 Diastolic blood pressure x alcohol consumption interaction (2df test) 63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers C 0.65 5E-29 28.302 rs34071855 N/A diastolic blood pressure (EFO:0006336)
alcohol drinking (EFO:0004329)
 PMID:29912962
GWAS1133668_H GCST006167 Mean arterial pressure x alcohol consumption interaction (2df test) 91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers C 0.65 4E-20 19.398 rs34071855 N/A mean arterial pressure (EFO:0006340)
alcohol drinking (EFO:0004329)
 PMID:29912962
GWAS1135724_H GCST007269 Pulse pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals G 0.6558 2E-10 9.699 rs34071855 0.1644 pulse pressure measurement (EFO:0005763)
 PMID:30578418
GWAS1663863_H GCST90476424 total cholesterol (mean, inv-norm transformed) 397,615 European ancestry individuals C 0.6593 1E-11 11 rs34071855 0.0184 total cholesterol measurement (EFO:0004574)
 PMID:39024449
GWAS1666582_H GCST90479695 Biological Mother: High blood pressure 22,718 African American or Afro-Caribbean cases, 32,787 African American or Afro-Caribbean controls, 8,387 Hispanic or Latin American cases, 20,927 Hispanic or Latin American controls, 1,148 East Asian ancestry cases, 2,399 East Asian ancestry controls, 81,790 European ancestry cases, 233,878 European ancestry controls C 0.6662 2E-13 12.699 rs34071855 0.043 hypertension (EFO:0000537)
family history (EFO:0000493)
 PMID:39024449
GWAS719703_H GCST008790 Urinary albumin-to-creatinine ratio 547,361 European ancestry individuals, 6,795 African American individuals, 6,324 East Asian ancestry individuals, 2,335 South Asian ancestry individuals, 1,442 Hispanic individuals C NR 7E-10 9.155 rs34071855 0.0131 urinary albumin to creatinine ratio (EFO:0007778)
 PMID:31511532
GWAS721057_H GCST008791 Microalbuminuria 51,861 European, African American, East Asian, South Asian or Hispanic ancestry cases, 297,093 European, African American, East Asian, South Asian or Hispanic ancestry controls G NR 6E-9 8.222 rs34071855 1.0432074 Moderate albuminuria (HP:0012594)
 PMID:31511532
GWAS1302155_H GCST007926 Medication use (antihypertensives) 6,431 European ancestry cases, 145,949 European ancestry controls G 0.339889 7E-9 8.155 rs34071855 0.110219374 Antihypertensive use measurement (EFO:0009927)
 PMID:31015401
GWAS1306939_H GCST011892 Systolic blood pressure (long-term average) 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals C 0.325 4E-8 7.398 rs34071855 0.7013 systolic blood pressure (EFO:0006335)
 PMID:33603002
GWAS952649_H GCST90002320 Lymphocyte count 643,370 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals G 0.402174 3E-10 9.523 rs34071855 N/A lymphocyte count (EFO:0004587)
 PMID:32888493
GWAS1371032_H GCST90093177 Mean arterial pressure x depressive symptoms interaction (2df test) 43,335 European ancestry individuals ? NR 5E-12 11.302 rs34071855 N/A mean arterial pressure (EFO:0006340)
 PMID:34734193
None Available GCST90446531 Hypertension 193,908 European ancestry cases, 265,230 European ancestry controls ? NR 2E-10 9.699 rs34071855 N/A hypertension (EFO:0000537)
 PMID:37947095
GWAS1389933_H GCST90018961 LDL cholesterol 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals G NR 5E-9 8.302 rs34071855 0.0134 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34594039
None Available GCST90018962 Lymphocyte count 349,856 European ancestry individuals, 95,717 East Asian ancestry individuals G NR 2E-10 9.699 rs34071855 0.0146 lymphocyte count (EFO:0004587)
 PMID:34594039
None Available GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals G NR 2E-10 9.699 rs34071855 0.0136 total cholesterol measurement (EFO:0004574)
 PMID:34594039
GWAS1413749_H GCST90435414 Diastolic blood pressure 404,337 European ancestry individuals ? NR 3E-26 25.523 rs34071855 0.0232435 diastolic blood pressure (EFO:0006336)
 PMID:39134668
1 to 17 of 17 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90018962 GWAS Catalog
  GCST90018974 GWAS Catalog
  GCST90446531 GWAS Catalog

Note Type Note Reference