GWAS1072233_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1072233_H (BMI-adjusted waist-hip ratio QTL GWAS1072233 (human)) Homo sapiens

Symbol: GWAS1072233_H
Name: BMI-adjusted waist-hip ratio QTL GWAS1072233 (human)
RGD ID: 596952714
Trait: BMI-adjusted waist-hip ratio
LOD Score: Not Available
P Value: 5.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38577,131,486 - 77,131,487RGD_MAPPER_PIPELINEGRCh38
GRCh37576,427,311 - 76,427,312RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
6770267ZBED3-AS1ZBED3 antisense RNA 157708671577149301Human
1348334PDE8Bphosphodiesterase 8B57708671577428256Human


Peak: (rs6878122)
Human AssemblyChrPosition (strand)Source
GRCh38577,131,486 - 77,131,487RGD_MAPPER_PIPELINE


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406981698GWAS630674_Htype 2 diabetes mellitus QTL GWAS630674 (human)5e-29type 2 diabetes mellitus57713148677131487Human
406952517GWAS601493_Htype 2 diabetes mellitus QTL GWAS601493 (human)5e-11type 2 diabetes mellitus57713148677131487Human
406952516GWAS601492_Htype 2 diabetes mellitus QTL GWAS601492 (human)3e-10type 2 diabetes mellitus57713148677131487Human
596962897GWAS1082416_Hhemoglobin A1 measurement QTL GWAS1082416 (human)7e-27hemoglobin A1 measurement57713148677131487Human
406976390GWAS625366_Htype 2 diabetes mellitus QTL GWAS625366 (human)1e-12type 2 diabetes mellitus57713148677131487Human
597024477GWAS1120551_Htype 2 diabetes mellitus QTL GWAS1120551 (human)3e-10type 2 diabetes mellitus57713148677131487Human
597208499GWAS1304573_Htype 2 diabetes mellitus QTL GWAS1304573 (human)1e-12type 2 diabetes mellitus57713148677131487Human
597144476GWAS1240550_HDrugs used in diabetes use measurement QTL GWAS1240550 (human)2e-09type 2 diabetes mellitus57713148677131487Human
406948845GWAS597821_HBMI-adjusted waist-hip ratio QTL GWAS597821 (human)5e-12BMI-adjusted waist-hip ratio57713148677131487Human
597281096GWAS1377170_Hhemoglobin A1 measurement QTL GWAS1377170 (human)7e-27hemoglobin A1 measurement57713148677131487Human

1 to 10 of 17 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1120551_H GCST005047 Type 2 diabetes 6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls G NR 3E-10 9.523 rs6878122 1.12 PMID:22885922
GWAS1120695_H GCST005047 Type 2 diabetes 6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls G 0.2799582088267 5E-11 10.302 rs6878122 1.1 PMID:22885922
GWAS1125067_H GCST008994 Waist-to-hip ratio adjusted for BMI 379,501 European ancestry female individuals A 0.6978 5E-12 11.302 rs6878122 0.013 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30239722
GWAS1183222_H GCST010555 Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls G 0.3114 5E-29 28.302 rs6878122 0.0554 PMID:32541925
GWAS1240550_H GCST90250911 Medication use for T2D (number of purchases) 567,671 European ancestry individuals ? NR 2E-9 8.699 rs6878122 0.006416 Drugs used in diabetes use measurement (EFO:0009924)
 PMID:36653479
None Available GCST90018926 Type 2 diabetes 38,841 European ancestry cases, 451,248 European ancestry controls, 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls A NR 2E-9 8.699 rs6878122 0.0547 PMID:34594039
GWAS1304573_H GCST006867 Type 2 diabetes 61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls G 0.318208634557753 1E-12 12 rs6878122 0.0564 PMID:30054458
GWAS1377170_H GCST90018958 Hemoglobin A1c levels 344,182 European ancestry individuals, 71,221 East Asian ancestry individuals A NR 7E-27 26.155 rs6878122 0.0262 hemoglobin A1 measurement (EFO:0007629)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST008994 GWAS Catalog

Note Type Note Reference