GWAS1066929_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1066929_H (brain volume measurement QTL GWAS1066929 (human)) Homo sapiens

Symbol: GWAS1066929_H
Name: brain volume measurement QTL GWAS1066929 (human)
RGD ID: 407417953
Trait: brain volume measurement
Measurement Type: brain morphological measurement   (CMO:0000136)    
LOD Score: Not Available
P Value: 1.0E-33
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381539,347,697 - 39,347,698RGD_MAPPER_PIPELINEGRCh38
GRCh371539,639,898 - 39,639,899RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1066929_HHumanbrain morphological measurement  IAGPrs4924345405850206Based on the EFO term IDGWAS_CATALOGPMID:33875891

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1066929_HHumanbrain volume measurement  IAGPrs4924345405850206 GWAS_CATALOGPMID:33875891
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38627269LOC105370777uncharacterized LOC105370777153886480639421060Human

Position Markers

Peak: (rs4924345)
Human AssemblyChrPosition (strand)Source
GRCh381539,347,697 - 39,347,698RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407381760GWAS1030736_Hcortical surface area measurement QTL GWAS1030736 (human)3e-38cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934769739347698Human
407381761GWAS1030737_Hcortical surface area measurement QTL GWAS1030737 (human)1e-56cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934769739347698Human
407416325GWAS1065301_Htotal cortical area measurement QTL GWAS1065301 (human)6e-20total cortical area measurement153934769739347698Human
406920846GWAS569822_Hneuroimaging measurement QTL GWAS569822 (human)0.000001neuroimaging measurement153934769739347698Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407415064GWAS1064040_Hbrain volume measurement QTL GWAS1064040 (human)9e-26brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407417950GWAS1066926_Hbrain volume measurement QTL GWAS1066926 (human)2e-26brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407418256GWAS1067232_Htotal cortical area measurement QTL GWAS1067232 (human)1e-20total cortical area measurement153934769739347698Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407415400GWAS1064376_Htotal cortical area measurement QTL GWAS1064376 (human)2e-22total cortical area measurement153934769739347698Human
407417641GWAS1066617_Hbrain volume measurement QTL GWAS1066617 (human)5e-72brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407415402GWAS1064378_Htotal cortical area measurement QTL GWAS1064378 (human)4e-18total cortical area measurement153934769739347698Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407418861GWAS1067837_Htotal cortical area measurement QTL GWAS1067837 (human)3e-18total cortical area measurement153934769739347698Human
407417965GWAS1066941_Hbrain volume measurement QTL GWAS1066941 (human)3e-15brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407417966GWAS1066942_Hbrain volume measurement QTL GWAS1066942 (human)4e-116brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407417647GWAS1066623_Hbrain volume measurement QTL GWAS1066623 (human)5e-18brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407415712GWAS1064688_Htotal cortical area measurement QTL GWAS1064688 (human)2e-20total cortical area measurement153934769739347698Human
407417953GWAS1066929_Hbrain volume measurement QTL GWAS1066929 (human)1e-33brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407415393GWAS1064369_Hbrain volume measurement QTL GWAS1064369 (human)9e-87brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407415394GWAS1064370_Hbrain volume measurement QTL GWAS1064370 (human)1e-15brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
407418873GWAS1067849_Htotal cortical area measurement QTL GWAS1067849 (human)3e-20total cortical area measurement153934769739347698Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
407381759GWAS1030735_Hcortical surface area measurement QTL GWAS1030735 (human)1e-14cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934769739347698Human
407066811GWAS715787_Hbrain volume measurement QTL GWAS715787 (human)4e-13brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
407371583GWAS1020559_Hneuroimaging measurement QTL GWAS1020559 (human)3e-50neuroimaging measurement153934769739347698Human
407371582GWAS1020558_Hneuroimaging measurement QTL GWAS1020558 (human)3e-53neuroimaging measurement153934769739347698Human
407090872GWAS739848_Hbrain volume measurement QTL GWAS739848 (human)2e-14brain volume measurementbrain morphological measurement (CMO:0000136)153934769739347698Human
406910204GWAS559180_Hneuroimaging measurement QTL GWAS559180 (human)2e-08neuroimaging measurement153934769739347698Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS559180_H GCST90385536 T1 FreeSurfer BA lh BA3b exvivo volume 7,058 Chinese Han ancestry individuals C NR 2E-8 7.699 rs4924345 0.365267 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS569822_H GCST90385677 T1 FreeSurfer DK lh postcentral volume 7,058 Chinese Han ancestry individuals C NR 0.000001 6 rs4924345 0.323746 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS715787_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 4E-13 12.398 rs4924345 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS739848_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 2E-14 13.699 rs4924345 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS1020558_H GCST006777 Brain imaging measurements 8,428 British ancestry individuals C 0.081185 3E-53 52.523 rs4924345 0.35321 neuroimaging measurement (EFO:0004346)
 PMID:30305740
GWAS1020559_H GCST006777 Brain imaging measurements 8,428 British ancestry individuals C 0.081185 3E-50 49.523 rs4924345 0.34292 neuroimaging measurement (EFO:0004346)
 PMID:30305740
GWAS1030735_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.9181 1E-14 14 rs4924345 12.818136 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS1030736_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.918 3E-38 37.523 rs4924345 67.905556 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS1030737_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.9181 1E-56 56 rs4924345 69.45024 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS1064040_H GCST90002818 aparc-Desikan rh volume parsopercularis 21,282 British ancestry individuals C 0.081 9E-26 25.046 rs4924345 0.188 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064369_H GCST90002789 aparc-Desikan lh volume postcentral 21,282 British ancestry individuals C 0.081 9E-87 86.046 rs4924345 0.351 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064370_H GCST90002798 aparc-Desikan lh volume supramarginal 21,282 British ancestry individuals C 0.081 1E-15 15 rs4924345 0.143 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064376_H GCST90003191 aparc-pial rh area parsopercularis 21,282 British ancestry individuals C 0.081 2E-22 21.699 rs4924345 0.174 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064378_H GCST90003193 aparc-pial rh area parstriangularis 21,282 British ancestry individuals C 0.081 4E-18 17.398 rs4924345 0.155 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064688_H GCST90003124 aparc-Desikan rh area parsopercularis 21,282 British ancestry individuals C 0.081 2E-20 19.699 rs4924345 0.166 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1065301_H GCST90003426 aparc-a2009s rh area S-intrapariet+P-trans 21,282 British ancestry individuals C 0.081 6E-20 19.222 rs4924345 0.164 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1066617_H GCST90002882 aparc-DKTatlas lh volume postcentral 21,282 British ancestry individuals C 0.081 5E-72 71.302 rs4924345 0.32 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066623_H GCST90002980 aparc-a2009s lh volume S-intrapariet+P-trans 21,282 British ancestry individuals C 0.081 5E-18 17.302 rs4924345 0.155 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066926_H GCST90002909 aparc-DKTatlas rh volume parsopercularis 21,282 British ancestry individuals C 0.081 2E-26 25.699 rs4924345 0.19 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066929_H GCST90002928 aparc-a2009s lh volume G+S-subcentral 21,282 British ancestry individuals C 0.081 1E-33 33 rs4924345 0.216 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066941_H GCST90002829 aparc-Desikan rh volume superiorparietal 21,282 British ancestry individuals C 0.081 3E-15 14.523 rs4924345 0.141 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066942_H GCST90002838 BA-exvivo lh volume BA3b 21,281 British ancestry individuals C 0.081 4E-116 115.398 rs4924345 0.407 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1067232_H GCST90003202 aparc-pial rh area superiorparietal 21,282 British ancestry individuals C 0.081 1E-20 20 rs4924345 0.167 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067837_H GCST90003352 aparc-a2009s lh area S-intrapariet+P-trans 21,282 British ancestry individuals C 0.081 3E-18 17.523 rs4924345 0.156 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067849_H GCST90003281 aparc-DKTatlas rh area parsopercularis 21,282 British ancestry individuals C 0.081 3E-20 19.523 rs4924345 0.164 total cortical area measurement (EFO:0008381)
 PMID:33875891
Database Acc Id Source(s)
GWAS Catalog GCST90002928 GWAS Catalog

RGD Curation Notes
Note Type Note Reference