GWAS1064691_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1064691_H (total cortical area measurement QTL GWAS1064691 (human)) Homo sapiens

Symbol: GWAS1064691_H
Name: total cortical area measurement QTL GWAS1064691 (human)
RGD ID: 407415715
Trait: total cortical area measurement
LOD Score: Not Available
P Value: 4E-85
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381539,342,021 - 39,342,022RGD_MAPPER_PIPELINEGRCh38
GRCh371539,634,222 - 39,634,223RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1064691_HHumantotal cortical area measurement  IAGPrs1080066405850206 GWAS_CATALOGPMID:33875891
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38627269LOC105370777uncharacterized LOC105370777153886480639421060Human

Position Markers

Peak: (rs1080066)
Human AssemblyChrPosition (strand)Source
GRCh381539,342,021 - 39,342,022RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406908865GWAS557841_Hneuroimaging measurement QTL GWAS557841 (human)8e-09neuroimaging measurement153934202139342022Human
407415371GWAS1064347_Hbrain volume measurement QTL GWAS1064347 (human)8e-62brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407415372GWAS1064348_Hbrain volume measurement QTL GWAS1064348 (human)3e-119brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
406909130GWAS558106_Hneuroimaging measurement QTL GWAS558106 (human)5e-10neuroimaging measurement153934202139342022Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407417951GWAS1066927_Hbrain volume measurement QTL GWAS1066927 (human)1e-70brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
406924251GWAS573227_Hneuroimaging measurement QTL GWAS573227 (human)0.000002neuroimaging measurement153934202139342022Human
407416018GWAS1064994_Htotal cortical area measurement QTL GWAS1064994 (human)4e-104total cortical area measurement153934202139342022Human
407416019GWAS1064995_Htotal cortical area measurement QTL GWAS1064995 (human)6e-145total cortical area measurement153934202139342022Human
407415380GWAS1064356_Hbrain volume measurement QTL GWAS1064356 (human)2e-90brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407419477GWAS1068453_Hbrain connectivity measurement QTL GWAS1068453 (human)8e-13brain connectivity measurement153934202139342022Human
407416023GWAS1064999_Htotal cortical area measurement QTL GWAS1064999 (human)9e-29total cortical area measurement153934202139342022Human
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407417960GWAS1066936_Hbrain volume measurement QTL GWAS1066936 (human)3e-21brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407417963GWAS1066939_Hbrain volume measurement QTL GWAS1066939 (human)1e-84brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407417964GWAS1066940_Hbrain volume measurement QTL GWAS1066940 (human)2e-74brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407418862GWAS1067838_Htotal cortical area measurement QTL GWAS1067838 (human)2e-14total cortical area measurement153934202139342022Human
407417967GWAS1066943_Hbrain volume measurement QTL GWAS1066943 (human)2e-39brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407417952GWAS1066928_Hbrain volume measurement QTL GWAS1066928 (human)1e-77brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407417956GWAS1066932_Hbrain volume measurement QTL GWAS1066932 (human)2e-68brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407417957GWAS1066933_Hbrain volume measurement QTL GWAS1066933 (human)8e-165brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
406929391GWAS578367_Hneuroimaging measurement QTL GWAS578367 (human)5e-08neuroimaging measurement153934202139342022Human
407417958GWAS1066934_Hbrain volume measurement QTL GWAS1066934 (human)1e-12brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407417959GWAS1066935_Hbrain volume measurement QTL GWAS1066935 (human)4e-53brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407418872GWAS1067848_Hbrain volume measurement QTL GWAS1067848 (human)4e-57brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
406989680GWAS638656_Hneuroimaging measurement QTL GWAS638656 (human)0.0000002neuroimaging measurement153934202139342022Human
407381755GWAS1030731_Hcortical surface area measurement QTL GWAS1030731 (human)3e-184cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934202139342022Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
407381756GWAS1030732_Hcortical surface area measurement QTL GWAS1030732 (human)3e-12cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934202139342022Human
407417968GWAS1066944_Hbrain volume measurement QTL GWAS1066944 (human)1e-62brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407418864GWAS1067840_Htotal cortical area measurement QTL GWAS1067840 (human)1e-61total cortical area measurement153934202139342022Human
406910460GWAS559436_Hneuroimaging measurement QTL GWAS559436 (human)2e-10neuroimaging measurement153934202139342022Human
407418868GWAS1067844_Htotal cortical area measurement QTL GWAS1067844 (human)2e-18total cortical area measurement153934202139342022Human
406910336GWAS559312_Hneuroimaging measurement QTL GWAS559312 (human)2e-11neuroimaging measurement153934202139342022Human
406938626GWAS587602_Hneuroimaging measurement QTL GWAS587602 (human)1e-08neuroimaging measurement153934202139342022Human
406910340GWAS559316_Hneuroimaging measurement QTL GWAS559316 (human)3e-09neuroimaging measurement153934202139342022Human
406920839GWAS569815_Hneuroimaging measurement QTL GWAS569815 (human)4e-08neuroimaging measurement153934202139342022Human
407418254GWAS1067230_Htotal cortical area measurement QTL GWAS1067230 (human)8e-53total cortical area measurement153934202139342022Human
407418255GWAS1067231_Htotal cortical area measurement QTL GWAS1067231 (human)7e-89total cortical area measurement153934202139342022Human
407407745GWAS1056721_Hbrain measurement, neuroimaging measurement QTL GWAS1056721 (human)1e-305brain measurement, neuroimaging measurementbrain measurement (CMO:0000911)153934202139342022Human
407416324GWAS1065300_Htotal cortical area measurement QTL GWAS1065300 (human)1e-131total cortical area measurement153934202139342022Human
407405063GWAS1054039_Hcortical surface area measurement, neuroimaging measurement QTL GWAS1054039 (human)1e-242cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934202139342022Human
406977936GWAS626912_Hneuroimaging measurement QTL GWAS626912 (human)3e-13neuroimaging measurement153934202139342022Human
407415702GWAS1064678_Htotal cortical area measurement QTL GWAS1064678 (human)1e-55total cortical area measurement153934202139342022Human
406921376GWAS570352_Hneuroimaging measurement QTL GWAS570352 (human)0.0000004neuroimaging measurement153934202139342022Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407417644GWAS1066620_Hbrain volume measurement QTL GWAS1066620 (human)2e-91total cortical area measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
406919463GWAS568439_Hneuroimaging measurement QTL GWAS568439 (human)0.0000001neuroimaging measurement153934202139342022Human
407417646GWAS1066622_Hbrain volume measurement QTL GWAS1066622 (human)5e-93brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human
407088548GWAS737524_Hcortical surface area measurement QTL GWAS737524 (human)2e-80cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934202139342022Human
407089451GWAS738427_Hcortical surface area measurement QTL GWAS738427 (human)1e-200cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934202139342022Human
407415715GWAS1064691_Htotal cortical area measurement QTL GWAS1064691 (human)4e-85total cortical area measurement153934202139342022Human
407406502GWAS1055478_Hcortical thickness, neuroimaging measurement QTL GWAS1055478 (human)7e-120cortical thickness, neuroimaging measurement153934202139342022Human
406919991GWAS568967_Hneuroimaging measurement QTL GWAS568967 (human)6e-12neuroimaging measurement153934202139342022Human
407091129GWAS740105_Hbrain volume measurement QTL GWAS740105 (human)6e-125brain volume measurementbrain morphological measurement (CMO:0000136)153934202139342022Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS557841_H GCST90385041 T1 FreeSurfer a2009s rh G&S subcentral volume 7,058 Chinese Han ancestry individuals G NR 8E-9 8.097 rs1080066 0.194329 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS558106_H GCST90385066 T1 FreeSurfer a2009s rh G precentral volume 7,058 Chinese Han ancestry individuals G NR 5E-10 9.302 rs1080066 0.209239 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS559312_H GCST90385550 T1 FreeSurfer BA rh BA3b exvivo area 7,058 Chinese Han ancestry individuals G NR 2E-11 10.699 rs1080066 0.210323 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS559316_H GCST90385552 T1 FreeSurfer BA rh BA4p exvivo area 7,058 Chinese Han ancestry individuals G NR 3E-9 8.523 rs1080066 0.191429 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS559436_H GCST90385580 T1 FreeSurfer BA rh BA4p exvivo volume 7,058 Chinese Han ancestry individuals G NR 2E-10 9.699 rs1080066 0.214669 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS568439_H GCST90385813 T1 FreeSurfer pial lh precentral area 7,058 Chinese Han ancestry individuals G NR 1E-7 7 rs1080066 0.166684 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS568967_H GCST90385780 T1 FreeSurfer DK rh precentral volume 7,058 Chinese Han ancestry individuals G NR 6E-12 11.222 rs1080066 0.220972 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS569815_H GCST90385679 T1 FreeSurfer DK lh precentral volume 7,058 Chinese Han ancestry individuals G NR 4E-8 7.398 rs1080066 0.176287 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS570352_H GCST90384013 T1 CAT volume R PrecentralGyrus 7,058 Chinese Han ancestry individuals G NR 4E-7 6.398 rs1080066 0.149767 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS573227_H GCST90385712 T1 FreeSurfer DK rh precentral area 7,058 Chinese Han ancestry individuals G NR 0.000002 5.699 rs1080066 0.146649 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS578367_H GCST90384277 T1 FreeSurfer DKT lh precentral volume 7,058 Chinese Han ancestry individuals G NR 5E-8 7.302 rs1080066 0.172902 neuroimaging measurement (EFO:0004346)
 PMID:38811844
None Available GCST90384308 T1 FreeSurfer DKT rh precentral area 7,058 Chinese Han ancestry individuals G NR 4E-7 6.398 rs1080066 0.157191 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS587602_H GCST90385845 T1 FreeSurfer pial rh precentral area 7,058 Chinese Han ancestry individuals G NR 1E-8 8 rs1080066 0.179608 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS626912_H GCST90384370 T1 FreeSurfer DKT rh precentral volume 7,058 Chinese Han ancestry individuals G NR 3E-13 12.523 rs1080066 0.231894 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS638656_H GCST90384844 T1 FreeSurfer a2009s lh G precentral volume 7,058 Chinese Han ancestry individuals G NR 2E-7 6.699 rs1080066 0.175404 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS737524_H GCST011617 Cortical surface area 18,617 European and African American ancestry individuals ? NR 2E-80 79.699 rs1080066 N/A cortical surface area measurement (EFO:0010736)
 PMID:32963231
GWAS738427_H GCST011617 Cortical surface area 18,617 European and African American ancestry individuals ? NR 1E-200 200 rs1080066 N/A cortical surface area measurement (EFO:0010736)
 PMID:32963231
GWAS740105_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 6E-125 124.222 rs1080066 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS1030731_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.9098 3E-184 183.523 rs1080066 124.7257 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS1030732_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.9103 3E-12 11.523 rs1080066 42.6451 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS1054039_H GCST010701 Cortical surface area (MOSTest) 26,502 European ancestry individuals ? NR 1E-242 242 rs1080066 N/A cortical surface area measurement (EFO:0010736)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS1055478_H GCST010700 Cortical thickness (MOSTest) 26,502 European ancestry individuals ? NR 7E-120 119.155 rs1080066 N/A cortical thickness (EFO:0004840)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS1056721_H GCST010703 Brain morphology (MOSTest) 26,502 European ancestry individuals ? NR 1E-305 305 rs1080066 N/A brain measurement (EFO:0004464)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS1064347_H GCST90003027 aparc-a2009s rh volume G-precentral 21,282 British ancestry individuals G 0.089 8E-62 61.097 rs1080066 0.281 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064348_H GCST90003043 aparc-a2009s rh volume S-central 21,282 British ancestry individuals G 0.089 3E-119 118.523 rs1080066 0.392 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064356_H GCST90003026 aparc-a2009s rh volume G-postcentral 21,282 British ancestry individuals G 0.089 2E-90 89.699 rs1080066 0.341 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1064678_H GCST90003162 aparc-pial lh area postcentral 21,282 British ancestry individuals G 0.089 1E-55 55 rs1080066 0.267 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064691_H GCST90003130 aparc-Desikan rh area precentral 21,282 British ancestry individuals G 0.089 4E-85 84.398 rs1080066 0.331 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064994_H GCST90003223 BA-exvivo rh area BA3a 21,281 British ancestry individuals G 0.089 4E-104 103.398 rs1080066 0.366 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064995_H GCST90003224 BA-exvivo rh area BA3b 21,281 British ancestry individuals G 0.089 6E-145 144.222 rs1080066 0.432 total cortical area measurement (EFO:0008381)
 PMID:33875891
None Available GCST90003226 BA-exvivo rh area BA4p 21,281 British ancestry individuals G 0.089 2E-90 89.699 rs1080066 0.341 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1064999_H GCST90003213 BA-exvivo lh area BA6 21,281 British ancestry individuals G 0.089 9E-29 28.046 rs1080066 0.189 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1065300_H GCST90003415 aparc-a2009s rh area S-central 21,282 British ancestry individuals G 0.089 1E-131 131 rs1080066 0.412 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1066620_H GCST90002952 aparc-a2009s lh volume G-postcentral 21,282 British ancestry individuals G 0.089 2E-91 90.699 rs1080066 0.343 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066622_H GCST90002969 aparc-a2009s lh volume S-central 21,282 British ancestry individuals G 0.089 5E-93 92.302 rs1080066 0.346 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066927_H GCST90002913 aparc-DKTatlas rh volume postcentral 21,282 British ancestry individuals G 0.089 1E-70 70 rs1080066 0.301 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066928_H GCST90002915 aparc-DKTatlas rh volume precentral 21,282 British ancestry individuals G 0.089 1E-77 77 rs1080066 0.316 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066932_H GCST90002851 BA-exvivo rh volume BA3a 21,281 British ancestry individuals G 0.089 2E-68 67.699 rs1080066 0.296 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066933_H GCST90002852 BA-exvivo rh volume BA3b 21,281 British ancestry individuals G 0.089 8E-165 164.097 rs1080066 0.461 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066934_H GCST90002853 BA-exvivo rh volume BA4a 21,281 British ancestry individuals G 0.089 1E-12 12 rs1080066 0.121 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066935_H GCST90002854 BA-exvivo rh volume BA4p 21,281 British ancestry individuals G 0.089 4E-53 52.398 rs1080066 0.26 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066936_H GCST90002855 BA-exvivo rh volume BA6 21,281 British ancestry individuals G 0.089 3E-21 20.523 rs1080066 0.161 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066939_H GCST90002822 aparc-Desikan rh volume postcentral 21,282 British ancestry individuals G 0.089 1E-84 84 rs1080066 0.33 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066940_H GCST90002824 aparc-Desikan rh volume precentral 21,282 British ancestry individuals G 0.089 2E-74 73.699 rs1080066 0.309 brain volume measurement (EFO:0006930)
 PMID:33875891
None Available GCST90002835 BA-exvivo lh volume BA1 21,281 British ancestry individuals G 0.089 2E-91 90.699 rs1080066 0.343 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066943_H GCST90002840 BA-exvivo lh volume BA4p 21,281 British ancestry individuals G 0.089 2E-39 38.699 rs1080066 0.223 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1066944_H GCST90002849 BA-exvivo rh volume BA1 21,281 British ancestry individuals G 0.089 1E-62 62 rs1080066 0.283 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS1067230_H GCST90003195 aparc-pial rh area postcentral 21,282 British ancestry individuals G 0.089 8E-53 52.097 rs1080066 0.259 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067231_H GCST90003197 aparc-pial rh area precentral 21,282 British ancestry individuals G 0.089 7E-89 88.155 rs1080066 0.338 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067838_H GCST90003365 aparc-a2009s lh area S-precentral-sup-part 21,282 British ancestry individuals G 0.089 2E-14 13.699 rs1080066 0.131 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067840_H GCST90003399 aparc-a2009s rh area G-precentral 21,282 British ancestry individuals G 0.089 1E-61 61 rs1080066 0.281 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067844_H GCST90003324 aparc-a2009s lh area G-postcentral 21,282 British ancestry individuals G 0.089 2E-18 17.699 rs1080066 0.149 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1067848_H GCST90002464 IDP T1 FAST ROIs R precentral gyrus 22,133 British ancestry individuals G 0.089 4E-57 56.398 rs1080066 0.264 brain volume measurement (EFO:0006930)
 PMID:33875891
None Available GCST90003287 aparc-DKTatlas rh area precentral 21,282 British ancestry individuals G 0.089 2E-91 90.699 rs1080066 0.343 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS1068453_H GCST90005420 rfMRI connectivity (ICA100 edge 567) 21,081 British ancestry individuals G 0.089 8E-13 12.097 rs1080066 0.122 brain connectivity measurement (EFO:0005210)
 PMID:33875891
Database Acc Id Source(s)
GWAS Catalog GCST90003130 GWAS Catalog

RGD Curation Notes
Note Type Note Reference