GWAS1060293_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1060293_H (phosphatidylcholine measurement QTL GWAS1060293 (human)) Homo sapiens

Symbol: GWAS1060293_H
Name: phosphatidylcholine measurement QTL GWAS1060293 (human)
RGD ID: 407411317
Trait: phosphatidylcholine measurement
LOD Score: Not Available
P Value: 4.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,462,743 - 58,462,744RGD_MAPPER_PIPELINEGRCh38
GRCh371558,754,942 - 58,754,943RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1060293_HHumanphosphatidylcholine measurement  IAGPrs79787170405850206 GWAS_CATALOGPMID:34503513
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736877LIPClipase C, hepatic type155843199158569844Human
11084824LIPC-AS1LIPC antisense RNA 1155843490158498735Human

Position Markers

Peak: (rs79787170)
Human AssemblyChrPosition (strand)Source
GRCh381558,462,743 - 58,462,744RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407396315GWAS1045291_Hlysophosphatidylethanolamine 18:0 measurement QTL GWAS1045291 (human)0.0000009blood lipid amount (VT:0003949)155846274358462744Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407399134GWAS1048110_Hlysophosphatidylethanolamine 18:0 measurement QTL GWAS1048110 (human)1e-09blood lipid amount (VT:0003949)155846274358462744Human
407396495GWAS1045471_Hlow density lipoprotein cholesterol measurement QTL GWAS1045471 (human)5e-26low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155846274358462744Human
407397905GWAS1046881_Hlysophosphatidylethanolamine 18:0 measurement QTL GWAS1046881 (human)0.000002blood lipid amount (VT:0003949)155846274358462744Human
407399283GWAS1048259_Hhigh density lipoprotein cholesterol measurement QTL GWAS1048259 (human)7e-21high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155846274358462744Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407411317GWAS1060293_Hphosphatidylcholine measurement QTL GWAS1060293 (human)4e-10phosphatidylcholine measurement155846274358462744Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1045291_H GCST90024208 Lysophosphatidylethanolamine (18:0) [sn1] levels 4,492 European ancestry individuals G NR 9E-7 6.046 rs79787170 0.362 lysophosphatidylethanolamine 18:0 measurement (EFO:0010367)
 PMID:35668104
GWAS1045471_H GCST90179148 Low-density lipoprotein levels (MTAG) 361,194 European ancestry individuals A NR 5E-26 25.302 rs79787170 0.04326 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36376304
GWAS1046881_H GCST90024209 Lysophosphatidylethanolamine (18:0) [sn2] levels 4,492 European ancestry individuals G NR 0.000002 5.699 rs79787170 0.353 lysophosphatidylethanolamine 18:0 measurement (EFO:0010367)
 PMID:35668104
GWAS1048110_H GCST90024823 Lysophosphatidylethanolamine (18:0) [sn1] levels 6,057 European ancestry individuals G NR 1E-9 9 rs79787170 N/A lysophosphatidylethanolamine 18:0 measurement (EFO:0010367)
 PMID:35668104
GWAS1048259_H GCST90179147 High-density lipoprotein levels (MTAG) 361,194 European ancestry individuals A NR 7E-21 20.155 rs79787170 0.07285 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36376304
GWAS1060293_H GCST90060273 Phosphatidylcholine_33:4_[M+H]1+/Phosphatidylethanolamine_36:4_[M+H]1+/Phosphatidate_38:5_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 4E-10 9.398 rs79787170 0.232326 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
Database Acc Id Source(s)
GWAS Catalog GCST90060273 GWAS Catalog

RGD Curation Notes
Note Type Note Reference