GWAS1054594_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1054594_H (glomerular filtration rate QTL GWAS1054594 (human)) Homo sapiens

Symbol: GWAS1054594_H
Name: glomerular filtration rate QTL GWAS1054594 (human)
RGD ID: 407405618
Trait: glomerular filtration rate
Measurement Type: glomerular filtration rate   (CMO:0000490)    
LOD Score: Not Available
P Value: 2.0E-26
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381545,467,143 - 45,467,144RGD_MAPPER_PIPELINEGRCh38
GRCh371545,759,341 - 45,759,342RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1054594_HHumanglomerular filtration rate  IAGPrs12592862405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1054594_HHumanglomerular filtration rate  IAGPrs12592862405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38646561SLC30A4-AS1SLC30A4 antisense RNA 1154544835445500048Human

Position Markers

Peak: (rs12592862)
Human AssemblyChrPosition (strand)Source
GRCh381545,467,143 - 45,467,144RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407405658GWAS1054634_Hcreatinine measurement QTL GWAS1054634 (human)3e-28creatinine measurementblood creatinine measurement (CMO:0000767)154546714345467144Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407405618GWAS1054594_Hglomerular filtration rate QTL GWAS1054594 (human)2e-26glomerular filtration rateglomerular filtration rate (CMO:0000490)154546714345467144Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1054594_H GCST90019506 Estimated glomerular filtration rate 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals T NR 2E-26 25.699 rs12592862 0.0634 glomerular filtration rate (EFO:0005208)
 PMID:33462484
GWAS1054634_H GCST90019502 Creatinine levels 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals T NR 3E-28 27.523 rs12592862 0.0657 creatinine measurement (EFO:0004518)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019506 GWAS Catalog

RGD Curation Notes
Note Type Note Reference