GWAS1028167_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1028167_H (serum albumin measurement QTL GWAS1028167 (human)) Homo sapiens

Symbol: GWAS1028167_H
Name: serum albumin measurement QTL GWAS1028167 (human)
RGD ID: 407379191
Trait: serum albumin measurement
Measurement Type: serum albumin level   (CMO:0000550)    
LOD Score: Not Available
P Value: 1.0E-22
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381543,641,743 - 43,641,744RGD_MAPPER_PIPELINEGRCh38
GRCh371543,933,941 - 43,933,942RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1028167_HHumanserum albumin level  IAGPrs139097404405850206Based on the EFO term IDGWAS_CATALOGPMID:34321204

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1028167_HHumanserum albumin measurement  IAGPrs139097404405850206 GWAS_CATALOGPMID:34321204
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1316921CATSPER2cation channel sperm associated 2154362850343648884Human
38604684PPIP5K1P1-CATSPER2PPIP5K1P1-CATSPER2 readthrough154363056243690031Human

Position Markers

Peak: (rs139097404)
Human AssemblyChrPosition (strand)Source
GRCh381543,641,743 - 43,641,744RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407266247GWAS915223_Hobsolete_red blood cell distribution width QTL GWAS915223 (human)5e-18obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)154364174343641744Human
407383050GWAS1032026_Hserum albumin measurement QTL GWAS1032026 (human)1e-15serum albumin measurementserum albumin level (CMO:0000550)154364174343641744Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407290222GWAS939198_Hhigh density lipoprotein cholesterol measurement QTL GWAS939198 (human)9e-26high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154364174343641744Human
407214670GWAS863646_Hacetate measurement QTL GWAS863646 (human)9e-10acetate measurement154364174343641744Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407388763GWAS1037739_Hserum gamma-glutamyl transferase measurement QTL GWAS1037739 (human)7e-22serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)154364174343641744Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407364347GWAS1013323_Hlipoprotein A measurement QTL GWAS1013323 (human)4e-28lipoprotein A measurement154364174343641744Human
407368088GWAS1017064_Hserum gamma-glutamyl transferase measurement QTL GWAS1017064 (human)9e-22serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)154364174343641744Human
407351160GWAS1000136_Hacetate measurement QTL GWAS1000136 (human)2e-09acetate measurement154364174343641744Human
407379191GWAS1028167_Hserum albumin measurement QTL GWAS1028167 (human)1e-22serum albumin measurementserum albumin level (CMO:0000550)154364174343641744Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
None Available GCST90002369 Red cell distribution width 531,774 European ancestry individuals T 0.976138 5E-18 17.302 rs139097404 0.054651 Red cell distribution width (EFO:0009188)
 PMID:32888493
GWAS863646_H GCST90269572 Acetate levels (UKB data field 23475) 88,306 European ancestry individuals C 0.0233307 9E-10 9.046 rs139097404 0.0971528 acetate measurement (EFO:0010112)
 PMID:36764567
GWAS939198_H GCST006611 HDL cholesterol 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals T 0.9746 9E-26 25.046 rs139097404 0.0988 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30275531
GWAS1000136_H GCST90092803 Acetate levels 115,050 European ancestry individuals T 0.976486 2E-9 8.699 rs139097404 0.0832288 acetate measurement (EFO:0010112)
 PMID:35213538
GWAS1013323_H GCST012232 Lipoprotein (a) levels 348,591 European ancestry individuals, 6,000 African ancestry individuals, 9,116 Asian ancestry individuals, 7,505 individuals T NR 4E-28 27.398 rs139097404 0.053097 lipoprotein A measurement (EFO:0006925)
 PMID:33730874
GWAS1017064_H GCST90013407 Liver enzyme levels (gamma-glutamyl transferase) 437,194 European ancestry individuals T 0.976384 9E-22 21.046 rs139097404 0.0161937 serum gamma-glutamyl transferase measurement (EFO:0004532)
 PMID:33972514
GWAS1028167_H GCST90027080 Albumin levels 158,000 British ancestry women C 0.02 1E-22 22 rs139097404 0.4 serum albumin measurement (EFO:0004535)
 PMID:34321204
GWAS1032026_H GCST90027081 Albumin levels 104,632 British ancestry post-menopausal women C 0.02 1E-15 15 rs139097404 0.4 serum albumin measurement (EFO:0004535)
 PMID:34321204
GWAS1037739_H GCST90428730 Gamma glutamyl transferase levels 875,069 European ancestry individuals C NR 7E-22 21.155 rs139097404 0.0163 serum gamma-glutamyl transferase measurement (EFO:0004532)
 PMID:38632349
Database Acc Id Source(s)
GWAS Catalog GCST90027080 GWAS Catalog

RGD Curation Notes
Note Type Note Reference