GWAS1002172_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1002172_H (BMI-adjusted waist-hip ratio QTL GWAS1002172 (human)) Homo sapiens

Symbol: GWAS1002172_H
Name: BMI-adjusted waist-hip ratio QTL GWAS1002172 (human)
RGD ID: 407353196
Trait: BMI-adjusted waist-hip ratio
LOD Score: Not Available
P Value: 8.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381541,823,549 - 41,823,550RGD_MAPPER_PIPELINEGRCh38
GRCh371542,115,747 - 42,115,748RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1002172_HHumanBMI-adjusted waist-hip ratio  IAGPrs3959569405850206 GWAS_CATALOGPMID:34021172
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1604640MAPKBP1mitogen-activated protein kinase binding protein 1154177448441827855Human

Position Markers

Peak: (rs3959569)
Human AssemblyChrPosition (strand)Source
GRCh381541,823,549 - 41,823,550RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407002579GWAS651555_HBMI-adjusted waist-hip ratio QTL GWAS651555 (human)0.000008BMI-adjusted waist-hip ratio154182354941823550Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407007531GWAS656507_HBMI-adjusted waist-hip ratio QTL GWAS656507 (human)0.000001BMI-adjusted waist-hip ratio154182354941823550Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407353196GWAS1002172_HBMI-adjusted waist-hip ratio QTL GWAS1002172 (human)8e-11BMI-adjusted waist-hip ratio154182354941823550Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407007599GWAS656575_HBMI-adjusted waist-hip ratio QTL GWAS656575 (human)2e-08BMI-adjusted waist-hip ratio154182354941823550Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS651555_H GCST007502 Waist-to-hip ratio adjusted for BMI (additive genetic model) up to 157,516 European ancestry women C 0.348 0.000008 5.097 rs3959569 0.0187 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30778226
GWAS656507_H GCST007483 Waist-to-hip ratio adjusted for BMI (additive genetic model) 288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals C 0.3148 0.000001 6 rs3959569 0.0141 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30778226
GWAS656575_H GCST007487 Waist-to-hip ratio adjusted for BMI (additive genetic model) 288,492 European ancestry individuals C 0.3489 2E-8 7.699 rs3959569 0.0173 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:30778226
GWAS1002172_H GCST90020027 Waist-hip index 219,872 British ancestry women C NR 8E-11 10.097 rs3959569 0.0195306 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST90020027 GWAS Catalog

RGD Curation Notes
Note Type Note Reference