GWAS981436_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS981436_H (triglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS981436 (human)) Homo sapiens

Symbol: GWAS981436_H
Name: triglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS981436 (human)
RGD ID: 407332460
Trait: triglyceride measurement, very low density lipoprotein cholesterol measurement
Measurement Type: blood triglyceride level   (CMO:0000118)    
blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,399,896 - 58,399,897RGD_MAPPER_PIPELINEGRCh38
GRCh371558,692,095 - 58,692,096RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS981436_HHumanblood triglyceride level  IAGPrs443401405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS981436_HHumanblood very low density lipoprotein cholesterol level  IAGPrs443401405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS981436_HHumantriglyceride measurement  IAGPrs443401405850206 GWAS_CATALOGPMID:35213538
GWAS981436_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs443401405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs443401)
Human AssemblyChrPosition (strand)Source
GRCh381558,399,896 - 58,399,897RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407182709GWAS831685_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS831685 (human)7e-11very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)155839989658399897Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407164211GWAS813187_Hphosphatidylethanolamine measurement QTL GWAS813187 (human)1e-11phosphatidylcholine measurement155839989658399897Human
407065417GWAS714393_Hlevel of Phosphatidylethanolamine (18:2_0:0) in blood serum QTL GWAS714393 (human)0.000007level of Phosphatidylethanolamine (18:2_0:0) in blood serum155839989658399897Human
407239743GWAS888719_Hapolipoprotein A 1 measurement, apolipoprotein B measurement QTL GWAS888719 (human)3e-11apolipoprotein A 1 measurement, apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)155839989658399897Human
407332460GWAS981436_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS981436 (human)4e-11triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155839989658399897Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS714393_H GCST90244403 Phosphatidylethanolamine (18:2_0:0) levels 4,642 European ancestry women G NR 0.000007 5.155 rs443401 0.1018 PMID:36193934
GWAS813187_H GCST90060665 Phosphatidylethanolamine(34:2)_[M+H]1+ levels 5,662 Pakistani ancestry individuals A NR 1E-11 11 rs443401 0.116 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060689 Phosphatidylethanolamine(36:4)_[M-H]1- levels 5,662 Pakistani ancestry individuals C NR 1E-11 11 rs443401 0.0667 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060690 Phosphatidylethanolamine(36:4)_[M+H]1+ levels 5,662 Pakistani ancestry individuals C NR 1E-11 11 rs443401 0.0329 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS831685_H GCST90092874 Total lipid levels in large VLDL 115,082 European ancestry individuals C 0.523543 7E-11 10.155 rs443401 0.0262252 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
None Available GCST90060692 Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 1E-11 11 rs443401 0.0808 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060738 Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals C NR 1E-11 11 rs443401 0.0465 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060696 Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals C NR 1E-11 11 rs443401 0.0892 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS888719_H GCST90092810 Ratio of apolipoprotein B to apolipoprotein A1 levels 115,082 European ancestry individuals C 0.523543 3E-11 10.523 rs443401 0.0274026 apolipoprotein A 1 measurement (EFO:0004614)
apolipoprotein B measurement (EFO:0004615)
 PMID:35213538
GWAS981436_H GCST90093026 Triglyceride levels in very large VLDL 115,082 European ancestry individuals C 0.523543 4E-11 10.398 rs443401 0.0263337 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90093026 GWAS Catalog

RGD Curation Notes
Note Type Note Reference