GWAS980352_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS980352_H (cholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS980352 (human)) Homo sapiens

Symbol: GWAS980352_H
Name: cholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS980352 (human)
RGD ID: 407331376
Trait: blood lipid amount   (VT:0003949)    
Measurement Type: blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 3.0E-27
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38162,498,066 - 62,498,067RGD_MAPPER_PIPELINEGRCh38
GRCh37162,963,737 - 62,963,738RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS980352_HHumanblood very low density lipoprotein cholesterol level  IAGPrs1002687405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS980352_HHumanblood lipid amount  IAGPrs1002687405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS980352_HHumancholesteryl ester measurement  IAGPrs1002687405850206 GWAS_CATALOGPMID:35213538
GWAS980352_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs1002687405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1352133DOCK7dedicator of cytokinesis 716245472662688386Human

Position Markers

Peak: (rs1002687)
Human AssemblyChrPosition (strand)Source
GRCh38162,498,066 - 62,498,067RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407040963GWAS689939_Hmonounsaturated fatty acids; 16:1, 18:1 measurement QTL GWAS689939 (human)4e-71monounsaturated fatty acids; 16:1, 18:1 measurement16249806662498067Human
407292741GWAS941717_Hlinoleic acid measurement QTL GWAS941717 (human)1e-93linoleic acid measurementblood free fatty acids level (CMO:0000117)16249806662498067Human
407240070GWAS889046_Hcholine measurement QTL GWAS889046 (human)5e-74choline measurement16249806662498067Human
407090183GWAS739159_Hfree cholesterol in small HDL measurement QTL GWAS739159 (human)5e-35free cholesterol in small HDL measurement 16249806662498067Human
407291264GWAS940240_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS940240 (human)2e-50free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407269903GWAS918879_Hcholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS918879 (human)7e-14blood lipid amount (VT:0003949)blood intermediate density lipoprotein cholesterol level (CMO:0001562)16249806662498067Human
407244811GWAS893787_Hhigh density lipoprotein cholesterol measurement QTL GWAS893787 (human)3e-29high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407039890GWAS688866_Hlinoleic acid measurement QTL GWAS688866 (human)5e-64linoleic acid measurementblood free fatty acids level (CMO:0000117)16249806662498067Human
407189908GWAS838884_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS838884 (human)3e-106triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407333014GWAS981990_Hfatty acid measurement QTL GWAS981990 (human)7e-84fatty acid measurement16249806662498067Human
407291412GWAS940388_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS940388 (human)7e-81phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407343316GWAS992292_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS992292 (human)4e-80triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407041691GWAS690667_Hsaturated fatty acids measurement QTL GWAS690667 (human)8e-59saturated fatty acids measurement 16249806662498067Human
407307741GWAS956717_Hpolyunsaturated fatty acid measurement QTL GWAS956717 (human)6e-118milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)16249806662498067Human
407266076GWAS915052_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS915052 (human)1e-131triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407328985GWAS977961_Hfatty acid measurement QTL GWAS977961 (human)5e-113fatty acid measurement16249806662498067Human
2314561GLUCO47_HGlucose level QTL 47 (human)1.1Glucose level14477336070773360Human
407308901GWAS957877_Hlinoleic acid measurement QTL GWAS957877 (human)2e-95linoleic acid measurementblood free fatty acids level (CMO:0000117)16249806662498067Human
407309348GWAS958324_Htotal cholesterol measurement QTL GWAS958324 (human)3e-25total cholesterol measurementblood total cholesterol level (CMO:0000051)16249806662498067Human
1578620LDLPS20_HLow density lipoprotein particle size QTL 21 (human)2.040.00046LDL particle size15253110578531105Human
407328738GWAS977714_Hlipoprotein measurement QTL GWAS977714 (human)6e-35lipoprotein measurementblood lipoprotein measurement (CMO:0002690)16249806662498067Human
407282083GWAS931059_Hword reading QTL GWAS931059 (human)0.0000009word reading16249806662498067Human
407255203GWAS904179_Hfatty acid measurement QTL GWAS904179 (human)9e-103fatty acid measurement16249806662498067Human
407318497GWAS967473_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS967473 (human)2e-64lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407321647GWAS970623_Homega-6 polyunsaturated fatty acid measurement QTL GWAS970623 (human)2e-103omega-6 polyunsaturated fatty acid measurement16249806662498067Human
407255854GWAS904830_Homega-6 polyunsaturated fatty acid measurement QTL GWAS904830 (human)3e-105omega-6 polyunsaturated fatty acid measurement16249806662498067Human
407030443GWAS679419_Hfatty acid measurement QTL GWAS679419 (human)2e-78fatty acid measurement16249806662498067Human
407029547GWAS678523_Homega-6 polyunsaturated fatty acid measurement QTL GWAS678523 (human)8e-72omega-6 polyunsaturated fatty acid measurement16249806662498067Human
407329710GWAS978686_Hlipoprotein measurement, phospholipid measurement QTL GWAS978686 (human)1e-71lipoprotein measurement, phospholipid measurementblood lipoprotein measurement (CMO:0002690)16249806662498067Human
407238380GWAS887356_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS887356 (human)2e-62triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)16249806662498067Human
407311596GWAS960572_Hfree cholesterol measurement QTL GWAS960572 (human)2e-34free cholesterol measurementblood cholesterol level (CMO:0002280)16249806662498067Human
407248877GWAS897853_Hphosphatidylinositol measurement QTL GWAS897853 (human)8e-41phosphatidylinositol measurement16249806662498067Human
407242730GWAS891706_Hlipid measurement, intermediate density lipoprotein measurement QTL GWAS891706 (human)2e-17lipid measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)16249806662498067Human
407280233GWAS929209_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS929209 (human)2e-48phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human
407040114GWAS689090_Hpolyunsaturated fatty acid measurement QTL GWAS689090 (human)2e-81milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)16249806662498067Human
407314487GWAS963463_Hesterified cholesterol measurement QTL GWAS963463 (human)1e-21esterified cholesterol measurement16249806662498067Human
1578602LDLPS21_HLow density lipoprotein particle size QTL 21 (human)2.050.00037LDL particle size15253110578531105Human
407099184GWAS748160_Hcholesteryl esters to total lipids in small LDL percentage QTL GWAS748160 (human)2e-85cholesteryl esters to total lipids in small LDL percentage 16249806662498067Human
407286066GWAS935042_Hphospholipid measurement QTL GWAS935042 (human)1e-86phospholipid measurement16249806662498067Human
407327025GWAS976001_Hlipid measurement, lipoprotein measurement QTL GWAS976001 (human)2e-68lipid measurement, lipoprotein measurementblood lipoprotein measurement (CMO:0002690)16249806662498067Human
407331376GWAS980352_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS980352 (human)3e-27blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)16249806662498067Human
407288575GWAS937551_Hphospholipid measurement QTL GWAS937551 (human)1e-90phospholipid measurement16249806662498067Human
1578594LDLPS19_HLow density lipoprotein particle size QTL 19 (human)2.560.00009LDL particle size15253110578531105Human
407291196GWAS940172_Hhigh density lipoprotein cholesterol measurement QTL GWAS940172 (human)1e-30high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)16249806662498067Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS678523_H GCST90269542 Omega-6 fatty acids levels (UKB data field 23445) 88,268 European ancestry individuals G 0.354334 8E-72 71.097 rs1002687 0.0866176 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:36764567
GWAS679419_H GCST90269539 Total fatty acids levels (UKB data field 23442) 88,268 European ancestry individuals G 0.354334 2E-78 77.699 rs1002687 0.0917852 fatty acid measurement (EFO:0005110)
 PMID:36764567
GWAS688866_H GCST90269546 Linoleic acid levels (UKB data field 23449) 88,268 European ancestry individuals G 0.354334 5E-64 63.302 rs1002687 0.0818625 linoleic acid measurement (EFO:0006807)
 PMID:36764567
GWAS689090_H GCST90269543 Polyunsaturated fatty acids levels (UKB data field 23446) 88,268 European ancestry individuals G 0.354334 2E-81 80.699 rs1002687 0.0921406 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:36764567
GWAS689939_H GCST90269544 Monounsaturated fatty acids levels (UKB data field 23447) 88,268 European ancestry individuals G 0.354334 4E-71 70.398 rs1002687 0.0872989 monounsaturated fatty acids (EFO:0022187)
 PMID:36764567
GWAS690667_H GCST90269545 Saturated fatty acids levels (UKB data field 23448) 88,268 European ancestry individuals G 0.354334 8E-59 58.097 rs1002687 0.0789463 saturated fatty acids measurement (EFO:0022304)
 PMID:36764567
GWAS739159_H GCST90269674 Free cholesterol in small HDL (UKB data field 23577) 88,329 European ancestry individuals G 0.354298 5E-35 34.302 rs1002687 0.0598263 free cholesterol in small HDL measurement (EFO:0022270)
 PMID:36764567
GWAS748160_H GCST90269723 Cholesteryl esters to total lipids in small LDL percentage (UKB data field 23626) 88,329 European ancestry individuals G 0.354298 2E-85 84.699 rs1002687 0.0970025 cholesteryl esters to total lipids in small LDL percentage (EFO:0022255)
 PMID:36764567
GWAS838884_H GCST90092854 Triglyceride levels in large HDL 115,082 European ancestry individuals G 0.355237 3E-106 105.523 rs1002687 0.0897256 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS887356_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals G 0.355237 2E-62 61.699 rs1002687 0.0701714 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS889046_H GCST90092812 Total cholines levels 115,006 European ancestry individuals G 0.355261 5E-74 73.302 rs1002687 0.0736931 choline measurement (EFO:0010116)
 PMID:35213538
GWAS891706_H GCST90092837 Total lipid levels in IDL 115,082 European ancestry individuals G 0.355237 2E-17 16.699 rs1002687 0.0353527 lipid measurement (EFO:0004529)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS893787_H GCST90092826 Concentration of HDL particles 115,082 European ancestry individuals G 0.355237 3E-29 28.523 rs1002687 0.0454523 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS897853_H GCST90060912 Phosphatidylinositol(36:2)_[M-H]1- levels 5,662 Pakistani ancestry individuals G NR 8E-41 40.097 rs1002687 0.0649 phosphatidylinositol measurement (EFO:0010230)
 PMID:34503513
GWAS904179_H GCST90092928 Monounsaturated fatty acid levels 115,006 European ancestry individuals G 0.355261 9E-103 102.046 rs1002687 0.0914582 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS904830_H GCST90092933 Omega-6 fatty acid levels 115,006 European ancestry individuals G 0.355261 3E-105 104.523 rs1002687 0.0917563 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35213538
GWAS915052_H GCST90092829 Triglyceride levels in HDL 115,082 European ancestry individuals G 0.355237 1E-131 131 rs1002687 0.102926 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS918879_H GCST90092833 Cholesteryl ester levels in IDL 115,082 European ancestry individuals G 0.355237 7E-14 13.155 rs1002687 0.0312199 cholesteryl ester measurement (EFO:0010351)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS929209_H GCST90092900 Phospholipid levels in medium HDL 115,082 European ancestry individuals G 0.355237 2E-48 47.699 rs1002687 0.0589005 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS931059_H GCST90104462 Word reading 27,180 European ancestry individuals, 1,238 Hispanic or African American individuals, 5,541 individuals A 0.6213 9E-7 6.046 rs1002687 0.0417 word reading (EFO:0005300)
 PMID:35998220
GWAS935042_H GCST90092937 Phosphatidylcholine levels 115,006 European ancestry individuals G 0.355261 1E-86 86 rs1002687 0.0794946 phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS937551_H GCST90092938 Phosphoglycerides levels 115,006 European ancestry individuals G 0.355261 1E-90 90 rs1002687 0.0821824 phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS940172_H GCST90092951 Concentration of small HDL particles 115,082 European ancestry individuals G 0.355237 1E-30 30 rs1002687 0.0496256 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS940240_H GCST90092948 Free cholesterol levels in small HDL 115,082 European ancestry individuals G 0.355237 2E-50 49.699 rs1002687 0.0630859 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS940388_H GCST90092952 Phospholipid levels in small HDL 115,082 European ancestry individuals G 0.355237 7E-81 80.155 rs1002687 0.0813532 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS941717_H GCST90133363 Linoleic acid levels 114,999 European ancestry individuals G 0.36 1E-93 93 rs1002687 0.087 linoleic acid measurement (EFO:0006807)
 PMID:35692035
GWAS956717_H GCST90092939 Polyunsaturated fatty acid levels 115,006 European ancestry individuals G 0.355261 6E-118 117.222 rs1002687 0.0966459 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:35213538
GWAS957877_H GCST90092880 Linoleic acid levels 115,006 European ancestry individuals G 0.355261 2E-95 94.699 rs1002687 0.087773 linoleic acid measurement (EFO:0006807)
 PMID:35213538
GWAS958324_H GCST90092985 Total cholesterol levels 115,082 European ancestry individuals G 0.355237 3E-25 24.523 rs1002687 0.0433781 total cholesterol measurement (EFO:0004574)
 PMID:35213538
GWAS960572_H GCST90092988 Total free cholesterol levels 115,082 European ancestry individuals G 0.355237 2E-34 33.699 rs1002687 0.0516096 free cholesterol measurement (EFO:0008591)
 PMID:35213538
GWAS963463_H GCST90092986 Total esterified cholesterol levels 115,082 European ancestry individuals G 0.355237 1E-21 21 rs1002687 0.0397458 esterified cholesterol measurement (EFO:0008589)
 PMID:35213538
GWAS967473_H GCST90092950 Total lipid levels in small HDL 115,082 European ancestry individuals G 0.355237 2E-64 63.699 rs1002687 0.0728806 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS970623_H GCST90133364 Total omega-6 fatty acid levels 114,999 European ancestry individuals G 0.36 2E-103 102.699 rs1002687 0.091 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35692035
GWAS976001_H GCST90092989 Total lipid levels in lipoprotein particles 115,082 European ancestry individuals G 0.355237 2E-68 67.699 rs1002687 0.0740928 lipid measurement (EFO:0004529)
lipoprotein measurement (EFO:0004732)
 PMID:35213538
GWAS977714_H GCST90092990 Total concentration of lipoprotein particles 115,082 European ancestry individuals G 0.355237 6E-35 34.222 rs1002687 0.0500326 lipoprotein measurement (EFO:0004732)
 PMID:35213538
GWAS977961_H GCST90092987 Total fatty acid levels 115,006 European ancestry individuals G 0.355261 5E-113 112.302 rs1002687 0.096121 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS978686_H GCST90092991 Total phospholipid levels in lipoprotein particles 115,082 European ancestry individuals G 0.355237 1E-71 71 rs1002687 0.0734295 lipoprotein measurement (EFO:0004732)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS980352_H GCST90093030 Cholesteryl ester levels in very small VLDL 115,082 European ancestry individuals G 0.355237 3E-27 26.523 rs1002687 0.0449101 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS981990_H GCST90092980 Saturated fatty acid levels 115,006 European ancestry individuals G 0.355261 7E-84 83.155 rs1002687 0.0824895 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS992292_H GCST90093014 Triglyceride levels in very large HDL 115,082 European ancestry individuals G 0.355237 4E-80 79.398 rs1002687 0.0796752 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90093030 GWAS Catalog

RGD Curation Notes
Note Type Note Reference