GWAS979834_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS979834_H (non-high density lipoprotein cholesterol measurement QTL GWAS979834 (human)) Homo sapiens

Symbol: GWAS979834_H
Name: non-high density lipoprotein cholesterol measurement QTL GWAS979834 (human)
RGD ID: 407330858
Trait: non-high density lipoprotein cholesterol measurement
Measurement Type: blood non-high density lipoprotein cholesterol level   (CMO:0003967)    
serum non-high density lipoprotein cholesterol level   (CMO:0003841)    
LOD Score: Not Available
P Value: 5.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh384109,717,668 - 109,717,669RGD_MAPPER_PIPELINEGRCh38
GRCh374110,638,824 - 110,638,825RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS979834_HHumanblood non-high density lipoprotein cholesterol level  IAGPrs114816312405850206Based on the EFO term IDGWAS_CATALOGPMID:34887591
GWAS979834_HHumanserum non-high density lipoprotein cholesterol level  IAGPrs114816312405850206Based on the EFO term IDGWAS_CATALOGPMID:34887591

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS979834_HHumannon-high density lipoprotein cholesterol measurement  IAGPrs114816312405850206 GWAS_CATALOGPMID:34887591
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1312232PLA2G12Aphospholipase A2 group XIIA4109709989109730070Human

Position Markers

Peak: (rs114816312)
Human AssemblyChrPosition (strand)Source
GRCh384109,717,668 - 109,717,669RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643256BW127_HBody Weight QTL 127 (human)1.310.007Body weightbody mass index4106319694132319694Human
407333221GWAS982197_Htriglyceride measurement QTL GWAS982197 (human)1e-44triglyceride measurementblood triglyceride level (CMO:0000118)4109717668109717669Human
407129927GWAS778903_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS778903 (human)1e-09triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4109717668109717669Human
407216161GWAS865137_Hapolipoprotein A 1 measurement QTL GWAS865137 (human)3e-67apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)4109717668109717669Human
407312866GWAS961842_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS961842 (human)4e-08total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)4109717668109717669Human
407296480GWAS945456_Htestosterone measurement QTL GWAS945456 (human)2e-11testosterone measurementserum testosterone level (CMO:0000568)4109717668109717669Human
407287297GWAS936273_Hhigh density lipoprotein cholesterol measurement QTL GWAS936273 (human)1e-25high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4109717668109717669Human
407028491GWAS677467_Hsex hormone-binding globulin measurement QTL GWAS677467 (human)5e-25sex hormone-binding globulin measurement4109717668109717669Human
407324718GWAS973694_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS973694 (human)1e-08very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)4109717668109717669Human
407330858GWAS979834_Hnon-high density lipoprotein cholesterol measurement QTL GWAS979834 (human)5e-12non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)4109717668109717669Human
407217067GWAS866043_Hsex hormone-binding globulin measurement QTL GWAS866043 (human)1e-34sex hormone-binding globulin measurement4109717668109717669Human
407302793GWAS951769_Hsex hormone-binding globulin measurement QTL GWAS951769 (human)9e-41sex hormone-binding globulin measurement4109717668109717669Human
407202218GWAS851194_Hsex hormone-binding globulin measurement QTL GWAS851194 (human)2e-52sex hormone-binding globulin measurement4109717668109717669Human
407202250GWAS851226_Hlipoprotein A measurement QTL GWAS851226 (human)1e-11lipoprotein A measurement4109717668109717669Human
407206762GWAS855738_Htriglyceride measurement QTL GWAS855738 (human)1e-38high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4109717668109717669Human
407221237GWAS870213_Hsex hormone-binding globulin measurement QTL GWAS870213 (human)6e-26sex hormone-binding globulin measurement4109717668109717669Human
407316790GWAS965766_Hnon-high density lipoprotein cholesterol measurement QTL GWAS965766 (human)2e-13non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)4109717668109717669Human
407213591GWAS862567_Hhigh density lipoprotein cholesterol measurement QTL GWAS862567 (human)2e-44high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4109717668109717669Human
407337855GWAS986831_Htriglyceride measurement QTL GWAS986831 (human)9e-33triglyceride measurementblood triglyceride level (CMO:0000118)4109717668109717669Human
407182328GWAS831304_Hmean corpuscular volume QTL GWAS831304 (human)4e-11mean corpuscular volumemean corpuscular volume (CMO:0000038)4109717668109717669Human
407089565GWAS738541_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS738541 (human)6e-12triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)4109717668109717669Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS677467_H GCST90239822 Sex hormone-binding globulin levels 188,443 British ancestry women ? NR 5E-25 24.302 rs114816312 0.177208 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:36653534
GWAS738541_H GCST90302042 Triglycerides to total lipids ratio in medium HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0082 6E-12 11.222 rs114816312 0.1957 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS778903_H GCST90302090 Triglycerides to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.0082 1E-9 9 rs114816312 0.1714 triglycerides:total lipids ratio (EFO:0020947)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS831304_H GCST90002397 Mean spheric corpuscular volume 408,112 British individuals T 0.00749200000000005 4E-11 10.398 rs114816312 0.08593651 mean corpuscular volume (EFO:0004526)
 PMID:32888494
GWAS851194_H GCST90025958 Sex hormone-binding globulin levels 397,043 European ancestry individuals ? NR 2E-52 51.699 rs114816312 0.171122 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:34226706
GWAS851226_H GCST90025993 Lipoprotein (a) levels 348,806 European ancestry individuals ? NR 1E-11 11 rs114816312 0.0618169 lipoprotein A measurement (EFO:0006925)
 PMID:34226706
GWAS855738_H GCST90025957 Triglyceride levels 437,532 European ancestry individuals ? NR 1E-38 38 rs114816312 0.145485 triglyceride measurement (EFO:0004530)
 PMID:34226706
None Available GCST012232 Lipoprotein (a) levels 348,591 European ancestry individuals, 6,000 African ancestry individuals, 9,116 Asian ancestry individuals, 7,505 individuals C NR 1E-11 11 rs114816312 0.064087 lipoprotein A measurement (EFO:0006925)
 PMID:33730874
GWAS862567_H GCST90025956 HDL cholesterol levels 400,754 European ancestry individuals ? NR 2E-44 43.699 rs114816312 0.158841 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34226706
GWAS865137_H GCST90025955 Apolipoprotein A1 levels 398,508 European ancestry individuals ? NR 3E-67 66.523 rs114816312 0.20303 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:34226706
GWAS866043_H GCST90012106 Sex hormone-binding globulin levels adjusted for BMI 188,908 European ancestry women T 0.007750000000000035 1E-34 34 rs114816312 0.0826054 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS870213_H GCST90012107 Sex hormone-binding globulin levels 189,473 European ancestry women T 0.007750000000000035 6E-26 25.222 rs114816312 0.0816229 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
None Available GCST90239649 High density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 1E-38 38 rs114816312 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS936273_H GCST90239652 High density lipoprotein cholesterol levels 1,320,016 European ancestry individuals T 0.00601751 1E-25 25 rs114816312 0.125672 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS945456_H GCST90012113 Total testosterone levels 194,453 European ancestry men T 0.007476999999999956 2E-11 10.699 rs114816312 0.119397 testosterone measurement (EFO:0004908)
 PMID:32042192
None Available GCST90012110 Sex hormone-binding globulin levels adjusted for BMI 368,929 European ancestry individuals T 0.007611000000000034 2E-52 51.699 rs114816312 0.0716861 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS951769_H GCST90012111 Sex hormone-binding globulin levels 370,125 European ancestry individuals T 0.007611000000000034 9E-41 40.046 rs114816312 0.0716992 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS961842_H GCST90093016 Cholesterol levels in very large VLDL 115,082 European ancestry individuals C 0.992388 4E-8 7.398 rs114816312 0.127494 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS965766_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-13 12.699 rs114816312 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS973694_H GCST90093025 Phospholipids to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.992348 1E-8 8 rs114816312 0.135774 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS979834_H GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals T 0.00607468 5E-12 11.302 rs114816312 0.0881442 non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS982197_H GCST90239661 Triglyceride levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 1E-44 44 rs114816312 N/A triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS986831_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals T 0.00610471 9E-33 32.046 rs114816312 0.134231 triglyceride measurement (EFO:0004530)
 PMID:34887591
Database Acc Id Source(s)
GWAS Catalog GCST90239670 GWAS Catalog

RGD Curation Notes
Note Type Note Reference