GWAS974568_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS974568_H (serum gamma-glutamyl transferase measurement QTL GWAS974568 (human)) Homo sapiens

Symbol: GWAS974568_H
Name: serum gamma-glutamyl transferase measurement QTL GWAS974568 (human)
RGD ID: 407325592
Trait: serum gamma-glutamyl transferase measurement
Measurement Type: serum gamma-glutamyltransferase activity level   (CMO:0002241)    
LOD Score: Not Available
P Value: 8.0E-39
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,090,531 - 16,090,532RGD_MAPPER_PIPELINEGRCh38
GRCh37116,417,026 - 16,417,027RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS974568_HHumanserum gamma-glutamyltransferase activity level  IAGPrs28429281405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS974568_HHumanserum gamma-glutamyl transferase measurement  IAGPrs28429281405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs28429281)
Human AssemblyChrPosition (strand)Source
GRCh38116,090,531 - 16,090,532RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407191120GWAS840096_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS840096 (human)8e-10aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)11609053116090532Human
407171644GWAS820620_Hserum alanine aminotransferase measurement QTL GWAS820620 (human)9e-11serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)11609053116090532Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407325592GWAS974568_Hserum gamma-glutamyl transferase measurement QTL GWAS974568 (human)8e-39serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)11609053116090532Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS820620_H GCST90019492 Alanine aminotransferase levels 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals A NR 9E-11 10.046 rs28429281 0.0156 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:33462484
GWAS840096_H GCST90019498 Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals A NR 8E-10 9.097 rs28429281 0.0148 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:33462484
GWAS974568_H GCST90019507 Gamma glutamyl transferase levels 342,339 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals A NR 8E-39 38.097 rs28429281 0.0314 serum gamma-glutamyl transferase measurement (EFO:0004532)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019507 GWAS Catalog

RGD Curation Notes
Note Type Note Reference