GWAS972702_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS972702_H (low density lipoprotein cholesterol measurement QTL GWAS972702 (human)) Homo sapiens

Symbol: GWAS972702_H
Name: low density lipoprotein cholesterol measurement QTL GWAS972702 (human)
RGD ID: 407323726
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 2.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh383132,498,859 - 132,498,860RGD_MAPPER_PIPELINEGRCh38
GRCh373132,217,703 - 132,217,704RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS972702_HHumanblood low density lipoprotein cholesterol level  IAGPrs113177823405850206Based on the EFO term IDGWAS_CATALOGPMID:34594039

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS972702_HHumanlow density lipoprotein cholesterol measurement  IAGPrs113177823405850206 GWAS_CATALOGPMID:34594039
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1317589DNAJC13DnaJ heat shock protein family (Hsp40) member C133132417502132539032Human

Position Markers

Peak: (rs113177823)
Human AssemblyChrPosition (strand)Source
GRCh383132,498,859 - 132,498,860RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406916883GWAS565859_Hlow density lipoprotein cholesterol measurement QTL GWAS565859 (human)1e-18low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)3132498859132498860Human
406918359GWAS567335_Hlow density lipoprotein cholesterol measurement QTL GWAS567335 (human)8e-20low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)3132498859132498860Human
407336753GWAS985729_Htotal cholesterol measurement QTL GWAS985729 (human)2e-14total cholesterol measurementblood total cholesterol level (CMO:0000051)3132498859132498860Human
407323726GWAS972702_Hlow density lipoprotein cholesterol measurement QTL GWAS972702 (human)2e-12low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)3132498859132498860Human
407336028GWAS985004_Huric acid measurement QTL GWAS985004 (human)8e-17uric acid measurementblood uric acid level (CMO:0000501)3132498859132498860Human
407288522GWAS937498_Hserum albumin measurement QTL GWAS937498 (human)7e-15serum albumin measurementserum albumin level (CMO:0000550)3132498859132498860Human
406923118GWAS572094_Hapolipoprotein B measurement QTL GWAS572094 (human)9e-19apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)3132498859132498860Human
407323880GWAS972856_Hlow density lipoprotein cholesterol measurement QTL GWAS972856 (human)2e-08low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)3132498859132498860Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS565859_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals G 0.945866 1E-18 18 rs113177823 0.0410816 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS567335_H GCST010204 Low density lipoprotein cholesterol levels 324,708 British ancestry individuals ? NR 8E-20 19.097 rs113177823 0.052 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32154731
GWAS572094_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals G 0.945903 9E-19 18.046 rs113177823 0.0411203 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS937498_H GCST90018945 Serum albumin levels 315,268 European ancestry individuals, 120,539 East Asian ancestry individuals A NR 7E-15 14.155 rs113177823 0.0428 serum albumin measurement (EFO:0004535)
 PMID:34594039
GWAS972702_H GCST90018961 LDL cholesterol 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals A NR 2E-12 11.699 rs113177823 0.037 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34594039
GWAS972856_H GCST90179148 Low-density lipoprotein levels (MTAG) 361,194 European ancestry individuals A NR 2E-8 7.699 rs113177823 0.0173 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36376304
GWAS985004_H GCST90018977 Serum uric acid levels 343,836 European ancestry individuals, 129,405 East Asian ancestry individuals A NR 8E-17 16.097 rs113177823 0.0378 uric acid measurement (EFO:0004761)
 PMID:34594039
GWAS985729_H GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals A NR 2E-14 13.699 rs113177823 0.0396 total cholesterol measurement (EFO:0004574)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018961 GWAS Catalog

RGD Curation Notes
Note Type Note Reference