GWAS964500_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS964500_H (QT interval QTL GWAS964500 (human)) Homo sapiens

Symbol: GWAS964500_H
Name: QT interval QTL GWAS964500 (human)
RGD ID: 407315524
Trait: QT interval
Measurement Type: QT interval   (CMO:0000235)    
LOD Score: Not Available
P Value: 2.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,720,670 - 10,720,671RGD_MAPPER_PIPELINEGRCh38
GRCh37110,780,727 - 10,780,728RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS964500_HHumanQT interval  IAGPrs706007405850206Based on the EFO term IDGWAS_CATALOGPMID:36050321

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS964500_HHumanQT interval  IAGPrs706007405850206 GWAS_CATALOGPMID:36050321
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
QT interval  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1606535CASZ1castor zinc finger 111063660410796646Human

Position Markers

Peak: (rs706007)
Human AssemblyChrPosition (strand)Source
GRCh38110,720,670 - 10,720,671RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407315524GWAS964500_HQT interval QTL GWAS964500 (human)2e-12QT intervalQT interval (CMO:0000235)11072067010720671Human
407330220GWAS979196_HQT interval QTL GWAS979196 (human)1e-10QT intervalQT interval (CMO:0000235)11072067010720671Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS964500_H GCST90179153 QT interval 252,730 European ancestry, African ancestry, Hispanic or Latin American, South East Asian ancestry, South Asian ancestry individuals A 0.8518 2E-12 11.699 rs706007 0.0339 QT interval (EFO:0004682)
 PMID:36050321
GWAS979196_H GCST90165291 QT interval 86,165 European ancestry individuals, 13,975 Hispanic or Latin American individuals, 5,034 East Asian ancestry individuals, 8,457 African American individuals, 310 South Asian ancestry individuals, 1,631 Asian ancestry individuals, 1,370 Native Hawaiian ancestry individuals, 226 Native American ancestry individuals, 364 individuals A 0.115 1E-10 10 rs706007 0.96 QT interval (EFO:0004682)
 PMID:36271874
Database Acc Id Source(s)
GWAS Catalog GCST90179153 GWAS Catalog

RGD Curation Notes
Note Type Note Reference