GWAS964220_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS964220_H (very low density lipoprotein particle size measurement QTL GWAS964220 (human)) Homo sapiens

Symbol: GWAS964220_H
Name: very low density lipoprotein particle size measurement QTL GWAS964220 (human)
RGD ID: 407315244
Trait: very low density lipoprotein particle size measurement
Measurement Type: blood very low density lipoprotein particle diameter   (CMO:0002694)    
LOD Score: Not Available
P Value: 2.0E-26
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,282,767 - 58,282,768RGD_MAPPER_PIPELINEGRCh38
GRCh371558,574,966 - 58,574,967RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS964220_HHumanblood very low density lipoprotein particle diameter  IAGPrs56050415405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS964220_HHumanvery low density lipoprotein particle size measurement  IAGPrs56050415405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs56050415)
Human AssemblyChrPosition (strand)Source
GRCh381558,282,767 - 58,282,768RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407165701GWAS814677_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS814677 (human)4e-42blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407279111GWAS928087_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS928087 (human)2e-18triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407266279GWAS915255_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS915255 (human)3e-47total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407191138GWAS840114_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS840114 (human)3e-15phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407315244GWAS964220_Hvery low density lipoprotein particle size measurement QTL GWAS964220 (human)2e-26very low density lipoprotein particle size measurementblood very low density lipoprotein particle diameter (CMO:0002694)155828276758282768Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407289494GWAS938470_Hphospholipid measurement QTL GWAS938470 (human)4e-60phospholipid measurement155828276758282768Human
407182487GWAS831463_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS831463 (human)9e-67triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155828276758282768Human
407345683GWAS994659_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS994659 (human)1e-49blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407242780GWAS891756_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS891756 (human)5e-53free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407197241GWAS846217_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS846217 (human)3e-49free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407316091GWAS965067_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS965067 (human)8e-50total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155828276758282768Human
407332888GWAS981864_Htotal cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS981864 (human)2e-61total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155828276758282768Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS814677_H GCST90092846 Cholesteryl ester levels in large HDL 115,082 European ancestry individuals T 0.814611 4E-42 41.398 rs56050415 0.0651492 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS831463_H GCST90092867 Triglycerides to total lipids ratio in large LDL 115,082 European ancestry individuals T 0.814611 9E-67 66.046 rs56050415 0.090808 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS840114_H GCST90092853 Phospholipids to total lipids ratio in large HDL 115,082 European ancestry individuals T 0.814611 3E-15 14.523 rs56050415 0.0412763 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS846217_H GCST90092849 Free cholesterol to total lipids ratio in large HDL 115,082 European ancestry individuals T 0.814611 3E-49 48.523 rs56050415 0.074324 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS891756_H GCST90092824 Free cholesterol levels in HDL 115,082 European ancestry individuals T 0.814611 5E-53 52.302 rs56050415 0.0735604 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS915255_H GCST90092844 Cholesterol levels in large HDL 115,082 European ancestry individuals T 0.814611 3E-47 46.523 rs56050415 0.0689033 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS928087_H GCST90132636 Triglyceride levels in very large HDL 21,536 European ancestry individuals ? NR 2E-18 17.699 rs56050415 0.1263201 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:27005778
GWAS938470_H GCST90092937 Phosphatidylcholine levels 115,006 European ancestry individuals T 0.814609 4E-60 59.398 rs56050415 0.0828789 phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS964220_H GCST90093002 Average diameter for VLDL particles 115,082 European ancestry individuals T 0.814611 2E-26 25.699 rs56050415 0.0537542 very low density lipoprotein particle size measurement (EFO:0008594)
 PMID:35213538
GWAS965067_H GCST90093004 Cholesterol levels in very large HDL 115,082 European ancestry individuals T 0.814611 8E-50 49.097 rs56050415 0.072597 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS981864_H GCST90093028 Cholesterol levels in very small VLDL 115,082 European ancestry individuals T 0.814611 2E-61 60.699 rs56050415 0.0869339 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS994659_H GCST90093006 Cholesteryl ester levels in very large HDL 115,082 European ancestry individuals T 0.814611 1E-49 49 rs56050415 0.0719407 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90093002 GWAS Catalog

RGD Curation Notes
Note Type Note Reference