GWAS949044_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS949044_H (C-reactive protein measurement QTL GWAS949044 (human)) Homo sapiens

Symbol: GWAS949044_H
Name: C-reactive protein measurement QTL GWAS949044 (human)
RGD ID: 407300068
Trait: C-reactive protein measurement
Measurement Type: blood C-reactive protein level   (CMO:0003160)    
LOD Score: Not Available
P Value: 3.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381551,453,080 - 51,453,081RGD_MAPPER_PIPELINEGRCh38
GRCh371551,745,277 - 51,745,278RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS949044_HHumanblood C-reactive protein level  IAGPrs4774590405850206Based on the EFO term IDGWAS_CATALOGPMID:30388399

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS949044_HHumanC-reactive protein measurement  IAGPrs4774590405850206 GWAS_CATALOGPMID:30388399
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1347338DMXL2Dmx like 2155144779151622771Human

Position Markers

Peak: (rs4774590)
Human AssemblyChrPosition (strand)Source
GRCh381551,453,080 - 51,453,081RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407300068GWAS949044_HC-reactive protein measurement QTL GWAS949044 (human)3e-08C-reactive protein measurementblood C-reactive protein level (CMO:0003160)155145308051453081Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS949044_H GCST007614 C-reactive protein levels up to 92,771 European ancestry males, up to 113,387 European ancestry females A 0.35 3E-8 7.523 rs4774590 0.022 C-reactive protein measurement (EFO:0004458)
 PMID:30388399
Database Acc Id Source(s)
GWAS Catalog GCST007614 GWAS Catalog

RGD Curation Notes
Note Type Note Reference