GWAS911282_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS911282_H (brain volume measurement QTL GWAS911282 (human)) Homo sapiens

Symbol: GWAS911282_H
Name: brain volume measurement QTL GWAS911282 (human)
RGD ID: 407262306
Trait: brain volume measurement
Measurement Type: brain morphological measurement   (CMO:0000136)    
LOD Score: Not Available
P Value: 5.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381539,341,703 - 39,341,704RGD_MAPPER_PIPELINEGRCh38
GRCh371539,633,904 - 39,633,905RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS911282_HHumanbrain morphological measurement  IAGPrs2033939405850206Based on the EFO term IDGWAS_CATALOGPMID:33875891

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS911282_HHumanbrain volume measurement  IAGPrs2033939405850206 GWAS_CATALOGPMID:33875891
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38627269LOC105370777uncharacterized LOC105370777153886480639421060Human

Position Markers

Peak: (rs2033939)
Human AssemblyChrPosition (strand)Source
GRCh381539,341,703 - 39,341,704RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407180103GWAS829079_Hcortical surface area measurement QTL GWAS829079 (human)8e-23cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934170339341704Human
407260227GWAS909203_Hcortical thickness QTL GWAS909203 (human)6e-48cortical thickness153934170339341704Human
407042376GWAS691352_Hcortical surface area measurement QTL GWAS691352 (human)1e-15cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934170339341704Human
407180104GWAS829080_Hcortical surface area measurement QTL GWAS829080 (human)8e-09cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934170339341704Human
406911822GWAS560798_Hneuroimaging measurement QTL GWAS560798 (human)0.0000003neuroimaging measurement153934170339341704Human
407263560GWAS912536_Htotal cortical area measurement QTL GWAS912536 (human)3e-14total cortical area measurement153934170339341704Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407260759GWAS909735_Hcortical thickness QTL GWAS909735 (human)2e-54cortical thickness153934170339341704Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407258846GWAS907822_Hcortical thickness QTL GWAS907822 (human)4e-43cortical thickness153934170339341704Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407262426GWAS911402_Hbrain volume measurement QTL GWAS911402 (human)6e-24brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407262310GWAS911286_Hbrain volume measurement QTL GWAS911286 (human)3e-15brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407154022GWAS802998_Hbrain volume measurement QTL GWAS802998 (human)8e-11brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407258596GWAS907572_Hcortical thickness QTL GWAS907572 (human)1e-30cortical thickness153934170339341704Human
407258597GWAS907573_Hcortical thickness QTL GWAS907573 (human)5e-32cortical thickness153934170339341704Human
407258594GWAS907570_Hcortical thickness QTL GWAS907570 (human)6e-50cortical thickness153934170339341704Human
407262306GWAS911282_Hbrain volume measurement QTL GWAS911282 (human)5e-11brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407258595GWAS907571_Hcortical thickness QTL GWAS907571 (human)2e-82cortical thickness153934170339341704Human
407014126GWAS663102_Hbrain volume measurement QTL GWAS663102 (human)4e-23brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407261034GWAS910010_Htotal cortical area measurement QTL GWAS910010 (human)2e-21total cortical area measurement153934170339341704Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
407258600GWAS907576_Hcortical thickness QTL GWAS907576 (human)3e-53cortical thickness153934170339341704Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
407261681GWAS910657_Hbrain volume measurement QTL GWAS910657 (human)1e-13brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407014136GWAS663112_Hbrain volume measurement QTL GWAS663112 (human)4e-133brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407262077GWAS911053_Htotal cortical area measurement QTL GWAS911053 (human)2e-15total cortical area measurement153934170339341704Human
407264251GWAS913227_Htotal cortical area measurement QTL GWAS913227 (human)4e-13total cortical area measurement153934170339341704Human
407268985GWAS917961_Hbrain measurement QTL GWAS917961 (human)4e-230brain measurementbrain measurement (CMO:0000911)153934170339341704Human
407261319GWAS910295_Hcortical thickness QTL GWAS910295 (human)6e-19cortical thickness153934170339341704Human
407261060GWAS910036_Hcortical thickness QTL GWAS910036 (human)2e-43cortical thickness153934170339341704Human
406910211GWAS559187_Hneuroimaging measurement QTL GWAS559187 (human)0.000005neuroimaging measurement153934170339341704Human
407261061GWAS910037_Hcortical thickness QTL GWAS910037 (human)4e-90cortical thickness153934170339341704Human
407259650GWAS908626_Htotal cortical area measurement QTL GWAS908626 (human)5e-31total cortical area measurement153934170339341704Human
407178761GWAS827737_Hbrain volume measurement QTL GWAS827737 (human)2e-79brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407158152GWAS807128_Hbrain volume measurement QTL GWAS807128 (human)2e-81brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
407261323GWAS910299_Hcortical thickness QTL GWAS910299 (human)1e-83cortical thickness153934170339341704Human
406939026GWAS588002_Hneuroimaging measurement QTL GWAS588002 (human)0.000004neuroimaging measurement153934170339341704Human
406908054GWAS557030_Hneuroimaging measurement QTL GWAS557030 (human)0.0000006neuroimaging measurement153934170339341704Human
407269649GWAS918625_Hbrain measurement QTL GWAS918625 (human)1e-206brain measurementbrain measurement (CMO:0000911)153934170339341704Human
407259935GWAS908911_Htotal cortical area measurement QTL GWAS908911 (human)4e-22total cortical area measurement153934170339341704Human
407259931GWAS908907_Htotal cortical area measurement QTL GWAS908907 (human)1e-14total cortical area measurement153934170339341704Human
406912417GWAS561393_Hneuroimaging measurement QTL GWAS561393 (human)0.000002neuroimaging measurement153934170339341704Human
407265444GWAS914420_Hbrain volume measurement QTL GWAS914420 (human)7e-44brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
406967715GWAS616691_Hbrain connectivity measurement QTL GWAS616691 (human)1e-115brain connectivity measurement153934170339341704Human
406967970GWAS616946_Hbrain connectivity measurement QTL GWAS616946 (human)3e-46brain connectivity measurement153934170339341704Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
406912420GWAS561396_Hneuroimaging measurement QTL GWAS561396 (human)0.000008neuroimaging measurement153934170339341704Human
407259954GWAS908930_Hcortical thickness QTL GWAS908930 (human)1e-60cortical thickness153934170339341704Human
407014071GWAS663047_Hbrain volume measurement QTL GWAS663047 (human)8e-14brain volume measurementbrain morphological measurement (CMO:0000136)153934170339341704Human
406985271GWAS634247_Hcortical surface area measurement QTL GWAS634247 (human)2e-53cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934170339341704Human
407014325GWAS663301_Hcortical thickness QTL GWAS663301 (human)8e-136cortical thickness153934170339341704Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS557030_H GCST90384769 T1 FreeSurfer a2009s lh G postcentral thickness 7,058 Chinese Han ancestry individuals A NR 6E-7 6.222 rs2033939 0.366201 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS559187_H GCST90385533 T1 FreeSurfer BA lh BA1 exvivo volume 7,058 Chinese Han ancestry individuals A NR 0.000005 5.302 rs2033939 0.299292 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS560798_H GCST90385564 T1 FreeSurfer BA rh BA3b exvivo thickness 7,058 Chinese Han ancestry individuals A NR 3E-7 6.523 rs2033939 0.376146 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS561393_H GCST90385519 T1 FreeSurfer BA lh BA1 exvivo thickness 7,058 Chinese Han ancestry individuals A NR 0.000002 5.699 rs2033939 0.347195 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS561396_H GCST90385522 T1 FreeSurfer BA lh BA3b exvivo thickness 7,058 Chinese Han ancestry individuals A NR 0.000008 5.097 rs2033939 0.331161 neuroimaging measurement (EFO:0004346)
 PMID:38811844
None Available GCST90385643 T1 FreeSurfer DK lh postcentral thickness 7,058 Chinese Han ancestry individuals A NR 0.000002 5.699 rs2033939 0.349283 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS588002_H GCST90384244 T1 FreeSurfer DKT lh postcentral thickness 7,058 Chinese Han ancestry individuals A NR 0.000004 5.398 rs2033939 0.346245 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS616691_H GCST90165318 Edge-level brain connectivity (multivariate analysis) 30,810 British ancestry individuals G 0.919709 1E-115 115 rs2033939 22.864235 brain connectivity measurement (EFO:0005210)
 PMID:36800424
GWAS616946_H GCST90165317 Node-level brain connectivity (multivariate analysis) 30,810 British ancestry individuals G 0.919709 3E-46 45.523 rs2033939 14.273774 brain connectivity measurement (EFO:0005210)
 PMID:36800424
GWAS634247_H GCST011617 Cortical surface area 18,617 European and African American ancestry individuals ? NR 2E-53 52.699 rs2033939 N/A cortical surface area measurement (EFO:0010736)
 PMID:32963231
None Available GCST90384843 T1 FreeSurfer a2009s lh G postcentral volume 7,058 Chinese Han ancestry individuals A NR 3E-7 6.523 rs2033939 0.348526 neuroimaging measurement (EFO:0004346)
 PMID:38811844
GWAS663047_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 8E-14 13.097 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS663102_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 4E-23 22.398 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS663112_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 4E-133 132.398 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS663301_H GCST011618 Cortical thickness 22,163 European and African American ancestry individuals ? NR 8E-136 135.097 rs2033939 N/A cortical thickness (EFO:0004840)
 PMID:32963231
GWAS691352_H GCST90271794 Motor premotor area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 1E-15 15 rs2033939 0.1042 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS802998_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 8E-11 10.097 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS807128_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 2E-81 80.699 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS827737_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 2E-79 78.699 rs2033939 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS829079_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.0801 8E-23 22.097 rs2033939 18.21615 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS829080_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.0802 8E-9 8.097 rs2033939 3.012083 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS907570_H GCST90003500 aparc-Desikan rh thickness postcentral 21,282 British ancestry individuals A 0.081 6E-50 49.222 rs2033939 0.264 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS907571_H GCST90003513 BA-exvivo lh thickness BA1 21,281 British ancestry individuals A 0.081 2E-82 81.699 rs2033939 0.342 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS907572_H GCST90003514 BA-exvivo lh thickness BA2 21,281 British ancestry individuals A 0.081 1E-30 30 rs2033939 0.205 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS907573_H GCST90003516 BA-exvivo lh thickness BA3b 21,281 British ancestry individuals A 0.081 5E-32 31.302 rs2033939 0.21 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS907576_H GCST90003527 BA-exvivo rh thickness BA1 21,281 British ancestry individuals A 0.081 3E-53 52.523 rs2033939 0.273 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS907822_H GCST90003528 BA-exvivo rh thickness BA2 21,281 British ancestry individuals A 0.081 4E-43 42.398 rs2033939 0.245 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS908626_H GCST90003374 aparc-a2009s rh area G+S-subcentral 21,282 British ancestry individuals A 0.081 5E-31 30.302 rs2033939 0.206 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS908907_H GCST90003322 aparc-a2009s lh area G-pariet-inf-Supramar 21,282 British ancestry individuals A 0.081 1E-14 14 rs2033939 0.138 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS908911_H GCST90003396 aparc-a2009s rh area G-pariet-inf-Supramar 21,282 British ancestry individuals A 0.081 4E-22 21.398 rs2033939 0.172 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS908930_H GCST90003530 BA-exvivo rh thickness BA3b 21,281 British ancestry individuals A 0.081 1E-60 60 rs2033939 0.292 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS909203_H GCST90003560 aparc-DKTatlas lh thickness postcentral 21,282 British ancestry individuals A 0.081 6E-48 47.222 rs2033939 0.259 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS909735_H GCST90003466 aparc-Desikan lh thickness postcentral 21,282 British ancestry individuals A 0.081 2E-54 53.699 rs2033939 0.276 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS910010_H GCST90003363 aparc-a2009s lh area S-postcentral 21,282 British ancestry individuals A 0.081 2E-21 20.699 rs2033939 0.169 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS910036_H GCST90003591 aparc-DKTatlas rh thickness postcentral 21,282 British ancestry individuals A 0.081 2E-43 42.699 rs2033939 0.245 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS910037_H GCST90003630 aparc-a2009s lh thickness G-postcentral 21,282 British ancestry individuals A 0.081 4E-90 89.398 rs2033939 0.357 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS910295_H GCST90003669 aparc-a2009s lh thickness S-postcentral 21,282 British ancestry individuals A 0.081 6E-19 18.222 rs2033939 0.158 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS910299_H GCST90003704 aparc-a2009s rh thickness G-postcentral 21,282 British ancestry individuals A 0.081 1E-83 83 rs2033939 0.344 cortical thickness (EFO:0004840)
 PMID:33875891
GWAS910657_H GCST90002993 aparc-a2009s lh volume S-precentral-sup-part 21,282 British ancestry individuals A 0.081 1E-13 13 rs2033939 0.132 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS911053_H GCST90003263 aparc-DKTatlas lh area supramarginal 21,282 British ancestry individuals A 0.081 2E-15 14.699 rs2033939 0.141 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS911282_H GCST90003050 aparc-a2009s rh volume S-front-inf 21,282 British ancestry individuals A 0.081 5E-11 10.302 rs2033939 0.117 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS911286_H GCST90003067 aparc-a2009s rh volume S-precentral-sup-part 21,282 British ancestry individuals A 0.081 3E-15 14.523 rs2033939 0.141 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS911402_H GCST90002841 BA-exvivo lh volume BA6 21,281 British ancestry individuals A 0.081 6E-24 23.222 rs2033939 0.18 brain volume measurement (EFO:0006930)
 PMID:33875891
None Available GCST90003171 aparc-pial lh area supramarginal 21,282 British ancestry individuals A 0.081 1E-14 14 rs2033939 0.138 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS912536_H GCST90003103 aparc-Desikan lh area supramarginal 21,282 British ancestry individuals A 0.081 3E-14 13.523 rs2033939 0.136 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS913227_H GCST90003208 BA-exvivo lh area BA2 21,281 British ancestry individuals A 0.081 4E-13 12.398 rs2033939 0.129 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS914420_H GCST90003002 aparc-a2009s rh volume G+S-subcentral 21,282 British ancestry individuals A 0.081 7E-44 43.155 rs2033939 0.247 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS917961_H GCST90131904 Whole brain restricted isotropic diffusion (multivariate analysis) 23,543 European ancestry individuals ? NR 4E-230 229.398 rs2033939 N/A brain measurement (EFO:0004464)
 PMID:35505052
GWAS918625_H GCST90131906 Whole brain free water diffusion (multivariate analysis) 23,543 European ancestry individuals ? NR 1E-206 206 rs2033939 N/A brain measurement (EFO:0004464)
 PMID:35505052
None Available GCST90399898 Regional cortical thickness (postcentral) 34,573 European ancestry individuals A NR 6E-81 80.222 rs2033939 N/A cortical thickness (EFO:0004840)
 PMID:38890310
Database Acc Id Source(s)
GWAS Catalog GCST90003050 GWAS Catalog

RGD Curation Notes
Note Type Note Reference