GWAS908998_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS908998_H (low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS908998 (human)) Homo sapiens

Symbol: GWAS908998_H
Name: low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS908998 (human)
RGD ID: 407260022
Trait: low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 8.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386159,764,119 - 159,764,120RGD_MAPPER_PIPELINEGRCh38
GRCh376160,185,151 - 160,185,152RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS908998_HHumanblood low density lipoprotein cholesterol level  IAGPrs5015801405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS908998_HHumanlow density lipoprotein cholesterol measurement  IAGPrs5015801405850206 GWAS_CATALOGPMID:35213538
GWAS908998_HHumanphospholipids:total lipids ratio  IAGPrs5015801405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1354229ACAT2acetyl-CoA acetyltransferase 26159762045159779112Human

Position Markers

Peak: (rs5015801)
Human AssemblyChrPosition (strand)Source
GRCh386159,764,119 - 159,764,120RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407260022GWAS908998_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS908998 (human)8e-09low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6159764119159764120Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407294179GWAS943155_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS943155 (human)3e-10low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6159764119159764120Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS908998_H GCST90092913 Phospholipids to total lipids ratio in medium LDL 115,082 European ancestry individuals A 0.982074 8E-9 8.097 rs5015801 0.096073 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS943155_H GCST90092907 Cholesteryl esters to total lipids ratio in medium LDL 115,082 European ancestry individuals A 0.982074 3E-10 9.523 rs5015801 0.104784 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092913 GWAS Catalog

RGD Curation Notes
Note Type Note Reference