GWAS904128_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS904128_H (inflammatory bowel disease QTL GWAS904128 (human)) Homo sapiens

Symbol: GWAS904128_H
Name: inflammatory bowel disease QTL GWAS904128 (human)
RGD ID: 407255152
Trait: inflammatory bowel disease
LOD Score: Not Available
P Value: 1.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381560,777,789 - 60,777,790RGD_MAPPER_PIPELINEGRCh38
GRCh371561,069,988 - 61,069,989RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318175RORARAR related orphan receptor A156048828461229302Human

Position Markers

Peak: (rs11071559)
Human AssemblyChrPosition (strand)Source
GRCh381560,777,789 - 60,777,790RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407270724GWAS919700_Hasthma QTL GWAS919700 (human)7e-20asthma156077778960777790Human
407017249GWAS666225_HInhalant adrenergic use measurement QTL GWAS666225 (human)2e-12Inhalant adrenergic use measurement156077778960777790Human
407110625GWAS759601_Hrespiratory system disease QTL GWAS759601 (human)3e-13respiratory system disease156077778960777790Human
407211392GWAS860368_Hchildhood onset asthma QTL GWAS860368 (human)3e-15childhood onset asthma156077778960777790Human
407182466GWAS831442_Hasthma QTL GWAS831442 (human)1e-18asthma156077778960777790Human
407258241GWAS907217_Hasthma QTL GWAS907217 (human)2e-19asthma156077778960777790Human
407128013GWAS776989_Hasthma QTL GWAS776989 (human)0.0000001asthma156077778960777790Human
407271500GWAS920476_Hallergic disease, age at onset QTL GWAS920476 (human)5e-11allergic disease, age at onset156077778960777790Human
407271181GWAS920157_Hallergic disease QTL GWAS920157 (human)4e-11allergic disease156077778960777790Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407019468GWAS668444_Hage of onset of asthma QTL GWAS668444 (human)3e-22age of onset of asthma156077778960777790Human
407201835GWAS850811_Hasthma QTL GWAS850811 (human)4e-18asthma156077778960777790Human
407178901GWAS827877_Hasthma, age at onset QTL GWAS827877 (human)0.0000008asthma, age at onset156077778960777790Human
407263351GWAS912327_Hasthma QTL GWAS912327 (human)0.000005asthma156077778960777790Human
407252946GWAS901922_Hasthma QTL GWAS901922 (human)2e-27asthma156077778960777790Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407299187GWAS948163_Hchildhood onset asthma QTL GWAS948163 (human)2e-37childhood onset asthma156077778960777790Human
407273331GWAS922307_Hasthma QTL GWAS922307 (human)5e-37asthma156077778960777790Human
407052885GWAS701861_Heosinophil count QTL GWAS701861 (human)5e-14eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)156077778960777790Human
407255152GWAS904128_Hinflammatory bowel disease QTL GWAS904128 (human)1e-09inflammatory bowel disease156077778960777790Human
407298641GWAS947617_Hasthma QTL GWAS947617 (human)4e-24asthma156077778960777790Human
407300414GWAS949390_Hasthma, age at onset QTL GWAS949390 (human)0.000003asthma, age at onset156077778960777790Human
407120126GWAS769102_Heosinophil count QTL GWAS769102 (human)1e-14eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)156077778960777790Human
407269020GWAS917996_Hasthma QTL GWAS917996 (human)3e-14asthma156077778960777790Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS666225_H GCST007941 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls T 0.128561 2E-12 11.699 rs11071559 0.09462308 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:31015401
GWAS668444_H GCST90255668 Age of onset of adult onset asthma 56,744 European ancestry cases, 674,014 European ancestry controls ? NR 3E-22 21.523 rs11071559 0.089541 PMID:36778051
GWAS701861_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals T 0.13051 5E-14 13.302 rs11071559 0.0222 eosinophil count (EFO:0004842)
 PMID:32888493
None Available GCST90309345 Respiratory disease (confirmatory factor analysis Factor 11) 360,406 European ancestry individuals ? NR 2E-28 27.699 rs11071559 N/A respiratory system disease (EFO:0000684)
 PMID:38965376
GWAS759601_H GCST007076 Respiratory diseases approximately 459,000 European ancestry individuals ? NR 3E-13 12.523 rs11071559 N/A respiratory system disease (EFO:0000684)
 PMID:30595370
GWAS769102_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 1E-14 14 rs11071559 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS776989_H GCST000804 Asthma 10,365 cases, 16,110 controls C 0.86 1E-7 7 rs11071559 1.18 PMID:20860503
GWAS827877_H GCST008838 Asthma (time to onset) 5,462 European ancestry cases, 8,424 European ancestry controls C 0.85 8E-7 6.097 rs11071559 1.16 age at onset (EFO:0004847)
 PMID:27130862
GWAS831442_H GCST90018795 Asthma 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls T NR 1E-18 18 rs11071559 0.0833 PMID:34594039
GWAS850811_H GCST90014325 Asthma 56,167 White-British ancestry cases, 352,255 White-British ancestry controls T 0.128023221080157 4E-18 17.398 rs11071559 0.08468739 PMID:34103634
GWAS860368_H GCST007995 Asthma (childhood onset) 9,433 British ancestry cases, 318,237 British ancestry controls C 0.872 3E-15 14.523 rs11071559 1.205 PMID:31036433
GWAS901922_H GCST010042 Asthma 64,538 European ancestry cases, 239,321 European ancestry controls C 0.859587 2E-27 26.699 rs11071559 1.0986217 PMID:32296059
GWAS904128_H GCST90292538 Inflammatory bowel disease 14,393 East Asian ancestry cases, 15,456 East Asian ancestry controls, 30,713 European ancestry cases, 338,106 European ancestry controls ? NR 1E-9 9 rs11071559 0.0817 inflammatory bowel disease (EFO:0003767)
 PMID:37156999
GWAS907217_H GCST009798 Asthma 16,247 European ancestry cases, 346,486 European ancestry controls, 52,942 cases, 355,713 controls C 0.87197 2E-19 18.699 rs11071559 1.0895382 PMID:31959851
GWAS912327_H GCST007994 Asthma (age of onset) 37,846 British ancestry individuals C 0.872 0.000005 5.302 rs11071559 0.958 PMID:31036433
GWAS917996_H GCST90018575 Asthma 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls T 0.231406462 3E-14 13.523 rs11071559 0.12352817 PMID:34594039
GWAS919700_H GCST009720 Asthma 41,926 European ancestry cases, 239,773 European ancestry controls T 0.1281 7E-20 19.155 rs11071559 N/A PMID:31361310
GWAS920157_H GCST010984 Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) 477,968 European ancestry individuals C 0.877 4E-11 10.398 rs11071559 0.042 PMID:32603359
GWAS920476_H GCST010985 Allergic disease (asthma, hay fever and/or eczema) (age of onset) 117,130 European ancestry individuals C 0.877 5E-11 10.302 rs11071559 0.042 age at onset (EFO:0004847)
 PMID:32603359
GWAS922307_H GCST010043 Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls C 0.86 5E-37 36.302 rs11071559 N/A PMID:32296059
GWAS947617_H GCST007798 Asthma 40,544 European ancestry cases, 300,671 European ancestry controls C NR 4E-24 23.398 rs11071559 1.107 PMID:30929738
GWAS948163_H GCST007800 Asthma (childhood onset) 13,962 European ancestry cases, 300,671 European ancestry controls ? NR 2E-37 36.699 rs11071559 1.145 PMID:30929738
GWAS949390_H GCST007797 Asthma onset (childhood vs adult) 13,962 European ancestry childhood onset cases, 14,873 European ancestry adult onset cases C 0.868 0.000003 5.523 rs11071559 1.073 age at onset (EFO:0004847)
 PMID:30929738
None Available GCST90446792 Crohn's disease 7,372 East Asian ancestry cases, 15,456 East Asian ancestry controls, 13,501 European ancestry cases, 331,263 European ancestry controls ? NR 9E-7 6.046 rs11071559 0.0919 Crohn's disease (EFO:0000384)
 PMID:37156999
Database Acc Id Source(s)
GWAS Catalog GCST90292538 GWAS Catalog

RGD Curation Notes
Note Type Note Reference