GWAS898267_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS898267_H (cholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS898267 (human)) Homo sapiens

Symbol: GWAS898267_H
Name: cholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS898267 (human)
RGD ID: 407249291
Trait: blood lipid amount   (VT:0003949)    
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
blood total cholesterol level   (CMO:0000051)    
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812112,697,726 - 112,697,727RGD_MAPPER_PIPELINEGRCh38
GRCh3712113,135,531 - 113,135,532RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS898267_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs2384049405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS898267_HHumanblood total cholesterol level  IAGPrs2384049405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS898267_HHumanblood lipid amount  IAGPrs2384049405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1347244RPH3Arabphilin 3A12112575236112898881Human

Position Markers

Peak: (rs2384049)
Human AssemblyChrPosition (strand)Source
GRCh3812112,697,726 - 112,697,727RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559125SPSL2_HSerum P-selectin level QTL 2 (human)2.59Serum P-selectin level1289897665115897665Human
1298449UAE2_HUrinary albumin excretion QTL 2 (human)20.005Urinary albumin excretionurine albumin:creatinine ratio (ACR)12102836889128836889Human
1643258BW205_HBody weight QTL 205 (human)4.080.00001Body fat amountpercent body fat1296630114122630114Human
1643452BW104_HBody weight QTL 104 (human)1.890.005Body fat amountabdominal visceral12102395874128395874Human
1357361BW37_HBody weight QTL 37 (human)4.080.00001Body fat amount12102836889116423339Human
407328322GWAS977298_Hlipoprotein measurement, phospholipid measurement QTL GWAS977298 (human)3e-08lipoprotein measurement, phospholipid measurementblood lipoprotein measurement (CMO:0002690)12112697726112697727Human
407309325GWAS958301_Hesterified cholesterol measurement QTL GWAS958301 (human)7e-10esterified cholesterol measurement12112697726112697727Human
407249291GWAS898267_Hcholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS898267 (human)1e-08blood lipid amount (VT:0003949)blood total cholesterol level (CMO:0000051)12112697726112697727Human
407256084GWAS905060_Homega-6 polyunsaturated fatty acid measurement QTL GWAS905060 (human)1e-09total cholesterol measurementblood total cholesterol level (CMO:0000051)12112697726112697727Human
407330675GWAS979651_Hsphingomyelin measurement QTL GWAS979651 (human)8e-10sphingomyelin measurement12112697726112697727Human
407311602GWAS960578_Hfree cholesterol measurement QTL GWAS960578 (human)9e-09free cholesterol measurementblood cholesterol level (CMO:0002280)12112697726112697727Human
1643264BW195_HBody weight QTL 195 (human)0.0151Body weightBMI1289897665115897665Human
407343452GWAS992428_Hurate measurement QTL GWAS992428 (human)4e-11urate measurementblood uric acid level (CMO:0000501)12112697726112697727Human
1357387BW58_HBody weight QTL 58 (human)2.30.0001Body weightfat free mass after exercise training1289438856115438856Human
1358827MULTSCL22_HMultiple sclerosis susceptibility QTL 22 (human)Multiple sclerosis susceptibility1289897665115897665Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS898267_H GCST90092833 Cholesteryl ester levels in IDL 115,082 European ancestry individuals A 0.2826 1E-8 8 rs2384049 0.0255795 cholesteryl ester measurement (EFO:0010351)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS905060_H GCST90092933 Omega-6 fatty acid levels 115,006 European ancestry individuals A 0.282617 1E-9 9 rs2384049 0.0275047 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35213538
None Available GCST90092831 Cholesterol levels in IDL 115,082 European ancestry individuals A 0.2826 1E-8 8 rs2384049 0.0254079 total cholesterol measurement (EFO:0004574)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS958301_H GCST90092986 Total esterified cholesterol levels 115,082 European ancestry individuals A 0.2826 7E-10 9.155 rs2384049 0.0275214 esterified cholesterol measurement (EFO:0008589)
 PMID:35213538
GWAS960578_H GCST90092988 Total free cholesterol levels 115,082 European ancestry individuals A 0.2826 9E-9 8.046 rs2384049 0.0260451 free cholesterol measurement (EFO:0008591)
 PMID:35213538
None Available GCST90092985 Total cholesterol levels 115,082 European ancestry individuals A 0.2826 1E-9 9 rs2384049 0.027254 total cholesterol measurement (EFO:0004574)
 PMID:35213538
GWAS977298_H GCST90092991 Total phospholipid levels in lipoprotein particles 115,082 European ancestry individuals A 0.2826 3E-8 7.523 rs2384049 0.0243774 lipoprotein measurement (EFO:0004732)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS979651_H GCST90092982 Sphingomyelin levels 115,006 European ancestry individuals A 0.282617 8E-10 9.097 rs2384049 0.0266197 sphingomyelin measurement (EFO:0010118)
 PMID:35213538
GWAS992428_H GCST90319906 Serum urate levels 677,373 European ancestry individuals A NR 4E-11 10.398 rs2384049 0.02 urate measurement (EFO:0004531)
 PMID:38658550
Database Acc Id Source(s)
GWAS Catalog GCST90092831 GWAS Catalog
  GCST90092833 GWAS Catalog

RGD Curation Notes
Note Type Note Reference