GWAS891741_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS891741_H (testosterone measurement QTL GWAS891741 (human)) Homo sapiens

Symbol: GWAS891741_H
Name: testosterone measurement QTL GWAS891741 (human)
RGD ID: 407242765
Trait: testosterone measurement
Measurement Type: serum testosterone level   (CMO:0000568)    
LOD Score: Not Available
P Value: 6.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,775,835 - 21,775,836RGD_MAPPER_PIPELINEGRCh38
GRCh37122,102,328 - 22,102,329RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS891741_HHumanserum testosterone level  IAGPrs10799713405850206Based on the EFO term IDGWAS_CATALOGPMID:35192695

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS891741_HHumantestosterone measurement  IAGPrs10799713405850206 GWAS_CATALOGPMID:35192695
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1351270USP48ubiquitin specific peptidase 4812167829821783149Human

Position Markers

Peak: (rs10799713)
Human AssemblyChrPosition (strand)Source
GRCh38121,775,835 - 21,775,836RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407270116GWAS919092_Htestosterone measurement QTL GWAS919092 (human)0.000001testosterone measurementserum testosterone level (CMO:0000568)12177583521775836Human
407006825GWAS655801_Htestosterone measurement QTL GWAS655801 (human)9e-16testosterone measurementserum testosterone level (CMO:0000568)12177583521775836Human
407242765GWAS891741_Htestosterone measurement QTL GWAS891741 (human)0.0000006testosterone measurementserum testosterone level (CMO:0000568)12177583521775836Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS655801_H GCST90012112 Total testosterone levels 230,454 European ancestry women G 0.21159 9E-16 15.046 rs10799713 0.0270994 testosterone measurement (EFO:0004908)
 PMID:32042192
GWAS891741_H GCST90104272 Testosterone levels 182,648 European ancestry individuals G 0.219647 6E-7 6.222 rs10799713 0.0201065 testosterone measurement (EFO:0004908)
 PMID:35192695
None Available GCST90104296 Testosterone levels 4,229 African ancestry individuals, 182,648 European ancestry individuals ? NR 6E-7 6.222 rs10799713 5.007 testosterone measurement (EFO:0004908)
 PMID:35192695
GWAS919092_H GCST90104276 Testosterone levels in postmenopausal women 84,003 European ancestry individuals G 0.219647 0.000001 6 rs10799713 0.0287152 testosterone measurement (EFO:0004908)
 PMID:35192695
Database Acc Id Source(s)
GWAS Catalog GCST90104272 GWAS Catalog
  GCST90104296 GWAS Catalog

RGD Curation Notes
Note Type Note Reference