GWAS859666_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS859666_H (chronic obstructive pulmonary disease QTL GWAS859666 (human)) Homo sapiens

Symbol: GWAS859666_H
Name: chronic obstructive pulmonary disease QTL GWAS859666 (human)
RGD ID: 407210690
Trait: chronic obstructive pulmonary disease
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381549,351,432 - 49,351,433RGD_MAPPER_PIPELINEGRCh38
GRCh371549,643,629 - 49,643,630RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318611GALK2galactokinase 2154915577449367740Human
1605268FAM227Bfamily with sequence similarity 227 member B154932697049620818Human

Position Markers

Peak: (rs12232354)
Human AssemblyChrPosition (strand)Source
GRCh381549,351,432 - 49,351,433RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407210690GWAS859666_Hchronic obstructive pulmonary disease QTL GWAS859666 (human)1e-08chronic obstructive pulmonary disease154935143249351433Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS859666_H GCST90399695 Chronic obstructive pulmonary disease 1,503 Admixed American ancestry cases, 13,583 Admixed American ancestry controls, 484 South Asian ancestry cases, 21,464 South Asian ancestry controls, 1,978 African ancestry cases, 27,704 African ancestry controls, 19,044 East Asian ancestry cases, 310,689 East Asian ancestry controls, 58,559 European ancestry cases, 937,358 European ancestry controls T 0.07365 1E-8 8 rs12232354 0.065336 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:36777996
Database Acc Id Source(s)
GWAS Catalog GCST90399695 GWAS Catalog

RGD Curation Notes
Note Type Note Reference