GWAS856750_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS856750_H (brain measurement QTL GWAS856750 (human)) Homo sapiens

Symbol: GWAS856750_H
Name: brain measurement QTL GWAS856750 (human)
RGD ID: 407207774
Trait: brain measurement
Measurement Type: brain measurement   (CMO:0000911)    
LOD Score: Not Available
P Value: 4.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38119,647,426 - 19,647,427RGD_MAPPER_PIPELINEGRCh38
GRCh37119,973,920 - 19,973,921RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS856750_HHumanbrain measurement  IAGPrs2854108405850206Based on the EFO term IDGWAS_CATALOGPMID:35505052

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS856750_HHumanbrain measurement  IAGPrs2854108405850206 GWAS_CATALOGPMID:35505052
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7243405MICOS10-NBL1MICOS10-NBL1 readthrough11959697919658452Human
736912NBL1NBL1, DAN family BMP antagonist11964322919658452Human

Position Markers

Peak: (rs2854108)
Human AssemblyChrPosition (strand)Source
GRCh38119,647,426 - 19,647,427RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407207774GWAS856750_Hbrain measurement QTL GWAS856750 (human)4e-16brain measurementbrain measurement (CMO:0000911)11964742619647427Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407207720GWAS856696_Hbrain measurement QTL GWAS856696 (human)6e-11brain measurementbrain measurement (CMO:0000911)11964742619647427Human
407174570GWAS823546_Hcortical surface area measurement, neuroimaging measurement QTL GWAS823546 (human)3e-14cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)11964742619647427Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS823546_H GCST010701 Cortical surface area (MOSTest) 26,502 European ancestry individuals ? NR 3E-14 13.523 rs2854108 N/A cortical surface area measurement (EFO:0010736)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS856696_H GCST90131906 Whole brain free water diffusion (multivariate analysis) 23,543 European ancestry individuals ? NR 6E-11 10.222 rs2854108 N/A brain measurement (EFO:0004464)
 PMID:35505052
GWAS856750_H GCST90131905 Whole brain restricted directional diffusion (multivariate analysis) 23,543 European ancestry individuals ? NR 4E-16 15.398 rs2854108 N/A brain measurement (EFO:0004464)
 PMID:35505052
Database Acc Id Source(s)
GWAS Catalog GCST90131905 GWAS Catalog

RGD Curation Notes
Note Type Note Reference