GWAS846148_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS846148_H (breast cancer, lung cancer QTL GWAS846148 (human)) Homo sapiens

Symbol: GWAS846148_H
Name: breast cancer, lung cancer QTL GWAS846148 (human)
RGD ID: 407197172
Trait: breast cancer, lung cancer
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38629,931,900 - 29,931,901RGD_MAPPER_PIPELINEGRCh38
GRCh37629,899,677 - 29,899,678RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS846148_HHumanbreast cancer  IAGPrs2524005405850206 GWAS_CATALOGPMID:36819030
GWAS846148_HHumanlung cancer  IAGPrs2524005405850206 GWAS_CATALOGPMID:36819030
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
151673698LOC124901298uncharacterized LOC12490129862992819829945593Human

Position Markers

Peak: (rs2524005)
Human AssemblyChrPosition (strand)Source
GRCh38629,931,900 - 29,931,901RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407013971GWAS662947_Hbipolar disorder, schizophrenia QTL GWAS662947 (human)0.0000005bipolar disorder, schizophrenia62993190029931901Human
407197172GWAS846148_Hbreast cancer, lung cancer QTL GWAS846148 (human)4e-08breast cancer, lung cancer62993190029931901Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
407252137GWAS901113_HVaricose veins QTL GWAS901113 (human)1e-12Varicose veins62993190029931901Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS662947_H GCST001567 Bipolar disorder and schizophrenia 2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls ? NR 5E-7 6.302 rs2524005 1.32 PMID:22688191
GWAS846148_H GCST90270343 Breast cancer or lung cancer (pleiotropy) 122,977 breast cancer cases, 11,348 lung cancer cases, 121,835 controls G NR 4E-8 7.398 rs2524005 N/A PMID:36819030
GWAS901113_H GCST90018939 Varicose veins 22,037 European ancestry cases, 437,665 European ancestry controls, 474 East Asian ancestry cases, 178,252 East Asian ancestry controls A NR 1E-12 12 rs2524005 0.0995 Varicose veins (HP:0002619)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90270343 GWAS Catalog

RGD Curation Notes
Note Type Note Reference