GWAS843626_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS843626_H (free cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS843626 (human)) Homo sapiens

Symbol: GWAS843626_H
Name: free cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS843626 (human)
RGD ID: 407194650
Trait: blood lipid amount   (VT:0003949)    
Measurement Type: blood cholesterol level   (CMO:0002280)    
blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
blood low density lipoprotein cholesterol level   (CMO:0000053)    
blood total cholesterol level   (CMO:0000051)    
blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38318,222,564 - 18,222,565RGD_MAPPER_PIPELINEGRCh38
GRCh37318,264,056 - 18,264,057RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS843626_HHumanblood lipid amount  IAGPrs187814248405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38630732BALR6B-cell acute lymphoblastic leukemia associated long RNA 631796255218268922Human

Position Markers

Peak: (rs187814248)
Human AssemblyChrPosition (strand)Source
GRCh38318,222,564 - 18,222,565RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407244374GWAS893350_Hfree cholesterol measurement, intermediate density lipoprotein measurement QTL GWAS893350 (human)2e-08blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)31822256418222565Human
407237152GWAS886128_Hphospholipid measurement, intermediate density lipoprotein measurement QTL GWAS886128 (human)1e-08phospholipid measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)31822256418222565Human
407242737GWAS891713_Hlipid measurement, intermediate density lipoprotein measurement QTL GWAS891713 (human)3e-08lipid measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)31822256418222565Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
407194650GWAS843626_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS843626 (human)4e-08blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)31822256418222565Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS843626_H GCST90092860 Free cholesterol levels in large LDL 115,082 European ancestry individuals T 0.994129 4E-8 7.398 rs187814248 0.156634 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS886128_H GCST90092839 Phospholipid levels in IDL 115,082 European ancestry individuals T 0.994129 1E-8 8 rs187814248 0.160438 phospholipid measurement (EFO:0004639)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS891713_H GCST90092837 Total lipid levels in IDL 115,082 European ancestry individuals T 0.994129 3E-8 7.523 rs187814248 0.156298 lipid measurement (EFO:0004529)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS893350_H GCST90092835 Free cholesterol levels in IDL 115,082 European ancestry individuals T 0.994129 2E-8 7.699 rs187814248 0.158574 free cholesterol measurement (EFO:0008591)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90092918 Cholesteryl ester levels in medium VLDL 115,082 European ancestry individuals T 0.994129 2E-8 7.699 rs187814248 0.163122 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90092831 Cholesterol levels in IDL 115,082 European ancestry individuals T 0.994129 4E-8 7.398 rs187814248 0.154255 total cholesterol measurement (EFO:0004574)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
None Available GCST90093030 Cholesteryl ester levels in very small VLDL 115,082 European ancestry individuals T 0.994129 4E-8 7.398 rs187814248 0.154215 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092831 GWAS Catalog
  GCST90092860 GWAS Catalog
  GCST90093030 GWAS Catalog

RGD Curation Notes
Note Type Note Reference