GWAS835825_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS835825_H (phosphatidylcholine measurement QTL GWAS835825 (human)) Homo sapiens

Symbol: GWAS835825_H
Name: phosphatidylcholine measurement QTL GWAS835825 (human)
RGD ID: 407186849
Trait: phosphatidylcholine measurement
LOD Score: Not Available
P Value: 4.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,452,282 - 58,452,283RGD_MAPPER_PIPELINEGRCh38
GRCh371558,744,481 - 58,744,482RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS835825_HHumanphosphatidylcholine measurement  IAGPrs35138338405850206 GWAS_CATALOGPMID:34503513
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736877LIPClipase C, hepatic type155843199158569844Human
11084824LIPC-AS1LIPC antisense RNA 1155843490158498735Human

Position Markers

Peak: (rs35138338)
Human AssemblyChrPosition (strand)Source
GRCh381558,452,282 - 58,452,283RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407196869GWAS845845_Hphosphatidylethanolamine measurement QTL GWAS845845 (human)0.0000006blood lipid amount (VT:0003949)155845228258452283Human
407149894GWAS798870_Htotal cholesterol measurement QTL GWAS798870 (human)3e-13total cholesterol measurementblood total cholesterol level (CMO:0000051)155845228258452283Human
407190150GWAS839126_Hphosphatidylethanolamine measurement QTL GWAS839126 (human)2e-13phosphatidylethanolamine measurement155845228258452283Human
407198918GWAS847894_Hphosphatidylethanolamine measurement QTL GWAS847894 (human)4e-08phosphatidylethanolamine measurement155845228258452283Human
407199622GWAS848598_Hlysophosphatidylethanolamine 18:0 measurement QTL GWAS848598 (human)2e-08blood lipid amount (VT:0003949)155845228258452283Human
407186849GWAS835825_Hphosphatidylcholine measurement QTL GWAS835825 (human)4e-10phosphatidylcholine measurement155845228258452283Human
407157538GWAS806514_Htriglyceride measurement QTL GWAS806514 (human)3e-10triglyceride measurementblood triglyceride level (CMO:0000118)155845228258452283Human
407154956GWAS803932_Hhigh density lipoprotein cholesterol measurement QTL GWAS803932 (human)5e-33high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155845228258452283Human
407221453GWAS870429_Hlow density lipoprotein cholesterol measurement QTL GWAS870429 (human)2e-31low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155845228258452283Human
407152622GWAS801598_Hapolipoprotein A 1 measurement QTL GWAS801598 (human)5e-46apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)155845228258452283Human
407196175GWAS845151_Hphosphatidylethanolamine measurement QTL GWAS845151 (human)7e-08phosphatidylethanolamine measurement155845228258452283Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407191735GWAS840711_Hphosphatidylethanolamine measurement QTL GWAS840711 (human)1e-12phosphatidylethanolamine measurement155845228258452283Human
407188177GWAS837153_Hphosphatidylcholine measurement QTL GWAS837153 (human)2e-10phosphatidylcholine measurement155845228258452283Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407227600GWAS876576_Hhigh density lipoprotein cholesterol measurement QTL GWAS876576 (human)6e-13high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155845228258452283Human
407199634GWAS848610_Hlysophosphatidylethanolamine 16:0 measurement QTL GWAS848610 (human)0.0000001blood lipid amount (VT:0003949)155845228258452283Human
407198682GWAS847658_Hphosphatidylethanolamine measurement QTL GWAS847658 (human)0.000001phosphatidylethanolamine measurement155845228258452283Human
407186394GWAS835370_Hphosphatidylcholine measurement QTL GWAS835370 (human)1e-11phosphatidylcholine measurement155845228258452283Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS798870_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals T NR 3E-13 12.523 rs35138338 0.0195 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS801598_H GCST90019495 Apolipoprotein A1 levels 311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals T NR 5E-46 45.302 rs35138338 0.04 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:33462484
GWAS803932_H GCST90019510 High density lipoprotein cholesterol levels 313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals T NR 5E-33 32.302 rs35138338 0.0335 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:33462484
GWAS806514_H GCST90019523 Triglyceride levels 342,233 European ancestry individuals, 6,014 African ancestry individuals, 7,330 South Asian ancestry individuals T NR 3E-10 9.523 rs35138338 0.0169 triglyceride measurement (EFO:0004530)
 PMID:33462484
GWAS835370_H GCST90060316 Phosphatidylcholine_35:4_[M+H]1+/Phosphatidylethanolamine_38:4_[M+H]1+/Phosphatidate_40:5_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 1E-11 11 rs35138338 0.0863069 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS835825_H GCST90060273 Phosphatidylcholine_33:4_[M+H]1+/Phosphatidylethanolamine_36:4_[M+H]1+/Phosphatidate_38:5_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 4E-10 9.398 rs35138338 0.0815678 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS837153_H GCST90060249 Phosphatidylcholine_31:2_[M+H]1+/Phosphatidylethanolamine_34:2_[M+H]1+/Phosphatidate_36:3_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 2E-10 9.699 rs35138338 0.0846218 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS839126_H GCST90060272 Phosphatidylethanolamine_36:4_[M-H]1- levels 13,814 British ancestry individuals T NR 2E-13 12.699 rs35138338 0.0931831 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS840711_H GCST90060310 Phosphatidylethanolamine_38:6_[M-H]1- levels 13,814 British ancestry individuals T NR 1E-12 12 rs35138338 0.0913217 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS845151_H GCST90024597 Total Phosphatidylethanolamine levels 4,492 European ancestry individuals T NR 7E-8 7.155 rs35138338 0.15 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS845845_H GCST90024356 Phosphatidylethanolamine (16:0_20:4) levels 4,492 European ancestry individuals T NR 6E-7 6.222 rs35138338 0.138 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS847658_H GCST90024379 Phosphatidylethanolamine (38:5) (a) levels 4,492 European ancestry individuals T NR 0.000001 6 rs35138338 0.136 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS847894_H GCST90024369 Phosphatidylethanolamine (18:0_20:4) levels 4,492 European ancestry individuals T NR 4E-8 7.398 rs35138338 0.152 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS848598_H GCST90024208 Lysophosphatidylethanolamine (18:0) [sn1] levels 4,492 European ancestry individuals T NR 2E-8 7.699 rs35138338 0.156 lysophosphatidylethanolamine 18:0 measurement (EFO:0010367)
 PMID:35668104
GWAS848610_H GCST90024205 Lysophosphatidylethanolamine (16:0) [sn2] levels 4,492 European ancestry individuals T NR 1E-7 7 rs35138338 0.147 lysophosphatidylethanolamine 16:0 measurement (EFO:0010366)
 PMID:35668104
None Available GCST90024204 Lysophosphatidylethanolamine (16:0) [sn1] levels 4,492 European ancestry individuals T NR 6E-7 6.222 rs35138338 0.139 lysophosphatidylethanolamine 16:0 measurement (EFO:0010366)
 PMID:35668104
GWAS870429_H GCST90179148 Low-density lipoprotein levels (MTAG) 361,194 European ancestry individuals T NR 2E-31 30.699 rs35138338 0.01814 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36376304
GWAS876576_H GCST90179147 High-density lipoprotein levels (MTAG) 361,194 European ancestry individuals T NR 6E-13 12.222 rs35138338 0.02118 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36376304
Database Acc Id Source(s)
GWAS Catalog GCST90060273 GWAS Catalog

RGD Curation Notes
Note Type Note Reference