GWAS834833_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS834833_H (free cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS834833 (human)) Homo sapiens

Symbol: GWAS834833_H
Name: free cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS834833 (human)
RGD ID: 407185857
Trait: free cholesterol measurement, low density lipoprotein cholesterol measurement
Measurement Type: blood cholesterol level   (CMO:0002280)    
blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,069,142 - 160,069,143RGD_MAPPER_PIPELINEGRCh38
GRCh376160,490,174 - 160,490,175RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS834833_HHumanblood cholesterol level  IAGPrs2065397405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS834833_HHumanblood low density lipoprotein cholesterol level  IAGPrs2065397405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS834833_HHumanfree cholesterol measurement  IAGPrs2065397405850206 GWAS_CATALOGPMID:35213538
GWAS834833_HHumanlow density lipoprotein cholesterol measurement  IAGPrs2065397405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732660IGF2Rinsulin like growth factor 2 receptor6159969082160111504Human
151676529LOC124901451uncharacterized LOC1249014516160068902160069545Human

Position Markers

Peak: (rs2065397)
Human AssemblyChrPosition (strand)Source
GRCh386160,069,142 - 160,069,143RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407185857GWAS834833_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS834833 (human)3e-09free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6160069142160069143Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS834833_H GCST90092860 Free cholesterol levels in large LDL 115,082 European ancestry individuals G 0.630077 3E-9 8.523 rs2065397 0.0248675 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092860 GWAS Catalog

RGD Curation Notes
Note Type Note Reference