GWAS817611_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS817611_H (diacylglycerol 34:2 measurement QTL GWAS817611 (human)) Homo sapiens

Symbol: GWAS817611_H
Name: diacylglycerol 34:2 measurement QTL GWAS817611 (human)
RGD ID: 407168635
Trait: milk diacylglycerol amount   (VT:0010385)    
LOD Score: Not Available
P Value: 1.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3811116,832,924 - 116,832,925RGD_MAPPER_PIPELINEGRCh38
GRCh3711116,703,640 - 116,703,641RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS817611_HHumanmilk diacylglycerol amount  IAGPrs5128405850206Based on the EFO term IDGWAS_CATALOGPMID:34503513

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS817611_HHumandiacylglycerol 34:2 measurement  IAGPrs5128405850206 GWAS_CATALOGPMID:34503513
Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
737569APOC3apolipoprotein C311116829907116833072Human

Position Markers

Peak: (rs5128)
Human AssemblyChrPosition (strand)Source
GRCh3811116,832,924 - 116,832,925RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407118980GWAS767956_Hsexual dimorphism measurement QTL GWAS767956 (human)6e-33sexual dimorphism measurement11116832924116832925Human
407205228GWAS854204_Hphosphatidylcholine measurement QTL GWAS854204 (human)4e-11phosphatidylcholine measurement11116832924116832925Human
407172462GWAS821438_Hsterol measurement QTL GWAS821438 (human)2e-14sphingomyelin measurementblood sterol level (CMO:0002048)11116832924116832925Human
407239694GWAS888670_Hsphingomyelin measurement QTL GWAS888670 (human)5e-12sphingomyelin measurement11116832924116832925Human
407237608GWAS886584_Hsphingomyelin measurement QTL GWAS886584 (human)3e-14sphingomyelin measurement11116832924116832925Human
407269495GWAS918471_Hsphingomyelin measurement QTL GWAS918471 (human)2e-17sphingomyelin measurement11116832924116832925Human
407170838GWAS819814_Hdiacylglycerol 44:7 measurement QTL GWAS819814 (human)5e-14diacylglycerol 44:7 measurement11116832924116832925Human
407165783GWAS814759_Hdiacylglycerol 36:2 measurement QTL GWAS814759 (human)2e-11milk diacylglycerol amount (VT:0010385)11116832924116832925Human
407167536GWAS816512_Htriglyceride measurement QTL GWAS816512 (human)2e-10triglyceride measurementblood triglyceride level (CMO:0000118)11116832924116832925Human
407207088GWAS856064_Hphosphatidylcholine measurement QTL GWAS856064 (human)7e-11sphingomyelin measurement11116832924116832925Human
407197970GWAS846946_Htriglyceride measurement QTL GWAS846946 (human)3e-11triglyceride measurementblood triglyceride level (CMO:0000118)11116832924116832925Human
407175196GWAS824172_Hcholesteryl ester 18:3 measurement QTL GWAS824172 (human)3e-10blood lipid amount (VT:0003949)11116832924116832925Human
406891418GWAS540394_Hbeta-endorphin measurement QTL GWAS540394 (human)5e-44beta-endorphin measurement11116832924116832925Human
1559115SCL20_HSerum cholesterol level QTL 20 (human)3.220.001213Lipid levelLDL cholesterol11100442501126442501Human
407164632GWAS813608_Htriglyceride measurement QTL GWAS813608 (human)4e-10triglyceride measurementblood triglyceride level (CMO:0000118)11116832924116832925Human
407266840GWAS915816_Hsphingomyelin measurement QTL GWAS915816 (human)9e-13sphingomyelin measurement11116832924116832925Human
407168635GWAS817611_Hdiacylglycerol 34:2 measurement QTL GWAS817611 (human)1e-11milk diacylglycerol amount (VT:0010385)11116832924116832925Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS540394_H GCST90240434 Beta-endorphin levels (POMC.2558.51.3) 3,301 European ancestry individuals C 0.916 5E-44 43.302 rs5128 0.6 beta-endorphin measurement (EFO:0008034)
 PMID:29875488
GWAS767956_H GCST90270118 Multi-trait sex score 141,980 European ancestry males ? NR 6E-33 32.222 rs5128 N/A sexual dimorphism measurement (EFO:0021796)
 PMID:37277458
GWAS813608_H GCST90060511 Triacylglycerol_52:2_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 4E-10 9.398 rs5128 0.161754 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS814759_H GCST90060191 Diacylglycerol_36:2_[M+H-H2O]1+ levels 13,814 British ancestry individuals G NR 2E-11 10.699 rs5128 0.124889 diacylglycerol 36:2 measurement (EFO:0010355)
 PMID:34503513
GWAS816512_H GCST90060509 Triacylglycerol_52:3_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 2E-10 9.699 rs5128 0.164684 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS817611_H GCST90060178 Diacylglycerol_34:2_[M+H-H2O]1+ levels 13,814 British ancestry individuals G NR 1E-11 11 rs5128 0.125272 diacylglycerol 34:2 measurement (EFO:0010353)
 PMID:34503513
GWAS819814_H GCST90060240 Diacylglycerol_44:7_[M+H-H2O]1+ levels 13,814 British ancestry individuals G NR 5E-14 13.302 rs5128 0.154266 diacylglycerol 44:7 measurement (EFO:0020069)
 PMID:34503513
None Available GCST90060179 Diacylglycerol_34:1_[M+H-H2O]1+ levels 13,814 British ancestry individuals G NR 2E-11 10.699 rs5128 0.127303 diacylglycerol 34:1 measurement (EFO:0010352)
 PMID:34503513
GWAS821438_H GCST90060133 Cholesterol_[M+H-H2O]1+ levels 13,814 British ancestry individuals G NR 2E-14 13.699 rs5128 0.11917 sterol measurement (EFO:0010231)
 PMID:34503513
GWAS824172_H GCST90060218 Cholesteryl ester_18:3_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 3E-10 9.523 rs5128 0.114476 cholesteryl ester 18:3 measurement (EFO:0010346)
 PMID:34503513
None Available GCST90060333 Triacylglycerol_45:4_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 2E-10 9.699 rs5128 0.131882 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS846946_H GCST90060362 Triacylglycerol_46:4_[M+NH4]1+ levels 13,814 British ancestry individuals G NR 3E-11 10.523 rs5128 0.171523 triglyceride measurement (EFO:0004530)
 PMID:34503513
GWAS854204_H GCST90060277 Phosphatidylcholine-O_34:3_[M+H]1+/Phosphatidylcholine-P_34:2_[M+H]1+/Phosphatidylethanolamine-P_37:2_[M+H]1+ levels 13,814 British ancestry individuals G NR 4E-11 10.398 rs5128 0.140425 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS856064_H GCST90060243 Phosphatidylcholine-O_31:0_[M+H]1+/Phosphatidylethanolamine-O_34:0_[M+H]1+ levels 13,814 British ancestry individuals G NR 7E-11 10.155 rs5128 0.133485 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS886584_H GCST90060241 Sphingomyelin_34:0_[M+H]1+ levels 13,814 British ancestry individuals G NR 3E-14 13.523 rs5128 0.155673 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS888670_H GCST90060269 Sphingomyelin_36:0_[M+H]1+ levels 13,814 British ancestry individuals G NR 5E-12 11.302 rs5128 0.140211 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS915816_H GCST90060266 Sphingomyelin_36:1_[M+H]1+ levels 13,814 British ancestry individuals G NR 9E-13 12.046 rs5128 0.149093 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90060328 Sphingomyelin_39:1_[M+H]1+ levels 13,814 British ancestry individuals G NR 2E-11 10.699 rs5128 0.139934 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90060239 Sphingomyelin_34:1_[M+H]1+ levels 13,814 British ancestry individuals G NR 2E-14 13.699 rs5128 0.1627 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90060403 Sphingomyelin_42:2_[M+H]1+ levels 13,814 British ancestry individuals G NR 3E-10 9.523 rs5128 0.158509 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90060364 Sphingomyelin_40:0_[M+H]1+ levels 13,814 British ancestry individuals G NR 2E-11 10.699 rs5128 0.171238 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90060358 Sphingomyelin_40:1_[M+H]1+ levels 13,814 British ancestry individuals G NR 7E-11 10.155 rs5128 0.170165 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS918471_H GCST90060306 Sphingomyelin_38:1_[M+H]1+ levels 13,814 British ancestry individuals G NR 2E-17 16.699 rs5128 0.175826 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
None Available GCST90454454 Metabolic syndrome 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls C 0.3061 1E-13 13 rs5128 0.08526 metabolic syndrome (EFO:0000195)
 PMID:38201907
Database Acc Id Source(s)
GWAS Catalog GCST90060178 GWAS Catalog

RGD Curation Notes
Note Type Note Reference