GWAS806213_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS806213_H (type 2 diabetes mellitus QTL GWAS806213 (human)) Homo sapiens

Symbol: GWAS806213_H
Name: type 2 diabetes mellitus QTL GWAS806213 (human)
RGD ID: 407157237
Trait: type 2 diabetes mellitus
LOD Score: Not Available
P Value: 2.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381265,964,567 - 65,964,568RGD_MAPPER_PIPELINEGRCh38
GRCh371266,358,347 - 66,358,348RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS806213_HHumantype 2 diabetes mellitus  IAGPrs1042725405850206 GWAS_CATALOGPMID:30297969
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348013HMGA2high mobility group AT-hook 2126582446065966291Human

Position Markers

Peak: (rs1042725)
Human AssemblyChrPosition (strand)Source
GRCh381265,964,567 - 65,964,568RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407008164GWAS657140_Hsex hormone-binding globulin measurement QTL GWAS657140 (human)4e-19sex hormone-binding globulin measurement126596456765964568Human
407049765GWAS698741_Hbody height QTL GWAS698741 (human)0.0000002body height (VT:0001253)body height (CMO:0000106)126596456765964568Human
406923208GWAS572184_Hbirth weight QTL GWAS572184 (human)2e-33birth weightneonatal body weight (CMO:0002079)126596456765964568Human
407008363GWAS657339_Hsex hormone-binding globulin measurement QTL GWAS657339 (human)8e-25sex hormone-binding globulin measurement126596456765964568Human
407347564GWAS996540_Hsystolic blood pressure QTL GWAS996540 (human)2e-10systolic blood pressuresystolic blood pressure (CMO:0000004)126596456765964568Human
407020334GWAS669310_Hbody height QTL GWAS669310 (human)3e-18body height (VT:0001253)body height (CMO:0000106)126596456765964568Human
406931085GWAS580061_Hbody height at birth QTL GWAS580061 (human)2e-29body height at birthbody height (CMO:0000106)126596456765964568Human
407100205GWAS749181_Hleukocyte count QTL GWAS749181 (human)3e-16leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)126596456765964568Human
407005074GWAS654050_Hneutrophil count QTL GWAS654050 (human)3e-11neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)126596456765964568Human
407157237GWAS806213_Htype 2 diabetes mellitus QTL GWAS806213 (human)2e-13type 2 diabetes mellitus126596456765964568Human
407249044GWAS898020_Hcorneal resistance factor QTL GWAS898020 (human)7e-09corneal resistance factor126596456765964568Human
406989424GWAS638400_Hbody height QTL GWAS638400 (human)3e-10body height (VT:0001253)body height (CMO:0000106)126596456765964568Human
406931092GWAS580068_Hinfant head circumference QTL GWAS580068 (human)9e-22infant head circumference126596456765964568Human
407020180GWAS669156_Hbody height QTL GWAS669156 (human)3e-20body height (VT:0001253)body height (CMO:0000106)126596456765964568Human
407039349GWAS688325_Hbirth weight QTL GWAS688325 (human)1e-19birth weightneonatal body weight (CMO:0002079)126596456765964568Human
407022780GWAS671756_Hbody height QTL GWAS671756 (human)6e-16body height (VT:0001253)body height (CMO:0000106)126596456765964568Human
406925086GWAS574062_Happendicular lean mass QTL GWAS574062 (human)1e-14appendicular lean mass126596456765964568Human
406986141GWAS635117_Hbrain volume measurement QTL GWAS635117 (human)7e-11brain volume measurementbrain morphological measurement (CMO:0000136)126596456765964568Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS572184_H GCST009498 Birth weight (MTAG) up to 182,902 European ancestry individuals T 0.49 2E-33 32.699 rs1042725 0.044908717 birth weight (EFO:0004344)
 PMID:31681408
GWAS574062_H GCST009577 Appendicular lean mass 181,862 European ancestry elderly individuals T 0.493581 1E-14 14 rs1042725 0.0526547 appendicular lean mass (EFO:0004980)
 PMID:31761296
GWAS580061_H GCST009499 Birth length (MTAG) up to 182,902 European ancestry individuals T 0.504 2E-29 28.699 rs1042725 0.06538093 body height at birth (EFO:0006784)
 PMID:31681408
GWAS580068_H GCST009500 Infant head circumference (MTAG) up to 182,902 European ancestry individuals T 0.4901 9E-22 21.046 rs1042725 0.10481363 infant head circumference (EFO:0004577)
 PMID:31681408
GWAS635117_H GCST011616 Cortical volume 22,824 European and African American ancestry individuals ? NR 7E-11 10.155 rs1042725 N/A brain volume measurement (EFO:0006930)
 PMID:32963231
GWAS638400_H GCST008053 Height 17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals ? NR 3E-10 9.523 rs1042725 0.03672127 body height (EFO:0004339)
 PMID:31217584
GWAS654050_H GCST90002351 Neutrophil count 519,288 European ancestry individuals T 0.494436 3E-11 10.523 rs1042725 0.012765 neutrophil count (EFO:0004833)
 PMID:32888493
GWAS657140_H GCST90012111 Sex hormone-binding globulin levels 370,125 European ancestry individuals C 0.508157 4E-19 18.398 rs1042725 0.00812764 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS657339_H GCST90012110 Sex hormone-binding globulin levels adjusted for BMI 368,929 European ancestry individuals C 0.508157 8E-25 24.097 rs1042725 0.0083042 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS669156_H GCST000176 Height 15,821 European ancestry individuals T 0.49 3E-20 19.523 rs1042725 0.48 body height (EFO:0004339)
 PMID:18391950
GWAS669310_H GCST000174 Height 13,665 European ancestry individuals C 0.49 3E-18 17.523 rs1042725 0.05 body height (EFO:0004339)
 PMID:18391952
GWAS671756_H GCST000068 Height 4,921 European ancestry individuals C 0.51 6E-16 15.222 rs1042725 0.4 body height (EFO:0004339)
 PMID:17767157
None Available GCST001484 Head circumference (infant) 10,768 European ancestry infants T 0.49 3E-10 9.523 rs1042725 0.065 infant head circumference (EFO:0004577)
 PMID:22504419
GWAS688325_H GCST001758 Birth weight Up to 26,836 European ancestry individuals T 0.50 1E-19 19 rs1042725 0.047 birth weight (EFO:0004344)
 PMID:23202124
GWAS698741_H GCST002702 Height 36,227 East Asian ancestry individuals T 0.73 2E-7 6.699 rs1042725 0.024 body height (EFO:0004339)
 PMID:25429064
GWAS749181_H GCST007070 White blood cell count approximately 444,000 European ancestry individuals ? NR 3E-16 15.523 rs1042725 N/A leukocyte count (EFO:0004308)
 PMID:30595370
GWAS806213_H GCST009379 Type 2 diabetes 74,124 European ancestry cases, 824,006 European ancestry controls T 0.4902 2E-13 12.699 rs1042725 1.05 PMID:30297969
GWAS898020_H GCST90100568 Corneal resistance factor 76,029 white-British ancestry individuals C 0.505629 7E-9 8.155 rs1042725 0.0530992 corneal resistance factor (EFO:0010067)
 PMID:33311554
GWAS996540_H GCST90132903 Systolic blood pressure 526,001 European ancestry individuals T NR 2E-10 9.699 rs1042725 0.2255 systolic blood pressure (EFO:0006335)
 PMID:35762941
Database Acc Id Source(s)
GWAS Catalog GCST009379 GWAS Catalog

RGD Curation Notes
Note Type Note Reference