GWAS797583_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS797583_H (lung adenocarcinoma QTL GWAS797583 (human)) Homo sapiens

Symbol: GWAS797583_H
Name: lung adenocarcinoma QTL GWAS797583 (human)
RGD ID: 407148607
Trait: lung adenocarcinoma
LOD Score: Not Available
P Value: 7.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381549,084,427 - 49,084,428RGD_MAPPER_PIPELINEGRCh38
GRCh371549,376,624 - 49,376,625RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs77468143)
Human AssemblyChrPosition (strand)Source
GRCh381549,084,427 - 49,084,428RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407280726GWAS929702_Hlung adenocarcinoma QTL GWAS929702 (human)2e-20lung adenocarcinoma154908442749084428Human
407152598GWAS801574_Hnon-small cell lung carcinoma QTL GWAS801574 (human)0.0000001non-small cell lung carcinoma154908442749084428Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407230929GWAS879905_Hlung adenocarcinoma QTL GWAS879905 (human)2e-16lung adenocarcinoma154908442749084428Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407232812GWAS881788_Hlung carcinoma QTL GWAS881788 (human)1e-09lung carcinoma154908442749084428Human
407148607GWAS797583_Hlung adenocarcinoma QTL GWAS797583 (human)7e-12lung adenocarcinoma154908442749084428Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
None Available GCST90455518 Lung cancer 39,664 European ancestry cases, 119,158 European ancestry controls, 2,438 African ancestry cases, 62,112 African ancestry controls T 0.76 9E-18 17.046 rs77468143 1.084 PMID:39366959
None Available GCST90455519 Lung adenocarcinoma (conditioned on cigarettes per day) 13,292 European ancestry cases, 67,596 European ancestry controls, 595 African ancestry cases, 62,112 African ancestry controls T 0.762 6E-29 28.222 rs77468143 1.17 lung adenocarcinoma (EFO:0000571)
 PMID:39366959
GWAS797583_H GCST012201 Lung adenocarcinoma 15,581 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls T NR 7E-12 11.155 rs77468143 1.14 lung adenocarcinoma (EFO:0000571)
 PMID:32889700
GWAS801574_H GCST012199 Non-small cell lung cancer 27,120 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls T NR 1E-7 7 rs77468143 1.09 non-small cell lung carcinoma (EFO:0003060)
 PMID:32889700
GWAS879905_H GCST004744 Lung adenocarcinoma 11,273 European ancestry cases, 55,483 European ancestry controls T 0.747375077 2E-16 15.699 rs77468143 1.1677256 lung adenocarcinoma (EFO:0000571)
 PMID:28604730
GWAS881788_H GCST004748 Lung cancer 29,266 European ancestry cases, 56,450 European ancestry controls T 0.7461243470000001 1E-9 9 rs77468143 1.0861762 lung carcinoma (EFO:0001071)
 PMID:28604730
None Available GCST008836 Lung adenocarcinoma 8,762 Chinese ancestry cases, 6,819 European ancestry cases, 13,328 Chinese ancestry controls, 14,027 European ancestry controls T 0.767 7E-12 11.155 rs77468143 1.14 lung adenocarcinoma (EFO:0000571)
 PMID:31326317
GWAS929702_H GCST90134662 Lung adenocarcinoma 9,791 European ancestry cases, 23,173 European ancestry controls, 4,630 East Asian ancestry cases, 5,372 East Asian ancestry controls, 844 African American cases, 3,774 African American controls ? NR 2E-20 19.699 rs77468143 0.13 lung adenocarcinoma (EFO:0000571)
 PMID:35915169
Database Acc Id Source(s)
GWAS Catalog GCST008836 GWAS Catalog
  GCST012201 GWAS Catalog

RGD Curation Notes
Note Type Note Reference