GWAS796970_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS796970_H (apolipoprotein B measurement QTL GWAS796970 (human)) Homo sapiens

Symbol: GWAS796970_H
Name: apolipoprotein B measurement QTL GWAS796970 (human)
RGD ID: 407147994
Trait: apolipoprotein B measurement
Measurement Type: blood apoliprotein B level   (CMO:0000522)    
LOD Score: Not Available
P Value: 6.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38312,585,017 - 12,585,018RGD_MAPPER_PIPELINEGRCh38
GRCh37312,626,516 - 12,626,517RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS796970_HHumanblood apoliprotein B level  IAGPrs3729931405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS796970_HHumanapolipoprotein B measurement  IAGPrs3729931405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
737596RAF1Raf-1 proto-oncogene, serine/threonine kinase31258360112664117Human

Position Markers

Peak: (rs3729931)
Human AssemblyChrPosition (strand)Source
GRCh38312,585,017 - 12,585,018RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406980195GWAS629171_Hcardiac hypertrophy QTL GWAS629171 (human)0.0000007cardiac hypertrophy31258501712585018Human
407153607GWAS802583_HHbA1c measurement QTL GWAS802583 (human)3e-20HbA1c measurementblood hemoglobin A1c level (CMO:0002786)31258501712585018Human
407199558GWAS848534_HBMI-adjusted hip circumference QTL GWAS848534 (human)2e-12BMI-adjusted hip circumferencehip circumference (CMO:0000014)31258501712585018Human
407152931GWAS801907_Hsex hormone-binding globulin measurement QTL GWAS801907 (human)3e-12low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)31258501712585018Human
407149084GWAS798060_Htotal cholesterol measurement QTL GWAS798060 (human)6e-15total cholesterol measurementblood total cholesterol level (CMO:0000051)31258501712585018Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
407147994GWAS796970_Hapolipoprotein B measurement QTL GWAS796970 (human)6e-12apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)31258501712585018Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS629171_H GCST000960 Cardiac hypertrophy 851 Old Order Amish individuals ? NR 7E-7 6.155 rs3729931 N/A cardiac hypertrophy (EFO:0002503)
 PMID:21348951
GWAS796970_H GCST90019496 Apolipoprotein B levels 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals A NR 6E-12 11.222 rs3729931 0.0171 apolipoprotein B measurement (EFO:0004615)
 PMID:33462484
GWAS798060_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals A NR 6E-15 14.222 rs3729931 0.0193 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS801907_H GCST90019518 Sex hormone-binding globulin levels 310,323 European ancestry individuals, 5,523 African ancestry individuals, 6,638 South Asian ancestry individuals A NR 3E-12 11.523 rs3729931 0.0182 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:33462484
GWAS802583_H GCST90019509 Glycated hemoglobin levels 327,177 European ancestry individuals, 4,847 African ancestry individuals, 6,895 South Asian ancestry individuals A NR 3E-20 19.523 rs3729931 0.0234 HbA1c measurement (EFO:0004541)
 PMID:33462484
None Available GCST90019512 Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals A NR 3E-12 11.523 rs3729931 0.0173 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:33462484
GWAS848534_H GCST90020026 Hip index 219,872 British ancestry women A NR 2E-12 11.699 rs3729931 0.0213226 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
Database Acc Id Source(s)
GWAS Catalog GCST90019496 GWAS Catalog

RGD Curation Notes
Note Type Note Reference