GWAS788595_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS788595_H (type 2 diabetes mellitus QTL GWAS788595 (human)) Homo sapiens

Symbol: GWAS788595_H
Name: type 2 diabetes mellitus QTL GWAS788595 (human)
RGD ID: 407139619
Trait: type 2 diabetes mellitus
LOD Score: Not Available
P Value: 5.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381589,831,025 - 89,831,026RGD_MAPPER_PIPELINEGRCh38
GRCh371590,374,257 - 90,374,258RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS788595_HHumantype 2 diabetes mellitus  IAGPrs2028299405850206 GWAS_CATALOGPMID:24509480
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1350010AP3S2adaptor related protein complex 3 subunit sigma 2158983059989893994Human
5013871ARPIN-AP3S2ARPIN-AP3S2 readthrough158983059989912952Human

Position Markers

Peak: (rs2028299)
Human AssemblyChrPosition (strand)Source
GRCh381589,831,025 - 89,831,026RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407145761GWAS794737_Htype 2 diabetes mellitus QTL GWAS794737 (human)0.000003type 2 diabetes mellitus158983102589831026Human
407139619GWAS788595_Htype 2 diabetes mellitus QTL GWAS788595 (human)0.0000005type 2 diabetes mellitus158983102589831026Human
407142655GWAS791631_Htype 2 diabetes mellitus QTL GWAS791631 (human)4e-08type 2 diabetes mellitus158983102589831026Human
407145272GWAS794248_Htype 2 diabetes mellitus QTL GWAS794248 (human)2e-11type 2 diabetes mellitus158983102589831026Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS788595_H GCST002352 Type 2 diabetes 12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ancestry controls C 0.29 5E-7 6.302 rs2028299 1.04 PMID:24509480
GWAS791631_H GCST004894 Type 2 diabetes 6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls A 0.7326 4E-8 7.398 rs2028299 0.062 PMID:28869590
GWAS794248_H GCST001213 Type 2 diabetes 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls C 0.31 2E-11 10.699 rs2028299 1.1 PMID:21874001
GWAS794737_H GCST002128 Type 2 diabetes 5,976 Japanese ancestry cases, 20,829 Japanese ancestry controls C 0.23 0.000003 5.523 rs2028299 1.13 PMID:23945395
Database Acc Id Source(s)
GWAS Catalog GCST002352 GWAS Catalog

RGD Curation Notes
Note Type Note Reference