GWAS785904_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS785904_H (corneal resistance factor QTL GWAS785904 (human)) Homo sapiens

Symbol: GWAS785904_H
Name: corneal resistance factor QTL GWAS785904 (human)
RGD ID: 407136928
Trait: corneal resistance factor
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,097,186 - 11,097,187RGD_MAPPER_PIPELINEGRCh38
GRCh37111,157,243 - 11,157,244RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS785904_HHumancorneal resistance factor  IAGPrs534975221405850206 GWAS_CATALOGPMID:33311554
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1349336EXOSC10exosome component 1011106661811099869Human

Position Markers

Peak: (rs534975221)
Human AssemblyChrPosition (strand)Source
GRCh38111,097,186 - 11,097,187RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407136928GWAS785904_Hcorneal resistance factor QTL GWAS785904 (human)3e-10corneal resistance factor11109718611097187Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407005262GWAS654238_Hintraocular pressure measurement QTL GWAS654238 (human)2e-21intraocular pressure measurement11109718611097187Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407247019GWAS895995_Hcorneal resistance factor QTL GWAS895995 (human)2e-13corneal resistance factor11109718611097187Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS654238_H GCST005580 Intraocular pressure 115,486 European ancestry individuals G 0.9922 2E-21 20.699 rs534975221 0.7542 intraocular pressure measurement (EFO:0004695)
 PMID:29617998
GWAS785904_H GCST90308682 Corneal resistance factor 72,301 European ancestry individuals ? NR 3E-10 9.523 rs534975221 N/A corneal resistance factor (EFO:0010067)
 PMID:33311554
GWAS895995_H GCST90100568 Corneal resistance factor 76,029 white-British ancestry individuals G 0.992689 2E-13 12.699 rs534975221 0.366665 corneal resistance factor (EFO:0010067)
 PMID:33311554
Database Acc Id Source(s)
GWAS Catalog GCST90308682 GWAS Catalog

RGD Curation Notes
Note Type Note Reference