GWAS785753_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS785753_H (monocyte count QTL GWAS785753 (human)) Homo sapiens

Symbol: GWAS785753_H
Name: monocyte count QTL GWAS785753 (human)
RGD ID: 407136777
Trait: monocyte quantity   (VT:0000223)    
Measurement Type: blood monocyte count   (CMO:0000032)    
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38123,316,344 - 23,316,345RGD_MAPPER_PIPELINEGRCh38
GRCh37123,642,837 - 23,642,838RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS785753_HHumanblood monocyte count  IAGPrs10917370405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS785753_HHumanmonocyte quantity  IAGPrs10917370405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS785753_HHumanmonocyte count  IAGPrs10917370405850206 GWAS_CATALOGPMID:32888493
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736504HNRNPRheterogeneous nuclear ribonucleoprotein R12330468823344284Human

Position Markers

Peak: (rs10917370)
Human AssemblyChrPosition (strand)Source
GRCh38123,316,344 - 23,316,345RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407052883GWAS701859_Hmonocyte percentage of leukocytes QTL GWAS701859 (human)4e-13monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)12331634423316345Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407136777GWAS785753_Hmonocyte count QTL GWAS785753 (human)3e-10monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)12331634423316345Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS701859_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals G 0.177499 4E-13 12.398 rs10917370 0.021228231 monocyte percentage of leukocytes (EFO:0007989)
 PMID:32888494
GWAS785753_H GCST90002344 Monocyte count 639,696 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals G 0.18567 3E-10 9.523 rs10917370 N/A monocyte count (EFO:0005091)
 PMID:32888493
Database Acc Id Source(s)
GWAS Catalog GCST90002344 GWAS Catalog

RGD Curation Notes
Note Type Note Reference