GWAS783076_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS783076_H (rheumatoid arthritis QTL GWAS783076 (human)) Homo sapiens

Symbol: GWAS783076_H
Name: rheumatoid arthritis QTL GWAS783076 (human)
RGD ID: 407134100
Trait: rheumatoid arthritis
LOD Score: Not Available
P Value: 5.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386167,127,354 - 167,127,355RGD_MAPPER_PIPELINEGRCh38
GRCh376167,540,842 - 167,540,843RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1318406CCR6C-C motif chemokine receptor 66167111795167139141Human

Position Markers

Peak: (rs1571878)
Human AssemblyChrPosition (strand)Source
GRCh386167,127,354 - 167,127,355RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407167684GWAS816660_Hrheumatoid arthritis QTL GWAS816660 (human)4e-40rheumatoid arthritis6167127354167127355Human
407302181GWAS951157_Hrheumatoid arthritis, hypothyroidism QTL GWAS951157 (human)2e-22rheumatoid arthritis, hypothyroidism6167127354167127355Human
407180640GWAS829616_Hrheumatoid arthritis QTL GWAS829616 (human)1e-20rheumatoid arthritis6167127354167127355Human
407144360GWAS793336_Hrheumatoid arthritis QTL GWAS793336 (human)2e-08rheumatoid arthritis6167127354167127355Human
407232936GWAS881912_Hrheumatoid arthritis QTL GWAS881912 (human)5e-17rheumatoid arthritis6167127354167127355Human
407363336GWAS1012312_HImmunosuppressant use measurement QTL GWAS1012312 (human)3e-15Immunosuppressant use measurement6167127354167127355Human
407134100GWAS783076_Hrheumatoid arthritis QTL GWAS783076 (human)5e-15rheumatoid arthritis6167127354167127355Human
407141782GWAS790758_Hrheumatoid arthritis QTL GWAS790758 (human)1e-12Immunosuppressant use measurement6167127354167127355Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407146067GWAS795043_Hrheumatoid arthritis QTL GWAS795043 (human)2e-18rheumatoid arthritis6167127354167127355Human
407177212GWAS826188_Hrheumatoid arthritis QTL GWAS826188 (human)1e-31rheumatoid arthritis6167127354167127355Human
407145593GWAS794569_Hrheumatoid arthritis QTL GWAS794569 (human)5e-35rheumatoid arthritis6167127354167127355Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human
407145594GWAS794570_Hrheumatoid arthritis QTL GWAS794570 (human)1e-22rheumatoid arthritis6167127354167127355Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS783076_H GCST006959 Rheumatoid arthritis 916 African American cases, 1,392 African American controls, T 0.56 5E-15 14.302 rs1571878 0.12182 rheumatoid arthritis (EFO:0000685)
 PMID:30423114
GWAS790758_H GCST005568 Rheumatoid arthritis (ACPA-positive) up to 9,585 European ancestry cases, up to 33,742 European ancestry controls ? NR 1E-12 12 rs1571878 N/A rheumatoid arthritis (EFO:0000685)
 PMID:23143596
GWAS793336_H GCST005569 Rheumatoid arthritis up to 13,838 European ancestry cases, up to 33,742 European ancestry controls ? NR 2E-8 7.699 rs1571878 N/A rheumatoid arthritis (EFO:0000685)
 PMID:23143596
GWAS794569_H GCST002318 Rheumatoid arthritis up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls C 0.45 5E-35 34.302 rs1571878 1.17 rheumatoid arthritis (EFO:0000685)
 PMID:24390342
GWAS794570_H GCST002318 Rheumatoid arthritis up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls C 0.48 1E-22 22 rs1571878 1.28 rheumatoid arthritis (EFO:0000685)
 PMID:24390342
GWAS795043_H GCST002318 Rheumatoid arthritis up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls C 0.44 2E-18 17.699 rs1571878 1.13 rheumatoid arthritis (EFO:0000685)
 PMID:24390342
GWAS816660_H GCST90013534 Rheumatoid arthritis 14,361 European ancestry cases, 43,923 European ancestry controls, 8,267 East Asian ancestry cases, 244,741 East Asian ancestry controls T NR 4E-40 39.398 rs1571878 0.86 rheumatoid arthritis (EFO:0000685)
 PMID:33310728
GWAS826188_H GCST006959 Rheumatoid arthritis 916 African American cases, 1,392 African American controls, T NR 1E-31 31 rs1571878 0.145533 rheumatoid arthritis (EFO:0000685)
 PMID:30423114
GWAS829616_H GCST006959 Rheumatoid arthritis 916 African American cases, 1,392 African American controls, T 0.52 1E-20 20 rs1571878 0.24901 rheumatoid arthritis (EFO:0000685)
 PMID:30423114
None Available GCST90018771 Medication use (immunosuppressants) 3,483 East Asian ancestry cases, 175,243 East Asian ancestry controls T 0.511410148 1E-12 12 rs1571878 0.17926829 Immunosuppressant use measurement (EFO:0009934)
 PMID:34594039
GWAS881912_H GCST006048 Rheumatoid arthritis (ACPA-positive) 2,234 Korean ancestry cases, 7,065 Korean ancestry controls, 10,288 European ancestry cases, 35,502 European ancestry controls G 0.45 5E-17 16.302 rs1571878 1.14 rheumatoid arthritis (EFO:0000685)
 PMID:24532676
GWAS951157_H GCST90428109 Hypothyroidism or rheumatoid arthritis (pleiotropy) 22,350 European ancestry rheumatoid arthritis cases, 51,194 European ancestry hypothyroidism cases, 518,206 European ancestry controls ? NR 2E-22 21.699 rs1571878 N/A rheumatoid arthritis (EFO:0000685)
hypothyroidism (EFO:0004705)
 PMID:38368726
GWAS1012312_H GCST90018991 Medication use (immunosuppressants) 3,954 European ancestry cases, 268,648 European ancestry controls, 3,483 East Asian ancestry cases, 175,243 East Asian ancestry controls T NR 3E-15 14.523 rs1571878 0.1335 Immunosuppressant use measurement (EFO:0009934)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST006959 GWAS Catalog

RGD Curation Notes
Note Type Note Reference