GWAS782150_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS782150_H (esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS782150 (human)) Homo sapiens

Symbol: GWAS782150_H
Name: esterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS782150 (human)
RGD ID: 407133174
Trait: esterified cholesterol measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 2.0E-14
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381911,235,479 - 11,235,480RGD_MAPPER_PIPELINEGRCh38
GRCh371911,346,155 - 11,346,156RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS782150_HHumanblood high density lipoprotein cholesterol level  IAGPrs56322906405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS782150_HHumanesterified cholesterol measurement  IAGPrs56322906405850206 GWAS_CATALOGPMID:38448586
GWAS782150_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs56322906405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1315180DOCK6dedicator of cytokinesis 6191119929511262524Human

Position Markers

Peak: (rs56322906)
Human AssemblyChrPosition (strand)Source
GRCh381911,235,479 - 11,235,480RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407279748GWAS928724_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS928724 (human)4e-18triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407309826GWAS958802_Hpolyunsaturated fatty acid measurement QTL GWAS958802 (human)9e-22milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)191123547911235480Human
407255043GWAS904019_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS904019 (human)1e-08low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)191123547911235480Human
1581534BP76_HBlood pressure QTL 76 (human)20.001Blood pressurepulse pressure19116075902Human
1581535BP65_HBlood pressure QTL 65 (human)3.10.001Blood pressurepulse pressure19116075902Human
407241994GWAS890970_Hphosphatidylinositol measurement QTL GWAS890970 (human)4e-11phosphatidylinositol measurement191123547911235480Human
1298499UAE1_HUrinary albumin excretion QTL 1 (human)2.730.0009Urinary albumin excretionurine albumin:creatinine ratio (ACR)19116075902Human
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
407320210GWAS969186_Hlinoleic acid measurement QTL GWAS969186 (human)1e-15linoleic acid measurementblood free fatty acids level (CMO:0000117)191123547911235480Human
407133854GWAS782830_Hhigh density lipoprotein cholesterol measurement QTL GWAS782830 (human)7e-19high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407096408GWAS745384_Hphospholipids:total lipids ratio QTL GWAS745384 (human)3e-23phospholipids:total lipids ratio191123547911235480Human
407290714GWAS939690_Hhigh density lipoprotein cholesterol measurement QTL GWAS939690 (human)7e-67high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407311065GWAS960041_Hhigh density lipoprotein cholesterol measurement QTL GWAS960041 (human)1e-18high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407331750GWAS980726_Hfatty acid measurement QTL GWAS980726 (human)5e-15fatty acid measurement191123547911235480Human
1643451SLIPL6_HSerum lipid level QTL 6 (human)2.190.0008Lipid level19116075902Human
407129062GWAS778038_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS778038 (human)8e-16total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407137255GWAS786231_Hfree cholesterol in very large HDL measurement QTL GWAS786231 (human)2e-18free cholesterol in very large HDL measurement 191123547911235480Human
407253347GWAS902323_Homega-6 polyunsaturated fatty acid measurement QTL GWAS902323 (human)1e-20omega-6 polyunsaturated fatty acid measurement191123547911235480Human
407068395GWAS717371_Hchylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS717371 (human)4e-15chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)191123547911235480Human
407268652GWAS917628_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS917628 (human)8e-15triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407253933GWAS902909_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS902909 (human)5e-10low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)191123547911235480Human
407133174GWAS782150_Hesterified cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS782150 (human)2e-14esterified cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407319797GWAS968773_Homega-6 polyunsaturated fatty acid measurement QTL GWAS968773 (human)5e-20omega-6 polyunsaturated fatty acid measurement191123547911235480Human
407254132GWAS903108_Hhigh density lipoprotein cholesterol measurement QTL GWAS903108 (human)1e-197high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407310834GWAS959810_Hlinoleic acid measurement QTL GWAS959810 (human)2e-16linoleic acid measurementblood free fatty acids level (CMO:0000117)191123547911235480Human
407315185GWAS964161_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS964161 (human)2e-12cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191123547911235480Human
407075450GWAS724426_Hlevel of Phosphatidylinositol (18:0_18:2) in blood serum QTL GWAS724426 (human)0.0000002level of Phosphatidylinositol (18:0_18:2) in blood serum191123547911235480Human
407326846GWAS975822_Hfatty acid measurement QTL GWAS975822 (human)6e-17fatty acid measurement191123547911235480Human
407256572GWAS905548_Hfatty acid measurement QTL GWAS905548 (human)8e-10fatty acid measurement191123547911235480Human
2314591INSUL4_HInsulin level QTL 4 (human)3.80.000038Insulin levelfasting19116075902Human
1298476BP3_HBlood pressure QTL 3 (human)2.4Blood pressuresystolic19116075902Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS717371_H GCST90302171 Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals A 0.0924 4E-15 14.398 rs56322906 0.0719 chylomicron measurement (EFO:0008596)
very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS724426_H GCST90244494 Phosphatidylinositol (18:0_18:2) levels 4,642 European ancestry women A NR 2E-7 6.699 rs56322906 0.2406 PMID:36193934
GWAS745384_H GCST90269741 Phospholipids to total lipids in small HDL percentage (UKB data field 23644) 88,329 European ancestry individuals A 0.0348153 3E-23 22.523 rs56322906 0.124218 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS778038_H GCST90302126 Total cholesterol levels in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.0909 8E-16 15.097 rs56322906 0.0704 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS782150_H GCST90302128 Cholesterol esters in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.0908 2E-14 13.699 rs56322906 0.0668 esterified cholesterol measurement (EFO:0008589)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS782830_H GCST90302133 Concentration of very large HDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.0914 7E-19 18.155 rs56322906 0.0779 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS786231_H GCST90302130 Free cholesterol in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.0912 2E-18 17.699 rs56322906 0.0766 free cholesterol in very large HDL measurement (EFO:0022273)
 PMID:38448586
GWAS890970_H GCST90060946 Phosphatidylinositol(38:4)_[M-H]1- levels 5,662 Pakistani ancestry individuals T NR 4E-11 10.398 rs56322906 0.0827 phosphatidylinositol measurement (EFO:0010230)
 PMID:34503513
GWAS902323_H GCST90092933 Omega-6 fatty acid levels 115,006 European ancestry individuals G 0.964845 1E-20 20 rs56322906 0.101934 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35213538
GWAS902909_H GCST90092913 Phospholipids to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.964842 5E-10 9.302 rs56322906 0.0693064 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:35213538
GWAS903108_H GCST90239649 High density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 1E-197 197 rs56322906 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS904019_H GCST90092907 Cholesteryl esters to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.964842 1E-8 8 rs56322906 0.0632968 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
GWAS905548_H GCST90092928 Monounsaturated fatty acid levels 115,006 European ancestry individuals G 0.964845 8E-10 9.097 rs56322906 0.0680189 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS917628_H GCST90092829 Triglyceride levels in HDL 115,082 European ancestry individuals G 0.964842 8E-15 14.097 rs56322906 0.0852475 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS928724_H GCST90092902 Triglyceride levels in medium HDL 115,082 European ancestry individuals G 0.964842 4E-18 17.398 rs56322906 0.0953447 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS939690_H GCST90239652 High density lipoprotein cholesterol levels 1,320,016 European ancestry individuals A 0.0388898 7E-67 66.155 rs56322906 0.0791286 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:34887591
GWAS958802_H GCST90092939 Polyunsaturated fatty acid levels 115,006 European ancestry individuals G 0.964845 9E-22 21.046 rs56322906 0.104409 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:35213538
GWAS959810_H GCST90092880 Linoleic acid levels 115,006 European ancestry individuals G 0.964845 2E-16 15.699 rs56322906 0.0908691 linoleic acid measurement (EFO:0006807)
 PMID:35213538
GWAS960041_H GCST90179147 High-density lipoprotein levels (MTAG) 361,194 European ancestry individuals A NR 1E-18 18 rs56322906 0.0638 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36376304
GWAS964161_H GCST90092945 Cholesterol to total lipids ratio in small HDL 115,082 European ancestry individuals G 0.964842 2E-12 11.699 rs56322906 0.0775653 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS968773_H GCST90133364 Total omega-6 fatty acid levels 114,999 European ancestry individuals G 0.96 5E-20 19.302 rs56322906 0.1 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35692035
GWAS969186_H GCST90133363 Linoleic acid levels 114,999 European ancestry individuals G 0.96 1E-15 15 rs56322906 0.088 linoleic acid measurement (EFO:0006807)
 PMID:35692035
GWAS975822_H GCST90092987 Total fatty acid levels 115,006 European ancestry individuals G 0.964845 6E-17 16.222 rs56322906 0.0925886 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS980726_H GCST90092980 Saturated fatty acid levels 115,006 European ancestry individuals G 0.964845 5E-15 14.302 rs56322906 0.0865727 fatty acid measurement (EFO:0005110)
 PMID:35213538
None Available GCST90448615 HDL cholesterol levels 38,000 South Asian ancestry individuals A NR 2E-31 30.699 rs56322906 0.111 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:39414775
Database Acc Id Source(s)
GWAS Catalog GCST90302128 GWAS Catalog

RGD Curation Notes
Note Type Note Reference