GWAS779058_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS779058_H (low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS779058 (human)) Homo sapiens

Symbol: GWAS779058_H
Name: low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS779058 (human)
RGD ID: 407130082
Trait: low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 1.0E-14
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381234,715,469 - 234,715,470RGD_MAPPER_PIPELINEGRCh38
GRCh371234,851,216 - 234,851,217RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779058_HHumanblood low density lipoprotein cholesterol level  IAGPrs496800405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS779058_HHumanlow density lipoprotein cholesterol measurement  IAGPrs496800405850206 GWAS_CATALOGPMID:38448586
GWAS779058_HHumanphospholipids:total lipids ratio  IAGPrs496800405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
151673793LOC124904556uncharacterized LOC1249045561234709357234717579Human

Position Markers

Peak: (rs496800)
Human AssemblyChrPosition (strand)Source
GRCh381234,715,469 - 234,715,470RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407120757GWAS769733_Hcholesterol:total lipids ratio, cholesteryl esters:total lipids ratio QTL GWAS769733 (human)2e-16cholesterol:total lipids ratio, cholesteryl esters:total lipids ratio1234715469234715470Human
407276484GWAS925460_Htotal cholesterol measurement QTL GWAS925460 (human)4e-20total cholesterol measurementblood total cholesterol level (CMO:0000051)1234715469234715470Human
407091792GWAS740768_Hfree cholesterol in large LDL measurement QTL GWAS740768 (human)2e-22free cholesterol in large LDL measurement1234715469234715470Human
407126887GWAS775863_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS775863 (human)2e-15low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human
407124240GWAS773216_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS773216 (human)3e-14low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human
407128097GWAS777073_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS777073 (human)4e-23esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human
407276483GWAS925459_Htotal cholesterol measurement QTL GWAS925459 (human)2e-17total cholesterol measurementblood total cholesterol level (CMO:0000051)1234715469234715470Human
407130082GWAS779058_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS779058 (human)1e-14low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human
407096079GWAS745055_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS745055 (human)1e-16low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human
407147227GWAS796203_Hlow density lipoprotein cholesterol measurement QTL GWAS796203 (human)1e-13low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)1234715469234715470Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS740768_H GCST90302011 Free cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4571 2E-22 21.699 rs496800 0.0383 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:38448586
None Available GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4571 2E-22 21.699 rs496800 0.0386 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS745055_H GCST90302046 Cholesteryl esters to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4573 1E-16 16 rs496800 0.0325 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS769733_H GCST90302094 Cholesteryl esters to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4572 2E-16 15.699 rs496800 0.0324 cholesterol:total lipids ratio (EFO:0020943)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS773216_H GCST90302096 Free cholesterol to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4566 3E-14 13.523 rs496800 0.0309 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:38448586
GWAS775863_H GCST90302100 Phospholipids to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4565 2E-15 14.699 rs496800 0.032 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS777073_H GCST90302093 Cholesterol esters in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.457 4E-23 22.398 rs496800 0.0392 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS779058_H GCST90302052 Phospholipids to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.4565 1E-14 14 rs496800 0.031 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS796203_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A 0.477 1E-13 13 rs496800 0.035 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
None Available GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A NR 1E-16 16 rs496800 0.036 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS925459_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A 0.477 2E-17 16.699 rs496800 0.039 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS925460_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A NR 4E-20 19.398 rs496800 0.039 total cholesterol measurement (EFO:0004574)
 PMID:29507422
Database Acc Id Source(s)
GWAS Catalog GCST90302052 GWAS Catalog

RGD Curation Notes
Note Type Note Reference