GWAS773916_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS773916_H (sleep duration, high density lipoprotein cholesterol measurement QTL GWAS773916 (human)) Homo sapiens

Symbol: GWAS773916_H
Name: sleep duration, high density lipoprotein cholesterol measurement QTL GWAS773916 (human)
RGD ID: 407124940
Trait: sleep duration, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 3.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,448,389 - 58,448,390RGD_MAPPER_PIPELINEGRCh38
GRCh371558,740,588 - 58,740,589RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS773916_HHumanblood high density lipoprotein cholesterol level  IAGPrs8023503405850206Based on the EFO term IDGWAS_CATALOGPMID:31719535

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS773916_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs8023503405850206 GWAS_CATALOGPMID:31719535
GWAS773916_HHumansleep duration  IAGPrs8023503405850206 GWAS_CATALOGPMID:31719535
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736877LIPClipase C, hepatic type155843199158569844Human
11084824LIPC-AS1LIPC antisense RNA 1155843490158498735Human

Position Markers

Peak: (rs8023503)
Human AssemblyChrPosition (strand)Source
GRCh381558,448,389 - 58,448,390RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407198917GWAS847893_Hphosphatidylethanolamine measurement QTL GWAS847893 (human)3e-09phosphatidylethanolamine measurement155844838958448390Human
407198919GWAS847895_Hphosphatidylethanolamine measurement QTL GWAS847895 (human)1e-08phosphatidylethanolamine measurement155844838958448390Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407124940GWAS773916_Hsleep duration, high density lipoprotein cholesterol measurement QTL GWAS773916 (human)3e-12sleep duration, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155844838958448390Human
407196174GWAS845150_Hphosphatidylethanolamine measurement QTL GWAS845150 (human)1e-09phosphatidylethanolamine measurement155844838958448390Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS773916_H GCST009368 HDL cholesterol levels x long total sleep time interaction (2df test) 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls ? NR 3E-12 11.523 rs8023503 0.01504 sleep duration (EFO:0005271)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31719535
GWAS845150_H GCST90024597 Total Phosphatidylethanolamine levels 4,492 European ancestry individuals T NR 1E-9 9 rs8023503 0.533 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS847893_H GCST90024369 Phosphatidylethanolamine (18:0_20:4) levels 4,492 European ancestry individuals T NR 3E-9 8.523 rs8023503 0.517 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS847895_H GCST90024366 Phosphatidylethanolamine (18:0_18:2) levels 4,492 European ancestry individuals T NR 1E-8 8 rs8023503 0.497 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
Database Acc Id Source(s)
GWAS Catalog GCST009368 GWAS Catalog

RGD Curation Notes
Note Type Note Reference