GWAS765939_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS765939_H (total cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS765939 (human)) Homo sapiens

Symbol: GWAS765939_H
Name: total cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS765939 (human)
RGD ID: 407116963
Trait: total cholesterol measurement, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
blood total cholesterol level   (CMO:0000051)    
LOD Score: Not Available
P Value: 6.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381470,302,201 - 70,302,202RGD_MAPPER_PIPELINEGRCh38
GRCh371470,768,918 - 70,768,919RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS765939_HHumanblood low density lipoprotein cholesterol level  IAGPrs4902813405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586
GWAS765939_HHumanblood total cholesterol level  IAGPrs4902813405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS765939_HHumanlow density lipoprotein cholesterol measurement  IAGPrs4902813405850206 GWAS_CATALOGPMID:38448586
GWAS765939_HHumantotal cholesterol measurement  IAGPrs4902813405850206 GWAS_CATALOGPMID:38448586
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38614591LOC101928046uncharacterized LOC101928046147025481970315237Human
155756506LOC127827895OCT4-NANOG hESC enhancer GRCh37_chr14:70768308-70768998147030159170302281Human

Position Markers

Peak: (rs4902813)
Human AssemblyChrPosition (strand)Source
GRCh381470,302,201 - 70,302,202RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407122373GWAS771349_Htotal cholesterol in medium LDL QTL GWAS771349 (human)5e-10total cholesterol in medium LDL147030220170302202Human
407093751GWAS742727_Hfree cholesterol in large LDL measurement QTL GWAS742727 (human)3e-10free cholesterol in large LDL measurement147030220170302202Human
407098358GWAS747334_Hcholesterol esters in medium LDL measurement QTL GWAS747334 (human)2e-10total cholesterol in small LDL147030220170302202Human
407123362GWAS772338_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS772338 (human)5e-11esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)147030220170302202Human
407116963GWAS765939_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS765939 (human)6e-10total cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)147030220170302202Human
407081596GWAS730572_Hfree cholesterol in IDL measurement QTL GWAS730572 (human)1e-09free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)147030220170302202Human
407126283GWAS775259_Htotal lipids in small LDL QTL GWAS775259 (human)2e-09total lipids in small LDL147030220170302202Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS730572_H GCST90301979 Free cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8551 1E-9 9 rs4902813 0.0341 free cholesterol in IDL measurement (EFO:0022181)
 PMID:38448586
GWAS742727_H GCST90302011 Free cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8551 3E-10 9.523 rs4902813 0.0353 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:38448586
GWAS747334_H GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 2E-10 9.699 rs4902813 0.0356 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS765939_H GCST90301991 Total cholesterol levels in LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 6E-10 9.222 rs4902813 0.0347 total cholesterol measurement (EFO:0004574)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS771349_H GCST90302043 Total cholesterol in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 5E-10 9.302 rs4902813 0.0349 total cholesterol in medium LDL (EFO:0022185)
 PMID:38448586
GWAS772338_H GCST90302093 Cholesterol esters in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 5E-11 10.302 rs4902813 0.0369 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS775259_H GCST90302097 Total lipids in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 2E-9 8.699 rs4902813 0.0339 total lipids in small LDL (EFO:0022168)
 PMID:38448586
None Available GCST90302091 Total Cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.8552 2E-10 9.699 rs4902813 0.0359 total cholesterol in small LDL (EFO:0022179)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90301991 GWAS Catalog

RGD Curation Notes
Note Type Note Reference