GWAS759457_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS759457_H (eosinophil count QTL GWAS759457 (human)) Homo sapiens

Symbol: GWAS759457_H
Name: eosinophil count QTL GWAS759457 (human)
RGD ID: 407110481
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 8.0E-22
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38112,186,118 - 12,186,119RGD_MAPPER_PIPELINEGRCh38
GRCh37112,246,175 - 12,246,176RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS759457_HHumanblood eosinophil count  IAGPrs474247405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS759457_HHumaneosinophil quantity  IAGPrs474247405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS759457_HHumaneosinophil count  IAGPrs474247405850206 GWAS_CATALOGPMID:30595370
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1298224TNFRSF1BTNF receptor superfamily member 1B11216699112209220Human

Position Markers

Peak: (rs474247)
Human AssemblyChrPosition (strand)Source
GRCh38112,186,118 - 12,186,119RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406939731GWAS588707_Heosinophil percentage of leukocytes QTL GWAS588707 (human)6e-17eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)11218611812186119Human
407110481GWAS759457_Heosinophil count QTL GWAS759457 (human)8e-22eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)11218611812186119Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407058349GWAS707325_Heosinophil count QTL GWAS707325 (human)9e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)11218611812186119Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS588707_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals T 0.21777 6E-17 16.222 rs474247 0.023184242 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS707325_H GCST90002381 Eosinophil counts 408,112 British individuals T 0.217779 9E-18 17.046 rs474247 0.023802869 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS759457_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 8E-22 21.097 rs474247 N/A eosinophil count (EFO:0004842)
 PMID:30595370
Database Acc Id Source(s)
GWAS Catalog GCST007065 GWAS Catalog

RGD Curation Notes
Note Type Note Reference