GWAS747432_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS747432_H (2'-O-methylcytidine measurement QTL GWAS747432 (human)) Homo sapiens

Symbol: GWAS747432_H
Name: 2'-O-methylcytidine measurement QTL GWAS747432 (human)
RGD ID: 407098456
Trait: 2'-O-methylcytidine measurement
LOD Score: Not Available
P Value: 2.0E-22
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38120,589,096 - 20,589,097RGD_MAPPER_PIPELINEGRCh38
GRCh37120,915,589 - 20,915,590RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS747432_HHuman2'-O-methylcytidine measurement  IAGPrs3215400405850206 GWAS_CATALOGPMID:37253714
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1322377CDAcytidine deaminase12058909720618903Human

Position Markers

Peak: (rs3215400)
Human AssemblyChrPosition (strand)Source
GRCh38120,589,096 - 20,589,097RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407334739GWAS983715_Hplatelet count QTL GWAS983715 (human)1e-08platelet quantity (VT:0003179)platelet count (CMO:0000029)12058909620589097Human
407098456GWAS747432_H2'-O-methylcytidine measurement QTL GWAS747432 (human)2e-222'-O-methylcytidine measurement12058909620589097Human
407305725GWAS954701_Hserum metabolite measurement QTL GWAS954701 (human)9e-15serum metabolite measurement12058909620589097Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS747432_H GCST90300411 Metabolite levels (2'-O-methylcytidine) 6,160 European, Hispanic or African American individuals T 0.5407 2E-22 21.699 rs3215400 0.177 2'-O-methylcytidine measurement (EFO:0800635)
 PMID:37253714
GWAS954701_H GCST012020 Serum metabolite levels 3,926 Hispanic/Latino individuals TC 0.47804 9E-15 14.046 rs3215400 0.175 serum metabolite measurement (EFO:0005653)
 PMID:33031748
GWAS983715_H GCST90018969 Platelet count 350,474 European ancestry individuals, 148,623 East Asian ancestry individuals T NR 1E-8 8 rs3215400 0.0109 platelet count (EFO:0004309)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90300411 GWAS Catalog

RGD Curation Notes
Note Type Note Reference