GWAS741744_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS741744_H (mean corpuscular hemoglobin QTL GWAS741744 (human)) Homo sapiens

Symbol: GWAS741744_H
Name: mean corpuscular hemoglobin QTL GWAS741744 (human)
RGD ID: 407092768
Trait: mean corpuscular hemoglobin
Measurement Type: mean corpuscular hemoglobin   (CMO:0000290)    
LOD Score: Not Available
P Value: 5.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38317,056,907 - 17,056,908RGD_MAPPER_PIPELINEGRCh38
GRCh37317,098,399 - 17,098,400RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS741744_HHumanmean corpuscular hemoglobin  IAGPrs116577908405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS741744_HHumanmean corpuscular hemoglobin  IAGPrs116577908405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1314267PLCL2phospholipase C like 231688495517090606Human

Position Markers

Peak: (rs116577908)
Human AssemblyChrPosition (strand)Source
GRCh38317,056,907 - 17,056,908RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406965937GWAS614913_Herythrocyte count QTL GWAS614913 (human)3e-23erythrocyte countred blood cell count (CMO:0000025)31705690717056908Human
407131429GWAS780405_Hmean corpuscular volume QTL GWAS780405 (human)9e-28mean corpuscular volumemean corpuscular volume (CMO:0000038)31705690717056908Human
407092768GWAS741744_Hmean corpuscular hemoglobin QTL GWAS741744 (human)5e-20mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)31705690717056908Human
406962614GWAS611590_Hmean corpuscular hemoglobin QTL GWAS611590 (human)6e-26mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)31705690717056908Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
407135294GWAS784270_Herythrocyte count QTL GWAS784270 (human)2e-20erythrocyte countred blood cell count (CMO:0000025)31705690717056908Human
407094094GWAS743070_Hmean reticulocyte volume QTL GWAS743070 (human)6e-27reticulocyte morphology trait (VT:0002424)mean corpuscular volume (CMO:0000038)31705690717056908Human
407135642GWAS784618_Hobsolete_red blood cell distribution width QTL GWAS784618 (human)5e-09obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)31705690717056908Human
407132475GWAS781451_Hmean corpuscular volume QTL GWAS781451 (human)3e-25mean corpuscular volumemean corpuscular volume (CMO:0000038)31705690717056908Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS611590_H GCST007068 Mean corpuscular hemoglobin approximately 443,000 European ancestry individuals ? NR 6E-26 25.222 rs116577908 N/A mean corpuscular hemoglobin (EFO:0004527)
 PMID:30595370
GWAS614913_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 3E-23 22.523 rs116577908 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS741744_H GCST90002390 Mean corpuscular hemoglobin 408,112 British individuals G 0.01093 5E-20 19.302 rs116577908 0.108376645 mean corpuscular hemoglobin (EFO:0004527)
 PMID:32888494
GWAS743070_H GCST90002396 Mean reticulocyte volume 408,112 British individuals G 0.010925 6E-27 26.222 rs116577908 0.12992105 mean reticulocyte volume (EFO:0010701)
 PMID:32888494
GWAS780405_H GCST90002392 Mean corpuscular volume 408,112 British individuals G 0.010934 9E-28 27.046 rs116577908 0.125877 mean corpuscular volume (EFO:0004526)
 PMID:32888494
GWAS781451_H GCST90002397 Mean spheric corpuscular volume 408,112 British individuals G 0.010935 3E-25 24.523 rs116577908 0.124177925 mean corpuscular volume (EFO:0004526)
 PMID:32888494
GWAS784270_H GCST90002403 Red blood cell count 408,112 British individuals G 0.010929 2E-20 19.699 rs116577908 0.10983117 erythrocyte count (EFO:0004305)
 PMID:32888494
None Available GCST007074 Red cell distribution width approximately 445,000 European ancestry individuals ? NR 5E-9 8.302 rs116577908 N/A Red cell distribution width (EFO:0009188)
 PMID:30595370
Database Acc Id Source(s)
GWAS Catalog GCST90002390 GWAS Catalog

RGD Curation Notes
Note Type Note Reference