GWAS738027_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS738027_H (intermediate density lipoprotein measurement QTL GWAS738027 (human)) Homo sapiens

Symbol: GWAS738027_H
Name: intermediate density lipoprotein measurement QTL GWAS738027 (human)
RGD ID: 407089051
Trait: intermediate density lipoprotein measurement
Measurement Type: blood intermediate density lipoprotein cholesterol level   (CMO:0001562)    
blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 2.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382017,863,324 - 17,863,325RGD_MAPPER_PIPELINEGRCh38
GRCh372017,843,968 - 17,843,969RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS738027_HHumanblood intermediate density lipoprotein cholesterol level  IAGPrs2618568405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586
GWAS738027_HHumanblood low density lipoprotein cholesterol level  IAGPrs2618568405850206Based on the EFO term IDGWAS_CATALOGPMID:38448586

Experimental Factor Annotations    Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs2618568)
Human AssemblyChrPosition (strand)Source
GRCh382017,863,324 - 17,863,325RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407120388GWAS769364_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS769364 (human)9e-17cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)201786332417863325Human
407128773GWAS777749_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS777749 (human)5e-22low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
407122433GWAS771409_Hphospholipids in small HDL measurement QTL GWAS771409 (human)2e-10phospholipids in small HDL measurement 201786332417863325Human
407075396GWAS724372_Hesterified cholesterol measurement, intermediate density lipoprotein measurement QTL GWAS724372 (human)7e-22esterified cholesterol measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786332417863325Human
407077577GWAS726553_Hapolipoprotein B measurement QTL GWAS726553 (human)1e-14apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)201786332417863325Human
407154249GWAS803225_Hcholesterol in very small VLDL measurement QTL GWAS803225 (human)2e-14cholesterol in very small VLDL measurement 201786332417863325Human
407081228GWAS730204_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS730204 (human)4e-18cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)201786332417863325Human
407077971GWAS726947_Htotal cholesterol in IDL QTL GWAS726947 (human)2e-22total cholesterol in IDL201786332417863325Human
406904785GWAS553761_Htotal cholesterol measurement QTL GWAS553761 (human)5e-10total cholesterol measurementblood total cholesterol level (CMO:0000051)201786332417863325Human
407071312GWAS720288_Hapolipoprotein A 1 measurement, apolipoprotein B measurement QTL GWAS720288 (human)1e-12apolipoprotein A 1 measurement, apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)201786332417863325Human
407083798GWAS732774_Hphospholipids in medium LDL measurement QTL GWAS732774 (human)3e-18phospholipids in medium LDL measurementblood low density lipoprotein phospholipid level (CMO:0001568)201786332417863325Human
407117969GWAS766945_Htotal lipids in IDL QTL GWAS766945 (human)3e-21total lipids in IDL201786332417863325Human
407084758GWAS733734_Hphospholipids in IDL measurement QTL GWAS733734 (human)2e-21phospholipids in IDL measurementblood intermediate density lipoprotein phospholipid level (CMO:0001574)201786332417863325Human
407089051GWAS738027_Hintermediate density lipoprotein measurement QTL GWAS738027 (human)2e-20cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
407162841GWAS811817_Hfree cholesterol in very small VLDL measurement QTL GWAS811817 (human)3e-14total lipids in very small VLDL measurement201786332417863325Human
407054109GWAS703085_Hvery low density lipoprotein cholesterol measurement QTL GWAS703085 (human)3e-13very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786332417863325Human
1643385BW311_HBody weight QTL 311 (human)3.310.0001Body fat amount20734547523289549Human
406887137GWAS536113_Htotal cholesterol measurement QTL GWAS536113 (human)1e-09total cholesterol measurementblood total cholesterol level (CMO:0000051)201786332417863325Human
406887461GWAS536437_Hlow density lipoprotein cholesterol measurement QTL GWAS536437 (human)7e-15low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
407055716GWAS704692_Hphospholipids in VLDL measurement QTL GWAS704692 (human)3e-19cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
407120611GWAS769587_Hremnant cholesterol measurement QTL GWAS769587 (human)2e-13remnant cholesterol measurement201786332417863325Human
407098347GWAS747323_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS747323 (human)2e-18cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
406887465GWAS536441_Htotal cholesterol measurement QTL GWAS536441 (human)2e-12total cholesterol measurementblood total cholesterol level (CMO:0000051)201786332417863325Human
407095279GWAS744255_Hfree cholesterol in large LDL measurement QTL GWAS744255 (human)4e-23free cholesterol in large LDL measurement201786332417863325Human
1643383BW312_HBody weight QTL 312 (human)2.920.0004Body fat amountpercent fat20734547523289549Human
406886574GWAS535550_Htotal cholesterol measurement QTL GWAS535550 (human)1e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)201786332417863325Human
406886575GWAS535551_Htotal cholesterol measurement QTL GWAS535551 (human)5e-09total cholesterol measurementblood total cholesterol level (CMO:0000051)201786332417863325Human
407082161GWAS731137_Hfree cholesterol in IDL measurement QTL GWAS731137 (human)3e-22free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)201786332417863325Human
407119155GWAS768131_Hphospholipids in large LDL measurement QTL GWAS768131 (human)1e-21phospholipids in large LDL measurementblood low density lipoprotein phospholipid level (CMO:0001568)201786332417863325Human
407152253GWAS801229_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS801229 (human)7e-14very low density lipoprotein cholesterol measurement, esterified cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786332417863325Human
406889595GWAS538571_Hlow density lipoprotein cholesterol measurement QTL GWAS538571 (human)6e-14low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
406889597GWAS538573_Hlow density lipoprotein cholesterol measurement QTL GWAS538573 (human)8e-15low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)201786332417863325Human
407143033GWAS792009_Hvery low density lipoprotein cholesterol measurement, esterified cholesterol measurement QTL GWAS792009 (human)1e-10very low density lipoprotein cholesterol measurement, esterified cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)201786332417863325Human
407121017GWAS769993_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS769993 (human)2e-19phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)201786332417863325Human
407124794GWAS773770_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS773770 (human)4e-13free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)201786332417863325Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS535550_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C 0.396 1E-8 8 rs2618568 0.028 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS535551_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C NR 5E-9 8.302 rs2618568 0.026 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS536113_H GCST006614 Total cholesterol levels 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals A 0.6004 1E-9 9 rs2618568 0.0186 total cholesterol measurement (EFO:0004574)
 PMID:30275531
GWAS536437_H GCST002898 LDL cholesterol up 62,166 European ancestry individuals C 0.37 7E-15 14.155 rs2618568 0.049 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:25961943
GWAS536441_H GCST002896 Cholesterol, total up to 62,166 European ancestry individuals C 0.37 2E-12 11.699 rs2618568 0.044 total cholesterol measurement (EFO:0004574)
 PMID:25961943
GWAS538571_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C 0.396 6E-14 13.222 rs2618568 0.038 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS538573_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C NR 8E-15 14.097 rs2618568 0.035 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS553761_H GCST90244655 Total cholesterol levels 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals ? NR 5E-10 9.302 rs2618568 1.6065209 total cholesterol measurement (EFO:0004574)
 PMID:36220816
GWAS703085_H GCST90302157 Concentration of very small VLDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6035 3E-13 12.523 rs2618568 0.0304 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:38448586
GWAS704692_H GCST90302158 Phospholipids in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 3E-19 18.523 rs2618568 0.0375 phospholipids in VLDL measurement (EFO:0022301)
 PMID:38448586
GWAS720288_H GCST90301947 Ratio of apolipoprotein B to apolipoprotein A1 levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6029 1E-12 12 rs2618568 0.0297 apolipoprotein A 1 measurement (EFO:0004614)
apolipoprotein B measurement (EFO:0004615)
 PMID:38448586
GWAS724372_H GCST90301977 Cholesterol esters in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 7E-22 21.155 rs2618568 0.0401 esterified cholesterol measurement (EFO:0008589)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
GWAS726553_H GCST90301946 Apolipoprotein B levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 1E-14 14 rs2618568 0.0321 apolipoprotein B measurement (EFO:0004615)
 PMID:38448586
GWAS726947_H GCST90301975 Total Cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 2E-22 21.699 rs2618568 0.0406 total cholesterol in IDL (EFO:0022184)
 PMID:38448586
GWAS730204_H GCST90302048 Free cholesterol to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6048 4E-18 17.398 rs2618568 0.0351 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:38448586
GWAS731137_H GCST90301979 Free cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 3E-22 21.523 rs2618568 0.0405 free cholesterol in IDL measurement (EFO:0022181)
 PMID:38448586
GWAS732774_H GCST90302051 Phospholipids in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.603 3E-18 17.523 rs2618568 0.0365 phospholipids in medium LDL measurement (EFO:0022183)
 PMID:38448586
GWAS733734_H GCST90301983 Phospholipids in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 2E-21 20.699 rs2618568 0.0397 phospholipids in IDL measurement (EFO:0022164)
 PMID:38448586
None Available GCST90302008 Total cholesterol to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 3E-19 18.523 rs2618568 0.0376 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS738027_H GCST90301982 Concentration of IDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 2E-20 19.699 rs2618568 0.0387 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
None Available GCST90302010 Cholesteryl esters to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 2E-20 19.699 rs2618568 0.0388 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS744255_H GCST90302011 Free cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 4E-23 22.398 rs2618568 0.0414 free cholesterol in large LDL measurement (EFO:0022176)
 PMID:38448586
GWAS747323_H GCST90302044 Total cholesterol to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6034 2E-18 17.699 rs2618568 0.0364 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS766945_H GCST90301981 Total lipids in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6032 3E-21 20.523 rs2618568 0.0396 total lipids in IDL (EFO:0022161)
 PMID:38448586
GWAS768131_H GCST90302015 Phospholipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6031 1E-21 21 rs2618568 0.04 phospholipids in large LDL measurement (EFO:0022174)
 PMID:38448586
GWAS769364_H GCST90302080 Total cholesterol to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6034 9E-17 16.046 rs2618568 0.0345 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS769587_H GCST90302074 Remnant cholesterol (non-HDL, non-LDL -cholesterol) 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6033 2E-13 12.699 rs2618568 0.0308 remnant cholesterol measurement (EFO:0010815)
 PMID:38448586
GWAS769993_H GCST90302088 Phospholipids to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6048 2E-19 18.699 rs2618568 0.0363 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
None Available GCST90302082 Cholesteryl esters to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6034 4E-18 17.398 rs2618568 0.036 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
GWAS771409_H GCST90302087 Phospholipids in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6034 2E-10 9.699 rs2618568 0.0265 phospholipids in small HDL measurement (EFO:0022296)
 PMID:38448586
GWAS773770_H GCST90302084 Free cholesterol to total lipids ratio in small HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6056 4E-13 12.398 rs2618568 0.0288 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:38448586
None Available GCST90302092 Total cholesterol to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6034 2E-20 19.699 rs2618568 0.0386 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS777749_H GCST90302100 Phospholipids to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6049 5E-22 21.302 rs2618568 0.0389 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS792009_H GCST90302106 Cholesterol esters in small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6035 1E-10 10 rs2618568 0.0266 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS801229_H GCST90302152 Cholesterol esters in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6038 7E-14 13.155 rs2618568 0.0309 very low density lipoprotein cholesterol measurement (EFO:0008317)
esterified cholesterol measurement (EFO:0008589)
 PMID:38448586
GWAS803225_H GCST90302150 Total cholesterol in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6037 2E-14 13.699 rs2618568 0.0318 cholesterol in very small VLDL measurement (EFO:0022231)
 PMID:38448586
GWAS811817_H GCST90302154 Free cholesterol in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6036 3E-14 13.523 rs2618568 0.0315 free cholesterol in very small VLDL measurement (EFO:0022275)
 PMID:38448586
None Available GCST90302156 Total lipids in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.6035 3E-14 13.523 rs2618568 0.0315 total lipids in very small VLDL measurement (EFO:0022156)
 PMID:38448586
Database Acc Id Source(s)
GWAS Catalog GCST90301982 GWAS Catalog
  GCST90302010 GWAS Catalog
  GCST90302092 GWAS Catalog

RGD Curation Notes
Note Type Note Reference