GWAS736496_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS736496_H (high density lipoprotein cholesterol measurement QTL GWAS736496 (human)) Homo sapiens

Symbol: GWAS736496_H
Name: high density lipoprotein cholesterol measurement QTL GWAS736496 (human)
RGD ID: 407087520
Trait: high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 4.0E-30
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,395,404 - 58,395,405RGD_MAPPER_PIPELINEGRCh38
GRCh371558,687,603 - 58,687,604RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS736496_HHumanblood high density lipoprotein cholesterol level  IAGPrs174418405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS736496_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs174418405850206 GWAS_CATALOGPMID:36764567
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs174418)
Human AssemblyChrPosition (strand)Source
GRCh381558,395,404 - 58,395,405RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407137764GWAS786740_Hsexual dimorphism measurement QTL GWAS786740 (human)1e-23sexual dimorphism measurement155839540458395405Human
407314183GWAS963159_Htriacylglycerol 54:2 measurement QTL GWAS963159 (human)1e-12blood triglyceride amount (VT:0002644)155839540458395405Human
407268838GWAS917814_Hlipid measurement QTL GWAS917814 (human)2e-08blood phospholipid amount (VT:0006084)blood lipid measurement (CMO:0000050)155839540458395405Human
407088385GWAS737361_Hcholesterol in small HDL measurement QTL GWAS737361 (human)4e-32cholesterol in small HDL measurement 155839540458395405Human
407087520GWAS736496_Hhigh density lipoprotein cholesterol measurement QTL GWAS736496 (human)4e-30high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155839540458395405Human
407034724GWAS683700_Hdocosahexaenoic acid to total fatty acids percentage QTL GWAS683700 (human)5e-37docosahexaenoic acid to total fatty acids percentage 155839540458395405Human
407092426GWAS741402_H1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement QTL GWAS741402 (human)1e-111-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement155839540458395405Human
407312269GWAS961245_Hdiglyceride measurement QTL GWAS961245 (human)5e-10diglyceride measurement155839540458395405Human
407329517GWAS978493_Hdiglyceride measurement QTL GWAS978493 (human)3e-10diglyceride measurement155839540458395405Human
407291468GWAS940444_Hphosphatidylethanolamine measurement QTL GWAS940444 (human)2e-47phosphatidylethanolamine measurement155839540458395405Human
407267085GWAS916061_Hlipid measurement QTL GWAS916061 (human)0.0000008lipid measurementblood lipid measurement (CMO:0000050)155839540458395405Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407103694GWAS752670_H2-stearoyl-GPE (18:0) measurement QTL GWAS752670 (human)4e-132-stearoyl-GPE (18:0) measurement155839540458395405Human
407127913GWAS776889_Hcomplex trait QTL GWAS776889 (human)3e-33complex trait155839540458395405Human
407321066GWAS970042_Hphosphatidylethanolamine measurement QTL GWAS970042 (human)7e-38phosphatidylethanolamine measurement155839540458395405Human
407267401GWAS916377_Hlipid measurement QTL GWAS916377 (human)0.0000006lipid measurementblood lipid measurement (CMO:0000050)155839540458395405Human
407312275GWAS961251_Hdiglyceride measurement QTL GWAS961251 (human)8e-09diglyceride measurement155839540458395405Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407073658GWAS722634_Hcomplex trait QTL GWAS722634 (human)1e-38complex trait155839540458395405Human
407325758GWAS974734_Hdiglyceride measurement QTL GWAS974734 (human)3e-08diglyceride measurement155839540458395405Human
407269372GWAS918348_Hlipid measurement QTL GWAS918348 (human)0.000003lipid measurementblood lipid measurement (CMO:0000050)155839540458395405Human
407198168GWAS847144_Hlipid measurement QTL GWAS847144 (human)0.000005lipid measurementblood lipid measurement (CMO:0000050)155839540458395405Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS683700_H GCST90269554 Docosahexaenoic acid to total fatty acids percentage (UKB data field 23457) 88,268 European ancestry individuals T 0.40325 5E-37 36.302 rs174418 0.0593257 docosahexaenoic acid to total fatty acids percentage (EFO:0022262)
 PMID:36764567
GWAS722634_H GCST90270119 Multi-trait sum score 141,980 European ancestry males ? NR 1E-38 38 rs174418 N/A complex trait (EFO:0010578)
 PMID:37277458
GWAS736496_H GCST90269669 Concentration of small HDL particles (UKB data field 23572) 88,329 European ancestry individuals T 0.40326 4E-30 29.398 rs174418 0.0551554 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:36764567
GWAS737361_H GCST90269672 Cholesterol in small HDL (UKB data field 23575) 88,329 European ancestry individuals T 0.40326 4E-32 31.398 rs174418 0.0569139 cholesterol in small HDL measurement (EFO:0022226)
 PMID:36764567
GWAS741402_H GCST90200083 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) levels 8,266 European ancestry individuals C 0.594647 1E-11 11 rs174418 0.108969 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement (EFO:0800466)
 PMID:36635386
GWAS752670_H GCST90199928 2-stearoyl-GPE (18:0) levels 8,073 European ancestry individuals C 0.59371 4E-13 12.398 rs174418 0.118161 2-stearoyl-GPE (18:0) measurement (EFO:0800343)
 PMID:36635386
GWAS776889_H GCST90270117 Multi-trait sum score 161,906 European ancestry females ? NR 3E-33 32.523 rs174418 N/A complex trait (EFO:0010578)
 PMID:37277458
GWAS786740_H GCST90270116 Multi-trait sex score 161,906 European ancestry females ? NR 1E-23 23 rs174418 N/A sexual dimorphism measurement (EFO:0021796)
 PMID:37277458
GWAS847144_H GCST90133752 1-stearoyl-GPE (18:0) levels in elite athletes 490 individuals ? NR 0.000005 5.302 rs174418 0.27807313 lipid measurement (EFO:0004529)
 PMID:31882771
GWAS916061_H GCST90133722 1-palmitoyl-2-linoleoyl-GPE (16:0/18:2) levels in elite athletes 490 individuals ? NR 8E-7 6.097 rs174418 0.30229095 lipid measurement (EFO:0004529)
 PMID:31882771
GWAS916377_H GCST90133733 1-palmitoyl-GPE (16:0) levels in elite athletes 490 individuals ? NR 6E-7 6.222 rs174418 0.30866852 lipid measurement (EFO:0004529)
 PMID:31882771
GWAS917814_H GCST90133716 1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) levels in elite athletes 490 individuals ? NR 2E-8 7.699 rs174418 0.3393429 lipid measurement (EFO:0004529)
 PMID:31882771
GWAS918348_H GCST90133725 1-palmitoyl-2-oleoyl-GPE (16:0/18:1) levels in elite athletes 490 individuals ? NR 0.000003 5.523 rs174418 0.29001138 lipid measurement (EFO:0004529)
 PMID:31882771
GWAS940444_H GCST90024367 Phosphatidylethanolamine (18:0_20:3) (a) levels 4,492 European ancestry individuals C NR 2E-47 46.699 rs174418 0.323 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS961245_H GCST90024573 Alkyldiacylglycerol (O-50:1) [NL-16:0] levels 4,492 European ancestry individuals C NR 5E-10 9.302 rs174418 0.14 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS961251_H GCST90024575 Alkyldiacylglycerol (O-52:2) [NL-16:0] levels 4,492 European ancestry individuals C NR 8E-9 8.097 rs174418 0.129 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS963159_H GCST90024564 Triacylglycerol (54:2) [NL-18:0] levels 4,492 European ancestry individuals C NR 1E-12 12 rs174418 0.159 triacylglycerol 54:2 measurement (EFO:0010420)
 PMID:35668104
None Available GCST90024486 Phosphatidylserine (40:6) levels 4,492 European ancestry individuals C NR 2E-8 7.699 rs174418 0.125 phosphatidylserines measurement (EFO:0020049)
 PMID:35668104
GWAS970042_H GCST90025606 Phosphatidylethanolamine (18:0_20:3) (a) levels 4,492 European ancestry individuals C NR 7E-38 37.155 rs174418 0.288 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35668104
GWAS974734_H GCST90024086 Diacylglycerol (18:0_18:1) levels 4,492 European ancestry individuals C NR 3E-8 7.523 rs174418 0.125 diglyceride measurement (EFO:0010223)
 PMID:35668104
GWAS978493_H GCST90024606 Total Alkyldiacylglycerol levels 4,492 European ancestry individuals C NR 3E-10 9.523 rs174418 0.142 diglyceride measurement (EFO:0010223)
 PMID:35668104
Database Acc Id Source(s)
GWAS Catalog GCST90269669 GWAS Catalog

RGD Curation Notes
Note Type Note Reference