GWAS733517_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS733517_H (cholesteryl esters to total lipids in medium LDL percentage QTL GWAS733517 (human)) Homo sapiens

Symbol: GWAS733517_H
Name: cholesteryl esters to total lipids in medium LDL percentage QTL GWAS733517 (human)
RGD ID: 407084541
Trait: cholesteryl esters to total lipids in medium LDL percentage
LOD Score: Not Available
P Value: 9.0E-82
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38819,962,922 - 19,962,923RGD_MAPPER_PIPELINEGRCh38
GRCh37819,820,433 - 19,820,434RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS733517_HHumancholesteryl esters to total lipids in medium LDL percentage  IAGPrs12679834405850206 GWAS_CATALOGPMID:36764567
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
70836LPLlipoprotein lipase81993925319967259Human

Position Markers

Peak: (rs12679834)
Human AssemblyChrPosition (strand)Source
GRCh38819,962,922 - 19,962,923RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407111972GWAS760948_Htriglycerides in HDL measurement QTL GWAS760948 (human)1e-100triglycerides in HDL measurement 81996292219962923Human
1298482BP2_HBlood pressure QTL 2 (human)1.8Blood pressurediastolic8695325632953256Human
407281829GWAS930805_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS930805 (human)8e-118triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)81996292219962923Human
407266629GWAS915605_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS915605 (human)2e-137triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)81996292219962923Human
407088935GWAS737911_Htriglycerides to total lipids in medium HDL percentage QTL GWAS737911 (human)1e-192triglycerides to total lipids in medium HDL percentage 81996292219962923Human
407164161GWAS813137_Hdiacylglycerol 34:2 measurement QTL GWAS813137 (human)2e-26milk diacylglycerol amount (VT:0010385)blood triglyceride level (CMO:0000118)81996292219962923Human
407029476GWAS678452_Hlinoleic acid measurement QTL GWAS678452 (human)8e-10linoleic acid measurementblood free fatty acids level (CMO:0000117)81996292219962923Human
407195373GWAS844349_Htriglyceride measurement QTL GWAS844349 (human)3e-26sphingomyelin measurementblood triglyceride level (CMO:0000118)81996292219962923Human
407383841GWAS1032817_Hobsolete_red blood cell distribution width QTL GWAS1032817 (human)9e-60obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)81996292219962923Human
407023502GWAS672478_Htriglycerides in medium HDL measurement QTL GWAS672478 (human)4e-86triglycerides in medium HDL measurement 81996292219962923Human
407129333GWAS778309_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS778309 (human)1e-18cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81996292219962923Human
407085712GWAS734688_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS734688 (human)2e-15cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81996292219962923Human
406927477GWAS576453_Htriglyceride measurement QTL GWAS576453 (human)4e-51triglyceride measurementblood triglyceride level (CMO:0000118)81996292219962923Human
407058260GWAS707236_Hfatty acid change measurement QTL GWAS707236 (human)3e-19fatty acid change measurement81996292219962923Human
407123059GWAS772035_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS772035 (human)1e-14cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)81996292219962923Human
1558703SCL6_HSerum cholesterol level QTL 1 (human)1.2Lipid levelHDL cholesterol81246863538468635Human
407294492GWAS943468_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS943468 (human)9e-108low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)81996292219962923Human
407081758GWAS730734_Hcholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS730734 (human)1e-30cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)81996292219962923Human
407084541GWAS733517_Hcholesteryl esters to total lipids in medium LDL percentage QTL GWAS733517 (human)9e-82cholesteryl esters to total lipids in medium LDL percentage 81996292219962923Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS576453_H GCST90244679 Triglyceride levels in type 2 diabetes 21,176 European ancestry individuals ? NR 4E-51 50.398 rs12679834 N/A triglyceride measurement (EFO:0004530)
 PMID:36269708
GWAS672478_H GCST90269668 Triglycerides in medium HDL (UKB data field 23571) 88,329 European ancestry individuals C 0.100861 4E-86 85.398 rs12679834 0.151894 triglycerides in medium HDL measurement (EFO:0022321)
 PMID:36764567
GWAS678452_H GCST90269546 Linoleic acid levels (UKB data field 23449) 88,268 European ancestry individuals C 0.10084 8E-10 9.097 rs12679834 0.0472185 linoleic acid measurement (EFO:0006807)
 PMID:36764567
GWAS707236_H GCST90301958 Estimated description of fatty acid chain length not actual carbon number 74,743 Non-Finnish European ancestry individuals T 0.8953 3E-19 18.523 rs12679834 0.0852 fatty acid change measurement (EFO:0020875)
 PMID:38448586
GWAS733517_H GCST90269718 Cholesteryl esters to total lipids in medium LDL percentage (UKB data field 23621) 88,329 European ancestry individuals C 0.100861 9E-82 81.046 rs12679834 0.149459 cholesteryl esters to total lipids in medium LDL percentage (EFO:0022252)
 PMID:36764567
GWAS734688_H GCST90302008 Total cholesterol to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.9 2E-15 14.699 rs12679834 0.0525 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS737911_H GCST90269740 Triglycerides to total lipids in medium HDL percentage (UKB data field 23643) 88,329 European ancestry individuals C 0.100861 1E-192 192 rs12679834 0.223523 triglycerides to total lipids in medium HDL percentage (EFO:0022333)
 PMID:36764567
GWAS760948_H GCST90269507 Triglycerides in HDL (UKB data field 23410) 88,329 European ancestry individuals C 0.100861 1E-100 100 rs12679834 0.164043 triglycerides in HDL measurement (EFO:0022317)
 PMID:36764567
GWAS772035_H GCST90302044 Total cholesterol to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.8999 1E-14 14 rs12679834 0.0509 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS778309_H GCST90302092 Total cholesterol to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.8999 1E-18 18 rs12679834 0.0579 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS813137_H GCST90060606 Diacylglycerol(34:2)_[M+H-H2O]1+ levels 5,662 Pakistani ancestry individuals G NR 2E-26 25.699 rs12679834 0.0722 diacylglycerol 34:2 measurement (EFO:0010353)
 PMID:34503513
None Available GCST90060607 Diacylglycerol(34:1)_[M+H-H2O]1+ levels 5,662 Pakistani ancestry individuals G NR 2E-26 25.699 rs12679834 0.0786 diacylglycerol 34:1 measurement (EFO:0010352)
 PMID:34503513
GWAS844349_H GCST90060955 Triacylglycerol(53:2)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals T NR 3E-26 25.523 rs12679834 0.0786 triglyceride measurement (EFO:0004530)
 PMID:34503513
None Available GCST90060952 Triacylglycerol(53:3)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 2E-26 25.699 rs12679834 0.1325 triglyceride measurement (EFO:0004530)
 PMID:34503513
None Available GCST007074 Red cell distribution width approximately 445,000 European ancestry individuals ? NR 9E-60 59.046 rs12679834 N/A Red cell distribution width (EFO:0009188)
 PMID:30595370
GWAS915605_H GCST90092829 Triglyceride levels in HDL 115,082 European ancestry individuals T 0.89964 2E-137 136.699 rs12679834 0.167002 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90060830 Sphingomyelin(42:3)_[M+H]1+ levels 5,662 Pakistani ancestry individuals G NR 3E-26 25.523 rs12679834 0.0835 sphingomyelin measurement (EFO:0010118)
 PMID:34503513
GWAS930805_H GCST90092902 Triglyceride levels in medium HDL 115,082 European ancestry individuals T 0.89964 8E-118 117.097 rs12679834 0.155004 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS943468_H GCST90092907 Cholesteryl esters to total lipids ratio in medium LDL 115,082 European ancestry individuals T 0.89964 9E-108 107.046 rs12679834 0.150391 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:35213538
None Available GCST90301976 Total cholesterol to total lipids ratio in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.8997 1E-30 30 rs12679834 0.075 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
None Available GCST90454454 Metabolic syndrome 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls T 0.08967 4E-29 28.398 rs12679834 0.20248 metabolic syndrome (EFO:0000195)
 PMID:38201907
Database Acc Id Source(s)
GWAS Catalog GCST90269718 GWAS Catalog

RGD Curation Notes
Note Type Note Reference