GWAS731646_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS731646_H (mean corpuscular volume QTL GWAS731646 (human)) Homo sapiens

Symbol: GWAS731646_H
Name: mean corpuscular volume QTL GWAS731646 (human)
RGD ID: 407082670
Trait: mean corpuscular volume
Measurement Type: mean corpuscular volume   (CMO:0000038)    
LOD Score: Not Available
P Value: 5.0E-19
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38316,891,490 - 16,891,491RGD_MAPPER_PIPELINEGRCh38
GRCh37316,932,989 - 16,932,990RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS731646_HHumanmean corpuscular volume  IAGPrs73146904405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS731646_HHumanmean corpuscular volume  IAGPrs73146904405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1314267PLCL2phospholipase C like 231688495517090606Human

Position Markers

Peak: (rs73146904)
Human AssemblyChrPosition (strand)Source
GRCh38316,891,490 - 16,891,491RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
407078440GWAS727416_Hmean corpuscular hemoglobin QTL GWAS727416 (human)4e-17mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)31689149016891491Human
407087848GWAS736824_Herythrocyte count QTL GWAS736824 (human)1e-12erythrocyte countred blood cell count (CMO:0000025)31689149016891491Human
407082670GWAS731646_Hmean corpuscular volume QTL GWAS731646 (human)5e-19mean corpuscular volumemean corpuscular volume (CMO:0000038)31689149016891491Human
407135291GWAS784267_Herythrocyte count QTL GWAS784267 (human)4e-12erythrocyte countred blood cell count (CMO:0000025)31689149016891491Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS727416_H GCST004630 Mean corpuscular hemoglobin 172,332 European ancestry individuals A 0.0736 4E-17 16.398 rs73146904 0.05733242 mean corpuscular hemoglobin (EFO:0004527)
 PMID:27863252
GWAS731646_H GCST004602 Mean corpuscular volume 172,433 European ancestry individuals A 0.0737 5E-19 18.302 rs73146904 0.06045652 mean corpuscular volume (EFO:0004526)
 PMID:27863252
GWAS736824_H GCST004601 Red blood cell count 172,952 European ancestry individuals A 0.0737 1E-12 12 rs73146904 0.04857125 erythrocyte count (EFO:0004305)
 PMID:27863252
GWAS784267_H GCST90002403 Red blood cell count 408,112 British individuals A 0.073152 4E-12 11.398 rs73146904 0.032787975 erythrocyte count (EFO:0004305)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST004602 GWAS Catalog

RGD Curation Notes
Note Type Note Reference